Hostname: page-component-cd9895bd7-dk4vv Total loading time: 0 Render date: 2024-12-25T02:26:49.993Z Has data issue: false hasContentIssue false
  • English
  • Français

Absorption and metabolism of glucose by the mesenteric-drained viscera of sheep fed on dried-grass or ground, maize-based diets

Published online by Cambridge University Press:  09 March 2007

A. N. Janes ,
T. E. C. Weekes  and
D. G. Armstrong
A. N. Janes
Affiliation:
Department of Agricultural Biochemistry and Nutrition, University of Newcastle upon Tyne, Newcastle upon Tyne, NEI 7RU
T. E. C. Weekes
Affiliation:
Department of Agricultural Biochemistry and Nutrition, University of Newcastle upon Tyne, Newcastle upon Tyne, NEI 7RU
D. G. Armstrong
Affiliation:
Department of Agricultural Biochemistry and Nutrition, University of Newcastle upon Tyne, Newcastle upon Tyne, NEI 7RU
Rights & Permissions [Opens in a new window]

Abstract

Core share and HTML view are not available for this content. However, as you have access to this content, a full PDF is available via the ‘Save PDF’ action button.

1. Sheep fitted with re-entrant canulas in the proximal duodenum and terminal ileum were used to determine the amount of α-glucoside entering, and apparently disappearing from, the small intestine when either dried-grass or ground maize-based diets were fed. The fate of any α-glucoside entering the small intestine was studied by comparing the net disappearance of such a-glucoside from the small intestine with the absorption of glucose into the mesenteric venous blood.

2. Glucose absorption from the small intestine was measured in sheep equipped with catheters in the mesenteric vein and carotid artery. A continuous infusion of [6-3H]glucose was used to determine glucose utilization by the mesenteric-drained viscera and the whole-body glucose turnover rate (GTR).

3. The amounts of α-glucoside entering the small intestine when the dried-grass and maize-based diets were given were 13.9 (SE 1.5) and 95.4 (SE 16.2) g/24 h respectively; apparent digestibilities of such α-glucoside in the small intestine were 60 and 90% respectively.

4. The net absorption of glucose into the mesenteric venous blood was —2.03 (SE 1.20) and 19.28 (SE 0.75) mmol/h for the dried-grass and maize-based diets respectively. Similarly, total glucose absorption amounted to 1.52 (SE 1.35) and 23.33 (SE 1.86) mmol/h (equivalent to 7 and 101 g/24 h respectively). These values represented 83 and 11 1% of the a-glucoside apparently disappearing from the small intestine, determined using the re-entrant cannulated sheep.

5. Total glucose absorption represented 8 and 61% of the whole-body GTR for the dried-grass and maize-based diets respectively. Endogenous glucose production was significantly lower when the sheep were fed on the maize-based diet compared with the dried-grass diet.

6. The mesenteric-drained viscera metabolized a small amount of glucose, equivalent to 234 and 17% of the total glucose absorbed for the dried-grass and maize-based diets respectively.

7. It is concluded that a large proportion of the starch entering the small intestine of sheep given a maize-based diet is digested and absorbed as glucose, and thus contributes to the whole-body GTR.

Type
Papers on General Nutrition
Information
British Journal of Nutrition , Volume 54 , Issue 2 , September 1985 , pp. 449 - 458
Copyright
Copyright © The Nutrition Society 1985

References

REFERENCES

Armstrong, D. G. & Smithard, R. R. (1979). Proceedings of the Nutrition Society 38, 283–294.CrossRefGoogle Scholar
Beever, D. E., Coelho Da Silva, J. F. & Armstrong, D. G. (1970). Proceedings of the Nutrition Society 29, 43A.Google Scholar
Bergman, E. N., Katz, M. L. & Kaufman, C. F. (1970). American Journal of Physiology 219, 785–793.CrossRefGoogle Scholar
Clary, J. J., Mitchell, G. E. & Little, C. O. (1967). Journal of Animal Science 26, 917.Google Scholar
Eilers, R. J. (1967). American Journal of Clinical Pathology 41, 212–214.CrossRefGoogle Scholar
Fries, G. F. & Conner, G. H. (1960). Journal of Dairy Science 43, 1851–1852.CrossRefGoogle Scholar
Gawehn, K. & Bergmeyer, H. U. (1974). In Methods in Enzymatic Analysis, pp. 1492–1495 [Bergmeyer, H. U., editor]. New York: Academic Press.Google Scholar
Hogue, D. E., Elliot, J. M., Walker, E. F. & Vidal, H. (1968). Proceedings of the Cornell Nutrition Conference 34, 57–60.Google Scholar
Huntington, G. B. (1982). Journal of Dairy Science 65, 1155–1162.CrossRefGoogle Scholar
Huntington, G. B. (1983). Journal of Nutrition 113, 1157–1164.CrossRefGoogle Scholar
Huntington, G. B. & Prior, R. L. (1983). Journal of Nutrition 113, 2280–2288.CrossRefGoogle Scholar
Huntington, G. B., Prior, R. L. & Britton, R. A. (1980). Journal of Nutrition 110, 1904–1913.CrossRefGoogle Scholar
Huntington, G. B., Prior, R. L. & Britton, R. A. (1981). Journal of Nutrition 111, 1164–1172.CrossRefGoogle Scholar
Janes, A. N., Parker, D. S., Weekes, T. E. C. & Armstrong, D. G. (1984). Journal of Agricultural Science, Cambridge 103, 549–553.CrossRefGoogle Scholar
Janes, A. N., Weekes, T. E. C. & Armstrong, D. G. (1985). Journal of Agricultural Science, Cambridge 104, 435–443.CrossRefGoogle Scholar
Karr, M. R., Little, C.O & Mitchell, G. E. (1966). Journal of Animal Science 25, 652–654.CrossRefGoogle Scholar
Katz, J., Okajima, F., Chenoweth, M. & Dunn, A. (1981). Biochemical Journal 194, 513–524.CrossRefGoogle Scholar
Katz, M. L. & Bergman, E. N. (1969). American Journal of Physiology 216, 946–952.CrossRefGoogle Scholar
MacRae, J. C. & Armstrong, D. G. (1966). Proceedings of the Nutrition Society 25, xxxiii.Google Scholar
MacRae, J. C. & Armstrong, D. G. (1969). British Journal of Nutrition 23, 15–23.CrossRefGoogle Scholar
Mayes, R. W. & Ørskov, E. R. (1974). British Journal of Nutrition 32, 143–153.CrossRefGoogle Scholar
Ørskov, E. R., Fraser, C. & Kay, R. N. B. (1969). British Journal of Nutrition 23, 217–226.CrossRefGoogle Scholar
Russell, J. R., Young, A. W. & Jorgensen, N. A. (1981). Journal of Animal Science 52, 1177–1182.CrossRefGoogle Scholar
Symonds, H. W. & Baird, G. D. (1975). British Veterinary Journal 131, 17–22.CrossRefGoogle Scholar
Thivend, P. (1974). Proceedings of the Nutrition Society 33, 7A.Google Scholar
Tucker, R. E., Little, C. O., Mitchell, G. E., Hayes, B. W. & Karr, M. R. (1966). Journal of Animal Science 25, 911.Google Scholar
Tucker, R. E., Mitchell, G. E. & Little, C. O. (1968). Journal of Animal Science 27, 824–826.CrossRefGoogle Scholar
Van der Walt, J. G., Baird, G. D. & Bergman, E. N. (1983). British Journal of Nutrition 50, 267–280.CrossRefGoogle Scholar
Williams, C. H., David, D. J. & Ismaa, O. I. (1962). Journal of Agricultural Science, Cambridge 59, 381–385.CrossRefGoogle Scholar