Hostname: page-component-cd9895bd7-gbm5v Total loading time: 0 Render date: 2024-12-23T17:08:17.718Z Has data issue: false hasContentIssue false
  • English
  • Français

The absorption of long-chain fatty acids from the small intestine of the sheep

Published online by Cambridge University Press:  09 March 2007

Aileen M. Lennox  and
G. A. Garton
Aileen M. Lennox
Affiliation:
Rowett Research Institute, Bucksburn, Aberdeen
G. A. Garton
Affiliation:
Rowett Research Institute, Bucksburn, Aberdeen
Rights & Permissions [Opens in a new window]

Abstract

Core share and HTML view are not available for this content. However, as you have access to this content, a full PDF is available via the ‘Save PDF’ action button.

1. Three sheep, each of which was fitted with a rumen cannula and with two pairs of reentrant cannulas in different parts of the small intestine, were used in this study. They were fed on dried grass cubes or hay plus linseed meal and oats: an aqueous solution of polyethylene glycol (PEG) was infused continuously into the rumen.

2. Total lipids were extracted from samples of the chyme entering and leaving the different lengths of the small intestine embraced by the respective cannulas. The lipids were fractionated into unesterified fatty acids, neutral lipids and phospholipids and the contribution of each fraction to the total fatty acids was determined. The samples were also analysed for their PEG content, thus affording an index of the extent to which water had been absorbed from each particular length of intestine.

3. From the above findings and a knowledge of the flow-rate of the digesta, the uptake of unesterified fatty acids and the degree of dissimilation or uptake, or of both, of esterified fatty acids was calculated.

4. The results indicated that, by the time the digesta reached the ileum (i.e. the distal half of the small intestine), the uptake of fatty acids was almost complete, as was also the hydrolytic release of esterified fatty acids.

5. Though there were no gross differences in the overall composition of the unesterified and esterified fatty acids in different parts of the small intestine, it appeared that C18 mono-unsaturated acid, the principal unsaturated unesterified acid, was absorbed somewhat more efficiently than were the major saturated acids (palmitic acid and stearic acid).

Type
Research Article
Information
British Journal of Nutrition , Volume 22 , Issue 2 , May 1968 , pp. 247 - 254
Copyright
Copyright © The Nutrition Society 1968

References

Ash, R. W. (1962). Anim Prod. 4, 309.Google Scholar
Borgström, B., Dahlqvist, A., Lundh, G. & Sjövall, J. (1957). J. clin. Invest. 36, 1521.CrossRefGoogle Scholar
Coombe, J. B. & Kay, R. N. B. (1965). Br. J. Nutr. 19, 325.CrossRefGoogle Scholar
Dole, V. P., James, A. T., Webb, J. P. W., Rizack, M. A. & Sturman, M. F. (1959). J. clin. Invest. 38, 1544.CrossRefGoogle Scholar
Duncan, W. R. H. & Garton, G. A. (1962). J. Lipid Res. 3, 53.CrossRefGoogle Scholar
Duncan, W. R. H. & Garton, G. A. (1963). Biochem. J. 89, 414.CrossRefGoogle Scholar
Duthie, I. F. (1959). Lab. Pract. 8, 408.Google Scholar
Garton, G. A. (1967). Wld Rev. Nutr. Diet. 7, 225.CrossRefGoogle Scholar
Garton, G. A. & Duncan, W. R. H. (1964). Biochem. J. 92, 472.CrossRefGoogle Scholar
Heath, T. J. & Morris, B. (1963). Br. J. Nutr. 17, 465.CrossRefGoogle Scholar
Hofmann, A. F. (1966). Gastroenterology 50, 56.CrossRefGoogle Scholar
Hydén, S. (1955). K. Lantbr Högsk. Annlr 22, 139.Google Scholar
Lennox, A. M., Lough, A. K. & Garton, G. A. (1968). Br. J. Nutr. 22, 237.CrossRefGoogle Scholar
Lough, A. K. & Garton, G. A. (1968). Symp. zool. Soc. Lond. no. 21, p. 163.Google Scholar
Murray, M. G., Reid, R. S. & Sutherland, T. M. (1962). J. Physiol., Lond. 164, 26P.Google Scholar
Oser, B. L. [editor]. (1965). Hawk's Physiological Chemistry, 14th ed., p. 511. New York, Toronto, Sydney and London: McGraw-Hill Book Co.Google Scholar
Scott, D. (1965). Q. Jl exp. Physiol. 50, 312.CrossRefGoogle Scholar
Shorland, F. B., Weenink, R. O., Johns, A. T. & McDonald, I. R. C. (1957). Biochem. J. 67, 328.CrossRefGoogle Scholar
Smith, R. H. (1958). Nature, Lond. 182, 260.CrossRefGoogle Scholar
Taylor, R. B. (1962). Res. vet. Sci. 3, 63.CrossRefGoogle Scholar
Ward, P. F. V., Scott, T. W. & Dawson, R. M. C. (1964). Biochem. J. 92, 60.CrossRefGoogle Scholar