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More inhibition and less excitation needed in the fight against pain

Published online by Cambridge University Press:  01 September 1997

Rob W. Clarke
Rob W. Clarke
Affiliation:
Department of Physiology and Environmental Science, University of Nottingham, Loughborough LE12 5RD, United [email protected]
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Abstract

Recent pain research has concentrated heavily on excitatory processes. However, noxious stimuli activate excitatory and inhibitory systems. As failure of inhibition could underlie some forms of pathological pain, it may be argued that a full understanding of the mechanisms underlying the development of pain states can only come from a consideration of all the central sequelae of injurious stimuli. [berkley; blumberg et al.; coderre & katz; dickenson; mcmahon; weisenfeld-hallin et al.]

Type
Open Peer Commentary
Information
Behavioral and Brain Sciences , Volume 20 , Issue 3 , September 1997 , pp. 443 - 444
Copyright
© 1997 Cambridge University Press

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