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Effects of fixed-time artificial insemination using triptorelin on the reproductive performance of pigs: a meta-analysis

Published online by Cambridge University Press:  20 December 2019

Z. Wang ,
B. S. Liu ,
X. Y. Wang ,
J. L. Peng ,
X. Q. Huang ,
H. Tian ,
Q. H. Wei  and
L. Q. Wang
Z. Wang
Affiliation:
College of Animal Science and Technology, Jiangxi Agricultural University, Nanchang 330045, China
B. S. Liu
Affiliation:
College of Animal Science and Technology, Jiangxi Agricultural University, Nanchang 330045, China
X. Y. Wang
Affiliation:
College of Animal Science and Technology, Jiangxi Agricultural University, Nanchang 330045, China
J. L. Peng
Affiliation:
College of Animal Science and Technology, Jiangxi Agricultural University, Nanchang 330045, China
X. Q. Huang
Affiliation:
College of Animal Science and Technology, Jiangxi Agricultural University, Nanchang 330045, China
H. Tian
Affiliation:
College of Animal Science and Technology, Jiangxi Agricultural University, Nanchang 330045, China
Q. H. Wei
Affiliation:
College of Animal Science and Technology, Jiangxi Agricultural University, Nanchang 330045, China
L. Q. Wang*
Affiliation:
College of Animal Science and Technology, Jiangxi Agricultural University, Nanchang 330045, China
*
†E-mail: [email protected]
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Abstract

Triptorelin (TRI), a gonadotropin-releasing hormone agonist allowing ovulation synchronization in pigs, is indispensable for fixed-time artificial insemination (FTAI) protocols. However, the effect of FTAI using TRI (FTAI-TRI) on the reproductive performance is controversial. We performed a meta-analysis to determine whether FTAI-TRI affects reproductive performance of pigs, including pregnancy rate (PR), number of pigs born alive per litter (NBA), farrowing rate (FR) and total number of pigs born per litter (TNB). A total of 37 trials from 15 studies were extracted and analysed in Stata. A weighted mean difference (WMD) with 95% confidence interval (CI) was calculated for NBA and TNB, and risk ratio (RR) with 95% CI was calculated for PR and FR. Pregnancy rate, TNB and NBA data were applied to a fixed-effect protocol, and FR data were applied to a random-effect protocol. We found that for weaned sows, the FTAI-TRI group had comparable reproductive performance to the artificial insemination (AI) following oestrus detection (EDAI) group. Fixed-time AI has many advantages, including the elimination of the need to heat-check twice daily, so that FTAI-TRI is a good substitute for EDAI. Subgroup analysis indicated that the optimal timing of triptorelin treatment was 96 h after weaning, which gave significant positive effects on PR (RR = 1.08, P = 0.000) and non-significant positive effects on TNB (WMD = 0.12, P = 0.452). Triptorelin at a dose of 100 μg showed better effects than 200 μg, with significant positive effects on PR (RR = 1.09, P = 0.005) and FR (RR = 1.06, P = 0.036). So a single dose of 100 μg was recommended. The optimal protocol was insemination at 24 h and again at 48 h after triptorelin administration if they remained in standing oestrus, and this provided a significantly higher NBA (WMD = 0.59, P = 0.013) that increased by 0.59. For gilts, the FTAI-TRI group showed decreased (not significant) PR (RR = 0.96, P = 0.127) and significantly decreased FR (RR = 0.93, P = 0.013), TNB (WMD = −0.85, P = 0.006) and NBA (WMD = −0.98, P = 0.000), which were inferior to those in the EDAI group. In conclusion, the effects of FTAI-TRI on the reproductive performance of pigs were parity-, treatment timing-, insemination timing-, and dosage-dependent. Fixed-time AI using triptorelin could effectively replace the EDAI protocol for sows, but not for gilts.

Keywords

GnRH analoguesynchronization of ovulationfertilityswinesystematic review
Type
Research Article
Information
animal , Volume 14 , Issue 7 , July 2020 , pp. 1481 - 1492
Copyright
© The Animal Consortium 2019

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