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IgG absorption by Santa Ines lambs fed Holstein bovine colostrum or Santa Ines ovine colostrum

Published online by Cambridge University Press:  11 February 2010

D. B. Moretti ,
L. Kindlein ,
P. Pauletti  and
R. Machado-Neto
D. B. Moretti
Affiliation:
Departament of Animal Science, University of São Paulo, USP/ESALQ, Avenue Pádua Dias, 11, Piracicaba, São Paulo, Brazil
L. Kindlein
Affiliation:
Departament of Preventive Medicine Veterinary, Veterinary Faculty, Rio Grande do Sul Federal University, UFRGS, Avenue Bento Gonçalvez 8834, Porto Alegre, Rio Grande do Sul, Brazil
P. Pauletti
Affiliation:
Departament of Animal Science, University of São Paulo, USP/ESALQ, Avenue Pádua Dias, 11, Piracicaba, São Paulo, Brazil
R. Machado-Neto*
Affiliation:
Departament of Animal Science, University of São Paulo, USP/ESALQ, Avenue Pádua Dias, 11, Piracicaba, São Paulo, Brazil
*
†E-mail: [email protected]
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Abstract

The objective of this study was to evaluate the immunoglobulin G (IgG) absorption by Santa Ines lambs under two colostrum management systems usually used by producers. Twenty-seven Santa Ines newborn lambs received two meals of 250 ml of bovine colostrum from Holstein cows (BC group) or ovine colostrum from Santa Ines ewes (OC group) at 0 and 6 h of life. Pools of BC and OC were analyzed by radial immunodiffusion to quantify IgG. Results are expressed as least-square means and standard errors of mean (means ± s.e.m.). The concentration of IgG in bovine and ovine pools averaged 115.7 ± 20.5 and 48.1 ± 5.0 mg/ml, respectively, levels of concentration found in similar regular colostrum managements. The efficiency of IgG absorption was evaluated under two aspects, maximum apparent efficiency of absorption and total apparent efficiency of absorption (AEAmax and AEAtotal, respectively). The AEAmax was calculated taking into account the mass of IgG ingested just in the first meal of colostrum at birth and the serum IgG concentration at 6 h while the AEAtotal took into account the serum IgG concentration at 24 h of life that reflects the first colostrum offered at birth and the second meal at 6 h. The IgG and apparent efficiency of absorption results were transformed into the square root and log base 10, respectively, and were presented as geometric least-square means. In BC, lower (P < 0.05) AEAmax and AEAtotal were verified (14.2% and 15.6%, respectively), in relation to OC (23.6% and 24.4%, respectively). Serum IgG concentrations at 24 h were significantly higher (P < 0.05) in BC (31.4 mg/ml, respectively) compared with OC (22.2 mg/ml, respectively). The results in this study confirm that there is a limitation to the process of IgG absorption by the enterocytes of newborn lambs, which determined a nonlinear behavior of passive immunity acquisition. Similar values of AEAmax and AEAtotal for the two sources of colostrum reveal that the process of IgG absorption from the first and second meals during the first 6 h of life did not change and indicates that the ingestion of a second feeding of quality colostrum can enhance the acquisition of immune protection of newborn lambs.

Keywords

colostrum managementpassive immunityovineantibody absorption
Type
Full Paper
Information
animal , Volume 4 , Issue 6 , June 2010 , pp. 933 - 937
Copyright
Copyright © The Animal Consortium 2010

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References

Ahmad, R, Khan, A, Javed, MT, Hussain, I 2000. The level of immunoglobulins in relation to neonatal lamb mortality in Pak-Karakul sheep. Veterinarski Arhiv 70, 129–139.Google Scholar
Álvarez, V, Arranz, J, Daltabiut-Test, J, Leginagoikoa, I, Juste, RA, Amorena, B, Andrés, D, Lujén, LL, Badiola, JJ, Berriatua, E 2005. Relative contribuition of colostrum from Maedi-Visna virus (MVV) infected ewes to MVV-seroprevalence in lambs. Research in Veterinary Science 78, 237–243.CrossRefGoogle Scholar
Besser, TE, Garmedia, AE, McGuire, TC, Gay, CC 1985. Effect of colostral immunoglobulin G1 and immunoglobulin M concentration on immunoglobulin absorption in calves. Journal of Dairy Science 68, 2033–2037.CrossRefGoogle ScholarPubMed
Besser, TE, Osborn, D 1993. Effect of bovine serum albumin on passive transfer of immunoglobulin G1 to newborn calves. Veterinary Immunology and Immunopathology 37, 321–327.CrossRefGoogle ScholarPubMed
Boland, TM, Brophy, PO, Callan, JJ, Quinn, PJ, Nowakowski, P, Crosby, TF 2004. The effect of mineral-block components when offered to ewes in late pregnancy on colostrum yield and immunoglobulin G absorption in their lambs. Animal Science 79, 293–302.CrossRefGoogle Scholar
Boland, TM, Guinan, M, Brophy, PO, Callan, JJ, Quinn, PJ, Nowakowski, P, Crosby, TF 2005. The effect of varying levels of mineral and iodine supplementation to ewes during late pregnancy on serum immunoglobulin G concentrations in their progeny. Animal Science 80, 209–218.CrossRefGoogle Scholar
Boland, TM, Hayes, L, Sweeney, T, Callan, JJ, Baird, AW, Keely, S, Crosby, TF 2008. The effects of cobalt and iodine supplementation of the pregnant ewe diet on immunoglobulin G, vitamin E, T3 and T4 levels in the progeny. Animal 2, 197–206.CrossRefGoogle ScholarPubMed
Brambell, JWR 1958. The passive immunity of the young mammal. Biological Reviews 33, 488–531.CrossRefGoogle Scholar
Callado, AKC, Castro, RS, Teixeira, MFS 2001. Lentivírus de pequenos ruminantes (CAEV e Maedi-visna): revisão e perspectivas. Pesquisa Veterinária Brasileira 21, 87–97.CrossRefGoogle Scholar
Campbell, SG, Siegel, MJ, Knowlton, BJ 1977. Sheep immunoglobulins and their transmission to the neonatal lamb. New Zealand Veterinary Journal 25, 361–365.CrossRefGoogle Scholar
Castro, N, Capote, J, Álvarez, S, Argüello, A 2005. Effects of liophilized colostrum and different colostrum feeding regiments on passive transfer of immunoglobulin G in Majorera Goat Kids. Journal of Dairy Science 88, 3650–3654.CrossRefGoogle Scholar
Christley, RM, Morgan, KL, Parkin, TDH, Franch, NP 2003. Factors related to the risk of neonatal mortality, birth-weight and serum immunoglobulin concentration in lambs in the UK. Preventive Veterinary Medicine 57, 209–226.CrossRefGoogle Scholar
Fleenor, WA, Stott, GH 1980. Hydrometer test for estimation of immunoglobulin concentration in bovine colostrum. Journal of Dairy Science 63, 973–977.CrossRefGoogle ScholarPubMed
Foley, JA, Otterby, DE 1978. Availability, storage, treatment, composition and feeding value of surplus colostrum: a review. Journal of Dairy Science 61, 1033–1060.CrossRefGoogle Scholar
Hodgson, JC, Moon, GM, Hay, LA, Quirie, M 1992. Effectiveness of substitute colostrum in preventing disease in newborn lambs. British Society of Animal Production 15, 163–165.Google Scholar
Hopkins, BA, Quigley, JD 1997. Effects of method of colostrum feeding and colostrum supplementation on concentrations of immunoglobulin G in the serum of neonates’ calves. Journal of Dairy Science 80, 979–983.CrossRefGoogle ScholarPubMed
Husband, AJ, Brandon, MR, Lascelles, AK 1973. Comparison of freezing and lyophilizing for preservation of colostrum. Australian Journal of Experimental Biology and Medical Science 51, 707–710.CrossRefGoogle Scholar
Kindlein, L, Pauletti, P, Bagaldo, AR, Machado-Neto, R 2007. Efeito do fornecimento adicional de colostro sobre as concentrações séricas de IgG, PT e IGF-I de bezerros neonatos. Revista Brasileira de Saúde e Produção Animal 8, 375–385.Google Scholar
Logan, EF, Foster, WH, Irwin, D 1978. A note on bovine colostrums as an alternative source of immunoglobulin for lambs. Animal Production 26, 93–96.Google Scholar
Loste, A, Ramos, JJ, Frenández, A, Ferrer, LM, Lacasta, D, Verde, MT, Marca, MC, Ortín, A 2008. Effect of colostrum treated by heat on immunological parameters in newborn lambs. Livestock Science 117, 176–183.CrossRefGoogle Scholar
Machado Neto, R, Cassoli, LD, Bessi, R, Pauletti, P 2004. Avaliação do fornecimento adicional de colostro para bezerros. Revista Brasileira de Zootecnia 33, 420–425.CrossRefGoogle Scholar
Machado Neto, R, Packer, IU, Bonila, LM, Figueiredo LA Razzok, AG, Cândido, JG 1997. Concentração de IgG sérica em bezerros das raças Nelore, Guzerá, Gir e Caracu: 2. Efeitos sobre crescimento e mortalidade até a desmama. Revista Brasileira de Zootecnia 26, 920–923.Google Scholar
Mancini, G, Carbonara, AO, Hermans, JF 1965. Immunochemical quantitation of antigens by single radial immunodiffusion. Immunochemistry 2, 253–254.CrossRefGoogle ScholarPubMed
Nóbrega, JE, Riet-Correa, F, Nóbrega, RS, Medeiros, JM, Vasconcelos, JS, Simões, SVD, Tabosa, IM 2005. Mortalidade perinatal de cordeiros no semi-árido da Paraíba. Pesquisa Veterinária Brasileira 25, 171–178.CrossRefGoogle Scholar
Nocek, JE, Braund, DG, Warner, RG 1984. Influence of neonatal colostrum administration, immunoglobulin, and continued feeding of colostrum on calf gain, health and serum protein. Journal of Dairy Science 67, 319–333.CrossRefGoogle ScholarPubMed
Nowak, R, Poidron, P 2006. From birth to colostrum: early steps leading to lamb survival. Reproduction, Nutrition, Development 46, 431–436.CrossRefGoogle ScholarPubMed
O’Doherty, JV, Crosby, TF 1997. The effect of diet in late pregnance on colostrum production and immunoglobulin absorption in sheep. Journal of Animal Science 64, 87–96.CrossRefGoogle Scholar
Oyeniyi, OO, Hunter, AG 1978. Colostral constituents including immunoglobulins in the first three milkings postpartum. Journal of Dairy Science 61, 44–48.CrossRefGoogle ScholarPubMed
Pauletti, P, Bagaldo, AR, Kindlein, L, de Paz, CCP, Lanna, DPD, Machado Neto, R 2005. IGF-I e IgG séricos e nas secreções lácteas em vacas tratadas com rbST no período pré-parto. Revista Brasileira de Zootecnia 34, 976–986.CrossRefGoogle Scholar
Quigley, JD, Carson, AF, Polo, J 2002. Immunoglobulin derived from bovine plasma as a replacement for colostrum in newborn lambs. Veterinary Therapeutics 3, 262–269.Google ScholarPubMed
Quigley, JD, Fike, DL, Egerton, MN, Drewry, JJ, Arthington, JD 1998. Effects of a colostrum replacement product derived from serum on immunoglobulin G absorption by calves. Journal of Dairy Science 81, 1936–1939.CrossRefGoogle ScholarPubMed
Quigley, JD, French, P, James, RE 2000. Short communication: Effect of pH on absorption of immunoglobulin G in neonatal calves. Journal of Dairy Science 83, 1853–1855.CrossRefGoogle ScholarPubMed
Quigley, JD, Martin, KR, Dowlen, HH, Wallis, LB, Lamar, K 1994. Immunoglobulin concentration, specific gravity and nitrogen fractions of colostrum from Jersey cows. Journal of Dairy Science 77, 264–269.CrossRefGoogle Scholar
Quigley, JD, Strohbehn, RE, Kost, CJ, O’Brien, MM 2001. Formulation of colostrum supplements, colostrum replacers and acquisition of passive immunity in neonatal calves. Journal of Dairy Science 84, 2059–2065.CrossRefGoogle ScholarPubMed
Rocha, RX, Bondan, C, Marinho, R, Lopes, ATAL, Cecim, M 2007. Dextran iron in anemic lambs: effects on reticulocytosis and free radical production. Ciência Rural 37, 1344–1348.CrossRefGoogle Scholar
Statistical Analysis System 1999. SAS: user’s guide statistics, 6th edition. SAS, Cary, USA, 956 pp.Google Scholar