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Pathway rewiring with neural transplantation

Published online by Cambridge University Press:  04 February 2010

Piergiorgio Strata  and
Ferdinando Rossi
Piergiorgio Strata
Affiliation:
Department of Anatomy and Human Physiology, University of Turin, 10125 Turin, Italy. [email protected]
Ferdinando Rossi
Affiliation:
Department of Anatomy and Human Physiology, University of Turin, 10125 Turin, Italy. [email protected]
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Abstract

A lesion to the brain is not necessary for a successful neural transplantation. Embryonic Purkinje cells placed on the surface of an uninjured adult cerebellum can develop and migrate into the host molecular layer. Both the Purkinje cells that migrated into the host cerebellum and those that remained in the graft were innervated by collateral sprouting of adult intact climbing fibers.

Type
Open Peer Commentary
Information
Behavioral and Brain Sciences , Volume 18 , Issue 1: An International Journal of Current Research and Theory with Open Peer Commentary , March 1995 , pp. 73
Copyright
Copyright © Cambridge University Press 1995

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