Hostname: page-component-cd9895bd7-mkpzs Total loading time: 0 Render date: 2024-12-27T09:44:30.582Z Has data issue: false hasContentIssue false
  • English
  • Français

Short- and long-term effects of postpartum oral bolus v. subcutaneous Ca supplements on blood metabolites and productivity of Holstein cows fed a prepartum anionic diet

Published online by Cambridge University Press:  28 October 2019

M. Jahani-Moghadam ,
A. Teimouri Yansari ,
Y. Chashnidel ,
E. Dirandeh  and
E. Mahjoubi Open the ORCID record for E. Mahjoubi [Opens in a new window]
M. Jahani-Moghadam
Affiliation:
Department of Animal Science, Sari Agriculture and Natural Resource Science University, Sari 48181-68984, Iran
A. Teimouri Yansari
Affiliation:
Department of Animal Science, Sari Agriculture and Natural Resource Science University, Sari 48181-68984, Iran
Y. Chashnidel
Affiliation:
Department of Animal Science, Sari Agriculture and Natural Resource Science University, Sari 48181-68984, Iran
E. Dirandeh
Affiliation:
Department of Animal Science, Sari Agriculture and Natural Resource Science University, Sari 48181-68984, Iran
E. Mahjoubi*
Affiliation:
Department of Animal Science, University of Zanjan, Zanjan 45371-38791, Iran
*
†E-mail: [email protected]; [email protected]
Get access

Abstract

Little information is available regarding the calcium (Ca) dynamics and how its concentration is influenced following the Ca treatment (injection or bolus) after calving in dairy cows. To evaluate the short- and long-term effects of different sources of Ca supplement to animals fed anionic diets during the pre-partum period, 36 multiparous Holstein cows were randomly assigned to 1 of 3 treatments: (1) control group without Ca supplement (CON); (2) subcutaneous injection of 500 ml of 40% w/v Ca borogluconate immediately post-calving (SUB) and (3) oral supplement of Ca bolus containing 45 g Ca immediately and 24 h post-calving (BOL). Serum concentrations of Ca, P and Mg were measured. Serum concentration of Ca was affected by treatments at 48 h of post-calving (P < 0.01). The mean Ca at 6 h was greater in SUB compared to CON group (2.34 v. 2.01 mmol/l; P < 0.002). The lowest Ca concentration at 12 h was related to CON cows compared with BOL and SUB cows (1.90, 2.16 and 2.14 mmol/l, respectively; P < 0.02); a similar trend was observed 24 h post-calving (P < 0.02). Serum concentrations of P and Mg were not influenced by treatments. Yield of milk, milk protein and fat-corrected milk were lowest (P < 0.05) in SUB cows within 3 weeks of lactation in comparison with CON and BOL cows. However, milk yield and milk composition did not show any difference among treatments throughout the first 3 months post-calving. In general, under conditions of this experiment, Ca supplements to fresh cows as an oral bolus are recommended in comparison with subcutaneous injection.

Keywords

calcium dynamicmilk fevermilk yieldsubclinical hypocalcaemiatransition period
Type
Research Article
Information
animal , Volume 14 , Issue 5 , May 2020 , pp. 983 - 990
Copyright
© The Animal Consortium 2019

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Amanlou, H, Akbari, A, Farsuni, NE and Silva-Del-Río, N 2016. Effects of subcutaneous calcium administration at calving on mineral status, health, and production of Holstein cows. Journal of Dairy Science 99, 9199–9210.CrossRefGoogle ScholarPubMed
Association of Official Analytical Chemists (AOAC) 2000. Official methods of analysis, volume 1, 17th edition. AOAC, Arlington, VA, USA.Google Scholar
Daniel, RCW 1983. Motility of the rumen and abomasum during hypocalcemia. Canadian Journal of Comparative Medicine 47, 276–280.Google Scholar
Dhiman, T and Sasidharan, V 1999. Effectiveness of calcium chloride in increasing blood calcium concentrations of periparturient dairy cows. Journal of Animal Science 77, 1597–1605.CrossRefGoogle ScholarPubMed
Domino, AR, Korzec, HC and McArt, JAA 2017. Field trial of 2 calcium supplements on early lactation health and production in multiparous Holstein cows. Journal of Dairy Science 100, 9681–9690.CrossRefGoogle ScholarPubMed
Goff, JP 1999. Treatment of calcium, phosphorus, and magnesium balance disorders. Veterinary Clinics of North America: Food Animal Practice 15, 619–639.Google ScholarPubMed
Goff, JP 2000. Pathophysiology of calcium and phosphorus disorders. Veterinary Clinics of North America: Food Animal Practice 16, 319–337.Google ScholarPubMed
Goff, JP, Horst, RL and Jardon, PW 1996. Field trials of an oral calcium propionate paste as an aid to prevent milk fever in periparturient dairy cows. Journal of Dairy Science 79, 378–383.CrossRefGoogle ScholarPubMed
Goff, JP, Liesegang, A and Horst, RL 2014. Diet-induced pseudohypoparathyroidism: a hypocalcemia and milk fever risk factor. Journal of Dairy Science 97, 1520–1528.CrossRefGoogle ScholarPubMed
Hesters, NL, Yates, DJ and Hunt, H 1996. Disorders of calcium metabolism. In Large animal internal medicine (ed. Smith, BP), pp. 1464–1471. Mosby, St. Louis, MO, USA.Google Scholar
Iranian Council of Animal Care 1995. Guide to the care and use of experimental animals, volume 1, Isfahan University of Technology, Isfahan, Iran.Google Scholar
Jackson, P and Cockcroft, PD 2002. Clinical examination of farm animals. Blackwell Science Ltd, Oxford, UK.CrossRefGoogle Scholar
Jahani-Moghadam, M, Chashnidel, Y, Teimouri-Yansari, A, Mahjoubi, E and Dirandeh, E 2018. Effect of oral calcium bolus administration on milk production, concentrations of minerals and metabolites in serum, early-lactation health status, and reproductive performance of Holstein dairy cows. New Zealand Veterinary Journal 66, 132–137.CrossRefGoogle ScholarPubMed
Khorasani, GR, Janzen, RA, McGill, WB and Kennelly, JJ 1997. Site and extent of mineral absorption in lactating cows fed whole-crop cereal grain silage of alfalfa silage. Journal of Animal Science 75, 239–248.CrossRefGoogle ScholarPubMed
Leno, BM, Ryan, C, Stokol, T, Kirk, D, Zanzalari, Z, Chapman, J and Overton, T 2017. Effects of prepartum dietary cation-anion difference on aspects of peripartum mineral and energy metabolism and performance of multiparous Holstein cows. Journal of Dairy Science 100, 4604–4622.CrossRefGoogle ScholarPubMed
Martinez, N, Risco, CA, Lima, FS, Bisinotto, RS, Greco, LF, Ribeiro, ES, Maunsell, F, Galvão, K and Santos, JEP 2012. Evaluation of peripartal calcium status, energetic profile, and neutrophil function in dairy cows at low or high risk of developing uterine disease. Journal of Dairy Science 95, 7158–7172.CrossRefGoogle ScholarPubMed
Martinez, N, Sinedino, LDP, Bisinotto, RS, Daetz, R, Lopera, C, Risco, CA, Galvão, KN, Thatcher, WW and Santos, JEP 2016a. Effects of oral calcium supplementation on mineral and acid-base status, energy metabolites and health of postpartum dairy cows. Journal of Dairy Science 99, 8397–8416.CrossRefGoogle ScholarPubMed
Martinez, N, Sinedino, LDP, Bisinotto, RS, Daetz, R, Risco, CA, Galvão, KN, Thatcher, WW and Santos, JEP 2016b. Effects of oral calcium supplementation on productive and reproductive performance in Holstein cows. Journal of Dairy Science 99, 8417–8430.CrossRefGoogle ScholarPubMed
Martinez, N, Sinedino, LDP, Bisinotto, RS, Ribeiro, ES, Gomes, GC, Lima, FS, Greco, LF, Risco, CA, Galvão, KN, Taylor-Rodriguez, D, Driver, JP, Thatcher, WW and Santos, JEP 2014. Effect of induced subclinical hypocalcemia on physiological responses and neutrophil function in dairy cows. Journal of Dairy Science 97, 874–887.CrossRefGoogle ScholarPubMed
Melendez, P, Donovan, GA, Risco, CA, Hall, MB, Littell, R and Goff, JP 2002. Metabolic responses of transition Holstein cows fed anionic salts and supplemented at calving with calcium and energy. Journal of Dairy Science 85, 1085–1092.CrossRefGoogle Scholar
Mohebbi-Fani, M and Azadnia, P 2012. The effect of subcutaneous injection of calcium borogluconate on serum levels of calcium, phosphorus and magnesium in newly calved cows. Comparative Clinical Pathology 21, 1647–1652.CrossRefGoogle Scholar
Moore, SJ, VanDeHaar, MJ, Sharma, BK, Bilbeam, TE, Beede, DK, Buchholtz, HF, Liesman, JS, Horst, RL and Goff, JP 2000. Effects of altering dietary cation-anion difference on calcium and energy metabolism in peripartum cows. Journal of Dairy Science 83, 2095–2104.CrossRefGoogle ScholarPubMed
National Research Council (NRC ) 2001. Nutrient requirements of dairy cattle, 7th revised edition. National Academy Press, Washington, DC, USA.Google Scholar
Neves, RC, Leno, BM, Bach, KD and McArt, JAA 2018. Epidemiology of subclinical hypocalcemia in early-lactation Holstein dairy cows: the temporal associations of plasma calcium concentration in the first 4 days in milk with disease and milk production. Journal of Dairy Science 101, 9321–9331.CrossRefGoogle ScholarPubMed
Oetzel, GR 1996. Effect of calcium chloride gel treatment in dairy cows on incidence of periparturient diseases. Journal of the American Veterinary Medical Association 209, 958–961.Google ScholarPubMed
Oetzel, GR and Miller, BE 2012. Effect of oral calcium bolus supplementation on early-lactation health and milk yield in commercial dairy herds. Journal of Dairy Science 95, 7051–7065.CrossRefGoogle ScholarPubMed
Ramos-Nieves, JM, Thering, BJ, Waldron, MR, Jardon, PW and Overton, TR 2009. Effects of anion supplementation to low-potassium prepartum diets on macromineral status and performance of periparturient dairy cows. Journal of Dairy Science 92, 5677–5691.CrossRefGoogle ScholarPubMed
Reinhardt, TA, Lippolis, JD, McCluskey, BJ, Goff, JP and Horst, RL 2011. Prevalence of subclinical hypocalcemia in dairy herds. Veterinary Journal 188, 122–124.CrossRefGoogle ScholarPubMed
Schröder, B, Wilkens, MR, Ricken, GE, Leonhard-Marek, S, Fraser, DR and Breves, G 2015. Calcium transport in bovine rumen epithelium as affected by luminal Ca concentrations and Ca sources. Physiological Reports 11, e12615.CrossRefGoogle Scholar
Van Soest, PJ, Robertson, JB and Lewis, BA 1991. Methods for dietary fiber, neutral detergent fiber, and nonstarch polysaccharides in relation to animal nutrition. Journal of Dairy Science 74, 3583–3597.CrossRefGoogle ScholarPubMed
Wildman, EE, Jones, GM, Wagner, PE, Boman, RL, Trout, HF and Lesch, TN 1982. A dairy cow body condition scoring system and its relationship to selected production variables in high producing Holstein dairy cattle. Journal of Dairy Science 65, 495–501.CrossRefGoogle Scholar
Supplementary material: File

Jahani-Moghadam et al. supplementary material

Jahani-Moghadam et al. supplementary material

Download Jahani-Moghadam et al. supplementary material(File)
File 38.7 KB