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Sexual differentiation of callosal size: Hormonal mechanisms and the choice of an animal model

Published online by Cambridge University Press:  01 June 1998

M. J. Baum  and
S. A. Tobet
M. J. Baum
Affiliation:
Department of Biology, Boston University, Boston, MA 02215 [email protected] Program in Neuroscience, Harvard Medical School, Boston, MA 02115
S. A. Tobet
Affiliation:
Department of Biomedical Sciences, The Shriver Center, Waltham, MA 02254 [email protected] Program in Neuroscience, Harvard Medical School, Boston, MA 02115
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Abstract

Studies of callosal sexual differentiation have concentrated on global measures of callosal size, using the rat as a model for studies of potential hormonal mechanisms. It is time to shift the study of callosal sexual differentiation to a more cellular level. Finally, there are potential problems with using the female rat as the primary model for understanding hormonal mechanisms during postnatal life.

Type
Open Peer Commentary
Information
Behavioral and Brain Sciences , Volume 21 , Issue 3 , June 1998 , pp. 328
Copyright
© 1998 Cambridge University Press

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