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The effects of feeding high or low milk levels in early life on growth performance, fecal microbial count and metabolic and inflammatory status of Holstein female calves

Published online by Cambridge University Press:  01 August 2019

M. Alimirzaei ,
Y. A. Alijoo ,
M. Dehghan-Banadaky  and
M. Eslamizad
M. Alimirzaei
Affiliation:
Department of Animal Science, Faculty of Agriculture, Urmia University, Daneshgah Blv, 165, 5756151818 Urmia, West-Azarbayjan, Iran
Y. A. Alijoo*
Affiliation:
Department of Animal Science, Faculty of Agriculture, Urmia University, Daneshgah Blv, 165, 5756151818 Urmia, West-Azarbayjan, Iran
M. Dehghan-Banadaky
Affiliation:
Department of Animal Science, Campus of Agriculture and Natural Resources, University of Tehran, Daneshkadeh St, 4111, 3158777871 Karaj, Tehran, Iran
M. Eslamizad
Affiliation:
Department of Animal Science, Campus of Agriculture and Natural Resources, University of Tehran, Daneshkadeh St, 4111, 3158777871 Karaj, Tehran, Iran
*
†E-mail: [email protected]
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Abstract

Gut microbial colonization and immune response may be affected by milk feeding method. The objective of this study was to determine the effects of feeding high or low volumes of milk on fecal bacterial count, inflammatory response, blood metabolites and growth performance of Holstein female calves. Colostrum-fed calves (n = 48) were randomly assigned to either high milk (HM; n = 24) or low milk (LM; n = 24) feeding groups. Low milk-fed calves were fed pasteurized whole milk at 10% of BW until weaning. In HM group, milk was offered to calves at 20% of BW for the first 3 weeks of life. Then, milk allowance was decreased gradually to reach 10% of BW on day 26 and remained constant until weaning on day 51. Calves were allowed free access to water and starter throughout the experiment. Body weight was measured weekly, and blood samples were taken on days 14, 28 and 57. Fecal samples were collected on days 7, 14 and 21 of age for the measurement of selected microbial species. By design, HM calves consumed more nutrients from milk during the first 3 weeks and they were heavier than LM calves on days 21, 56 and 98. High milk-fed calves had greater serum glucose and triglyceride levels on day 14 with no significant difference between groups on days 28 and 57. Blood urea nitrogen was higher in LM calves on day 14, but it was lower in HM calves on day 28. Calves in LM group had significantly greater blood tumor necrosis factor-α (TNF-α) than HM calves throughout the experiment. Serum amyloid A (SAA) concentration was higher in LM calves on day 14. However, HM calves showed higher levels of SAA at the time of weaning. Feeding high volumes of milk resulted in lower serum cortisol levels on days 14 and 28 but not at the time of weaning in HM calves compared to LM counterparts. Lactobacillus count was higher in feces sample of HM calves. Conversely, the numbers of Escherichia coli was greater in the feces of LM calves. Calves in HM group showed fewer days with fever and tended to have fewer days treated compared to LM group. In conclusion, feeding higher amounts of milk during the first 3 weeks of life improved gut microbiota, inflammation and health status and growth performance of Holstein dairy calves.

Keywords

dairy calfinflammationmilk feedinggut microbiotablood metabolites
Type
Research Article
Information
animal , Volume 14 , Issue 2 , February 2020 , pp. 303 - 311
Copyright
© The Animal Consortium 2019 

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References

Abe, F, Ishibashi, N and Shimamura, S 1995. Effect of administration of bifidobacteria and lactic acid bacteria to newborn calves and piglets. Journal of Dairy Science 78, 2838–2846.CrossRefGoogle ScholarPubMed
Association of Official Analytical Chemists (AOAC) 1990. Official methods of analysis, 15thedition. AOAC, Arlington, VA, USA.Google Scholar
Bach, A, Aris, A, Vidal, M, Fabregas, F and Terre, M 2017. Influence of milk processing temperature on growth performance, nitrogen retention, and hindgut’s inflammatory status and bacterial populations in a calf model. Journal of Dairy Research 84, 355–359.CrossRefGoogle Scholar
Bartlett, KS, McKeith, FK, VandeHaar, MJ, Dahl, GE and Drackley, JK 2006. Growth and body composition of dairy calves fed milk replacers containing different amounts of protein at two feeding rates. Journal of Animal Science 84, 1454–1467.CrossRefGoogle ScholarPubMed
Bruck, WM, Graverholt, G and Gibson, GR 2003. A two-stage continuous culture system to study the effect of supplemental alpha-lactalbumin and glycomacropeptide on mixed cultures of human gut bacteria challenged with enteropathogenic Escherichia coli and Salmonella serotype Typhimurium. Journal of Applied Microbiology 95, 44–53.CrossRefGoogle Scholar
School of Veterinary Medicine, University of Wisconsin, Madison 2017. Calf Health Scoring, Chart prepared by the School of Veterinary Medicine, University of Wisconsin, Madison. Retrieved on 11 January 2017 from http://www.vetmed.wisc.edu/dms/fapmtools/8calf/calf_health_scoring_chart.pdf.Google Scholar
Chen, Q, Jinyi, C, Yuchen, J, Xueji, L, Yali, Y and Guangchang, P 2012. Modulation of mice fecal microbiota by administration of casein glycomacropeptide. Microbiology Research 3, 8–12.CrossRefGoogle Scholar
Claud, EC, Lu, L, Anton, PM, Savidge, T, Walker, WA and Cherayil, BJ 2004. Developmentally regulated IkappaB expression in intestinal epithelium and susceptibility to flagellin-induced inflammation. Processing of National Academic Science USA 101, 7404–7408.CrossRefGoogle ScholarPubMed
Davis Rincker, LE, Vandehaar, MJ, Wolf, CA, Liesman, JS, Chapin, LT and Weber Nielsen, MS 2011. Effect of intensified feeding of heifer calves on growth, pubertal age, calving age, milk yield, and economics. Journal of Dairy Science 94, 3554–3567.CrossRefGoogle ScholarPubMed
De Simone, C, Ciardi, A, Grassi, A, Lambert Gardini, S, Tzantzoglou, S, Trinchieri, V, Moretti, S and Jirillo, E 1992. Effect of Bifidobacterium bifidum and Lactobacillus acidophilus on gut mucosa and peripheral blood B lymphocytes. Immunopharmacology and Immunotoxicology 14, 331–340.CrossRefGoogle ScholarPubMed
Gifford, CA, Holland, BP, Mills, RL, Maxwell, CL, Farney, JK, Terrill, SJ, Step, DL, Richards, CJ, Burciaga Robles, LO and Krehbiel, CR 2012. Growth and development symposium: impacts of inflammation on cattle growth and carcass merit. Journal of Animal Science 90, 1438–1451.CrossRefGoogle ScholarPubMed
Hakansson, A and Goran, M 2011. Gut microbiota and inflammation. Nutrients Journal 3, 637–682.CrossRefGoogle ScholarPubMed
Hammon, HM, Schiessler, G, Nussbaum, A and Blum, JW 2002. Feed intake patterns, growth performance, and metabolic and endocrine traits in calves fed unlimited amounts of colostrum and milk by automate, starting in the neonatal period. Journal of Dairy Science 85, 3352–3362.CrossRefGoogle Scholar
Jasper, J and Weary, DM 2002. Effects of ad libitum milk intake on dairy calves. Journal of Dairy Science 85, 3054–3058.CrossRefGoogle ScholarPubMed
Johnson, RW 1997. Inhibition of growth by pro-inflammatory cytokines: an integrated view. Journal of Animal Science 75, 1244–1255.CrossRefGoogle ScholarPubMed
Khan, MA, Lee, HJ, Lee, WS, Kim, HS, Kim, SB, Ki, KS, Ha, JK, Lee, HG and Choi, YJ 2007. Pre- and postweaning performance of Holstein female calves fed milk through step-down and conventional methods. Journal of Dairy Science 90, 876–885.CrossRefGoogle ScholarPubMed
Kinsbergen, M, Bruckmaier, RM and Blum, JW 1994. Metabolic, endocrine and haematological responses to intravenous E. coli endotoxin administration in 1-week-old calves. Zentralblatt fur VeterinarmedizinReihe A 41, 530–547.CrossRefGoogle ScholarPubMed
Larson, LL, Owen, FG, Albrigh, JL, Appleman, RD, Lamb, RC and Muller, LD 1977. Guidelines toward more uniformity in measuring and reporting calf experimental data. Journal of Dairy Science 60, 989–991.CrossRefGoogle Scholar
Lei, YM, Nair, L and Alegre, ML 2015. The interplay between the intestinal microbiota and the immune system. Clinics and Research in Hepatology and Gastroenterology 39, 9–19.CrossRefGoogle ScholarPubMed
Malmuthuge, N, Griebel, PJ and Guan, LL 2015. The Gut microbiome and its potential role in the development and function of newborn calf gastrointestinal tract. Frontier in Veterinary Science 2, 1–22.Google ScholarPubMed
Oikonomou, G, Teixeira, AGV, Foditsch, C, Bicalho, ML, Machado, VS and Bicalho, RC 2013. Fecal microbial diversity in pre-weaned dairy calves as described by pyrosequencing of metagenomic 16S rDNA. Associations of faecalibacterium species with health and growth. PLoS One 8, e63157.CrossRefGoogle Scholar
Otomaru, K, Wataya, K, Uto, T and Kasai, K 2016. Blood biochemical values in Japanese Black calves in Kagoshima Prefecture, Japan. The Journal of Veterinary Medical Science 78, 301–303.CrossRefGoogle Scholar
Pacheco, AR, Barile, D, Underwood, MA and Mills, DA 2015. The impact of the milk glycobiome on the neonate gut microbiota. Annual Review of Animal Bioscience 3, 419–445.CrossRefGoogle ScholarPubMed
Raeth-Knight, M, Chester-Jones, H, Hayes, S, Linn, J, Larson, R, Ziegler, D, Ziegler, B and Broadwater, N 2009. Impact of conventional or intensive milk replacer programs on Holstein heifer performance through six months of age and during first lactation. Journal of Dairy Science 92, 799–809.CrossRefGoogle ScholarPubMed
Rakoff-Nahoum, S, Paglino, J, Eslami-Varzaneh, F, Edberg, S and Medzhitov, R 2004. Recognition of commensal microflora by toll-like receptors is required for intestinal homeostasis. Cell Journal 118, 229–241.CrossRefGoogle ScholarPubMed
Ripamonti, B, Tirloni, E, Stella, S, Bersani, C, Agazzi, A, Maroccolo, S and Savoini, G 2013. Effects of a species-specific probiotic formulation on multiresistant Escherichia coli isolates from the gut of veal calves. Czech Journal of Animal Science 58, 201–207.CrossRefGoogle Scholar
Sanders, ER 2012. Aseptic laboratory techniques: plating methods. Journal of Visualized Experiments 63, 3064.Google Scholar
Schäff, CT, Gruse, J, Maciej, J, Mielenz, M, Wirthgen, E, Hoeflich, A, Schmicke, M, Pfuhl, R, Jawor, P, Stefaniak, T and Hammon, HM 2016. Effects of feeding milk replacer ad libitum or in restricted amounts for the first five weeks of life on the growth, metabolic adaptation, and immune status of newborn calves. PLoS One 11, e0168974.CrossRefGoogle ScholarPubMed
Tang, XS, Shao, H, Li, TJ, Tang, ZR, Huang, RL, Wang, SP, Kong, XF, Wu, X and Yin, YL 2012. Dietary supplementation with bovine lactoferrampin- lactoferricin produced by Pichia pastoris fed-batch fermentation effects intestinal microflora in weaned piglets. Applied Biochemistry and Biotechnology 168, 887–898.CrossRefGoogle ScholarPubMed
Turan, S, Topcu, B, Gökçe, I, Güran, T, Atay, Z, Omar, A, Akçay, T and Bereket, A 2011. Serum alkaline phosphatase levels in healthy children and evaluation of alkaline phosphatase z-scores in different types of rickets. Journal of Clinical Research in Pediatric Endocrinology 3, 7–11.CrossRefGoogle ScholarPubMed
Vandeputte, D, Tito, RY, Vanleeuwen, R, Falony, G and Raes, J 2017. Practical considerations for large-scale gut microbiome studies. FEMS Microbiology Reviews 41, S154–S167.Google ScholarPubMed
Van Soest, PJ, Robertson, JB and Lewis, BA 1991. Methods for dietary fiber, neutral detergent fiber and non-starch polysaccharides in relation to animal nutrition. Journal of Dairy Science 74, 3583–3597.CrossRefGoogle Scholar
Yamauchi, K, Tomita, M, Giehl, TJ and Ellison, RT 1993. Antibacterial activity of lactoferrin and a pepsin-derived lactoferrin peptide fragment. Infection and Immunity 61, 719–728.CrossRefGoogle Scholar
Yun, CH, Wynn, P and Ha, JK 2014. Stress, acute phase proteins and immune modulation in calves. Animal Production Science 54, 1561–1568.CrossRefGoogle Scholar
Zhao, T, Doyle, MP, Harmon, BG, Brown, CA, Mueller, PO and Parks, AH 1998. Reduction of carriage of enterohemorrhagic Escherichia coli O157:H7 in cattle by inoculation with probiotic bacteria. Journal of Clinical Microbiology 36, 641–647.CrossRefGoogle ScholarPubMed