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Multiple potential mechanisms of graft action is not a new idea

Published online by Cambridge University Press:  04 February 2010

Stephen B. Dunnett
Affiliation:
MRC Cambridge Centre for Brain Repair and Department of Experimental Psychology, University of Cambridge, Cambridge, CB2 3EB, United Kingdom. [email protected]

Abstract

It is well established that neural grafts can exert functional effects on the host animal by a multiplicity of different mechanisms – by diffuse release of trophic molecules, neurohormones, and deficient neurotransmitters, as well as by growth and reformation of neural circuits. Our challenge is to understand how these different mechanisms complement each other.

Type
Open Peer Commentary
Copyright
Copyright © Cambridge University Press 1995

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