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The gap between episodic memory and experiment: Can c-fos expression replace recognition testing?

Published online by Cambridge University Press:  01 June 1999

Jan Bures  and
Andre A. Fenton
Jan Bures
Affiliation:
Institute of Physiology, Academy of Sciences, 14220 Prague, Czech [email protected]
Andre A. Fenton
Affiliation:
Institute of Physiology, Academy of Sciences, 14220 Prague, Czech [email protected]
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Abstract

The effort to identify the neural substrate of episodic recall, though ambitious, lacks experimental support. By considering the data on c-fos activation by novel and familiar stimuli in recognition studies, we illustrate how inadequate experimental designs permit alternative interpretations. We stress that interpretation of c-fos expression changes should be supported by adequate recognition tests.

Type
Open Peer Commentary
Information
Behavioral and Brain Sciences , Volume 22 , Issue 3 , June 1999 , pp. 445 - 446
Copyright
© 1999 Cambridge University Press

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