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A Randomized Controlled Trial of the Effectiveness of Computer-Assisted Cognitive Remediation (CACR) in Adolescents with Psychosis or at High Risk of Psychosis

Published online by Cambridge University Press:  01 May 2013

Laurent Holzer ,
Sebastien Urben ,
Christina Moses Passini ,
Laure Jaugey ,
Michael H. Herzog ,
Olivier Halfon  and
Sandrine Pihet
Laurent Holzer*
Affiliation:
Service Universitaire de Psychiatrie de l'Enfant et de l'Adolescent, Lausanne, Switzerland
Sebastien Urben
Affiliation:
Service Universitaire de Psychiatrie de l'Enfant et de l'Adolescent, Lausanne, Switzerland
Christina Moses Passini
Affiliation:
Service Universitaire de Psychiatrie de l'Enfant et de l'Adolescent, Lausanne, Switzerland
Laure Jaugey
Affiliation:
Service Universitaire de Psychiatrie de l'Enfant et de l'Adolescent, Lausanne, Switzerland
Michael H. Herzog
Affiliation:
Ecole Polytechnique Fédérale de Lausanne (EPFL), Switzerland
Olivier Halfon
Affiliation:
Service Universitaire de Psychiatrie de l'Enfant et de l'Adolescent, Lausanne, Switzerland
Sandrine Pihet
Affiliation:
Service Universitaire de Psychiatrie de l'Enfant et de l'Adolescent, Lausanne, Switzerland
*
Reprint requests to Laurent Holzer, Centre Thérapeutique de Jour pour Adolescents, Avenue de Beaumont 48, 1012 Lausanne, Switzerland. E-mail: [email protected]
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Abstract

Background: Computer assisted cognitive remediation (CACR) was demonstrated to be efficient in improving cognitive deficits in adults with psychosis. However, scarce studies explored the outcome of CACR in adolescents with psychosis or at high risk. Aims: To investigate the effectiveness of a computer-assisted cognitive remediation (CACR) program in adolescents with psychosis or at high risk. Method: Intention to treat analyses included 32 adolescents who participated in a blinded 8-week randomized controlled trial of CACR treatment compared to computer games (CG). Cognitive abilities, symptoms and psychosocial functioning were assessed at baseline and posttreatment. Results: Improvement in visuospatial abilities was significantly greater in the CACR group than in CG. Other cognitive functions, psychotic symptoms and psychosocial functioning improved significantly, but at similar rates, in the two groups. Conclusion: CACR can be successfully administered in this population; it proved to be effective over and above CG for the most intensively trained cognitive ability.

Keywords

Psychosisadolescentcognitive remediationcomputercontrolled trial
Type
Research Article
Information
Behavioural and Cognitive Psychotherapy , Volume 42 , Issue 4 , July 2014 , pp. 421 - 434
Copyright
Copyright © British Association for Behavioural and Cognitive Psychotherapies 2013 

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