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A novel protein family of neuronal modulators

Published online by Cambridge University Press:  04 February 2010

Ken Takamatsu
Ken Takamatsu*
Affiliation:
Department of Physiology, Toho University School of Medicine, 5-21-16, Ohmori-nishi, Ohta-ku, Tokyo 143, Japan. physiken@med. toho-u.ac.jp
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Abstract

A number of proteins homologous to recoverin have been identified in the brains of the several vertebrate species. The brainderived members originally contain four EF-hand domains, but NH2- terminal domain is aberrant. Many of these proteins inhibited light-induced rhodopsin phosphorylation at high [Ca2+], suggesting that the brain-derived members may act as a Ca2+-sensitive modulator of receptor phosphorylation, as recoverin does.

Type
Article Commentary
Information
Behavioral and Brain Sciences , Volume 18 , Special Issue 3: An International Journal of Current Research and Theory with Open Peer Commentary , September 1995 , pp. 489 - 490
Copyright
Copyright © Cambridge University Press 1995

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