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Effects of dietary molybdenum, sulfur and zinc on the excretion and tissue accumulation of trace elements in sheep fed palm kernel cake-based diets

Published online by Cambridge University Press:  10 May 2011

R. A. Al-Kirshi ,
A. R. Alimon  and
M. Ivan
R. A. Al-Kirshi*
Affiliation:
Institute of Tropical Agriculture, University Putra Malaysia, 43400 UPM Serdang, Selangor, Malaysia
A. R. Alimon
Affiliation:
Institute of Tropical Agriculture, University Putra Malaysia, 43400 UPM Serdang, Selangor, Malaysia
M. Ivan*
Affiliation:
Institute of Tropical Agriculture, University Putra Malaysia, 43400 UPM Serdang, Selangor, Malaysia
*
†E-mail: [email protected]
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Abstract

Twelve male 8-month-old lambs were used in a 6-month feeding experiment to determine the effects of dietary Mo, Mo + S and Zn supplements on the body retention and tissue accumulation of dietary Cu, Zn and Fe. The lambs were divided into four groups of three lambs each and each group was fed ad libitum one of four diets. A control diet was based on palm kernel cake (PKC) and grass hay. Three additional diets were the control supplemented with either Mo or Mo + S or Zn. At 3 months of the experiment, feces and urine were collected and sampled for 6 days. At the end of the experiment (6 months), blood was sampled and then the sheep were slaughtered. The liver and kidney were removed and sampled for chemical analysis. In comparison with the control, each dietary supplement decreased (P < 0.05) the Cu concentration in the liver, but only the Mo + S supplement decreased it to a safe range of below 350 μg/g dry matter. This was accompanied by the body retention of dietary Cu of 24.6%, 6.7%, 2.5% and 6.5% for the control, Mo, Mo + S and Zn treatments, respectively. The blood plasma concentration of Cu was decreased (P < 0.05) by the Zn supplement, but was not affected by other supplements (P > 0.05). It was concluded that from the supplements tested, only Mo + S appeared to be effective in reducing the retention and liver accumulation of the dietary Cu to prevent chronic Cu toxicity in sheep fed PKC-based diets.

Keywords

palm kernel cakesheepmineral excretiontissue accumulation
Type
Full Paper
Information
animal , Volume 5 , Issue 10 , 26 August 2011 , pp. 1539 - 1545
Copyright
Copyright © The Animal Consortium 2011

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References

Alimon, AR, Ivan, M, Jalaludin, S 2011. Effects of different levels of dietary sulfur and molybdenum on concentrations of copper and other elements in plasma and liver of lambs fed palm kernel cake diets. British Journal of Nutrition (in press).Google Scholar
Bremner, I, Marshall, RB 1974. Hepatic copper and zinc biding proteins in ruminants. 2. Relationship between Cu and Zn concentrations and the occurrence of methallothionein-like fraction. British Journal of Nutrition 32, 293–300.CrossRefGoogle Scholar
Bremner, I, Young, BW, Mills, CF 1976. Protective effects of zinc supplementation against copper toxicosis in sheep. British Journal of Nutrition 36, 551–561.CrossRefGoogle ScholarPubMed
Coup, MR, Campbell, AG 1964. The effect of excessive iron intake upon the health and production of dairy cows. New Zealand Journal of Agricultural Research 7, 624–638.Google Scholar
du Plessis, SS, van Niekerk, FE, Coetzer, WA 1999. The effect of dietary molybdenum and sulphate on the oestrus cycle and ovulation in ewes after manipulation with exogenous progesterone alone or in combination with FSH and LH. Small Ruminant Research 33, 63–69.Google Scholar
Dick, AT 1954. Studies on the assimilation and storage of copper in crossbred sheep. Australian Journal of Agricultural Research 5, 511–544.Google Scholar
Gooneratne, SR, Howell, JMcC, Gawthorne, JM 1981. Intravenous administration of thiomolybdate for the prevention of copper poisoning in sheep. British Journal of Nutrition 46, 457–467.Google Scholar
Hair-Bejo, M, Alimon, AR 1992. Hepatic damages and the protective role of zinc and molybdate in palm kernel cake (PKC) toxicity in sheep. Proceedings of the 15th Malaysian Society of Animal Production Conference, Malaysia, pp. 93–95.Google Scholar
Haywood, S, Dincer, Z, Jasani, B, Loughran, MJ 2004. Molybdenum-associated pituitary endocrinopathy in sheep treated with ammonium tetratiomolybdate. Journal of Comparative Pathology 130, 21–31.CrossRefGoogle Scholar
Hidiroglou, M, Heaney, DP, Hartin, KE 1984. Copper poisoning in a flock of sheep. Copper excretion patterns after treatment with molybdenum and sulfur or penicillamine. Canadian Veterinary Journal 25, 377–382.Google Scholar
Hidiroglou, M, Dukes, TW, Ho, SK, Heaney, DP 1978. Bent-limb syndrome in lambs raised in total confinement. Journal of American Veterinary Association 173, 1571–1574.Google Scholar
Hogan, KG, Money, DFL, Blayney, A 1968. The effect of molybdate and sulphate supplement on the accumulation of copper in the livers of penned sheep. New Zealand Journal of Agricultural Research 11, 435–444.CrossRefGoogle Scholar
Ivan, M 1988. Effect of faunation on ruminal solubility and liver content of copper in sheep fed low or high copper diets. Journal of Animal Science 66, 1496–1501.Google Scholar
Ivan, M 1989. Effects of faunation and type of dietary protein on gastric solubility and liver content of copper in sheep. Journal of Animal Science 67, 3028–3035.Google Scholar
Ivan, M, Entz, T 2007. Comparison of effects of Isotricha monofauna and total mixed fauna on dietary copper metabolism in lambs. Canadian Journal of Animal Science 87, 401–405.Google Scholar
Ivan, M, Veira, DM, Kelleher, CA 1986. The alleviation of chronic copper toxicity in sheep by ciliate protozoa. British Journal of Nutrition 55, 361–367.Google Scholar
Ivan, M, Dayrell, M deS, Hidiroglou, M 1992. Effects of bentonite and monensin on selected elements in the stomach and liver of fauna-free and faunated sheep. Journal of Dairy Science 75, 201–209.CrossRefGoogle ScholarPubMed
Ivan, M, Neill, L, Alimon, R, Jalaludin, S 2001a. Effects of bentonite on rumen fermentation and duodenal flow of dietary components in sheep fed palm kernel cake by-product. Animal Feed Science and Technology 92, 127–135.Google Scholar
Ivan, M, Mir, PS, Koenig, KM, Rode, LM, Neill, L, Entz, T, Mir, Z 2001b. Effects of dietary sunflower seed oil on protozoal population in the rumen, growth, and the tissue concentration of fatty acids including conjugated linoleic acid in sheep. Small Ruminant Research 41, 215–227.CrossRefGoogle Scholar
Ivan, M, Entz, T, Mir, PS, Mir, Z, McAllister, TA 2003. Effects of the dietary sunflower seed supplementation and different dietary protein concentrations on the ciliate protozoa population dynamics in the rumen of sheep. Canadian Journal of Animal Science 83, 809–817.CrossRefGoogle Scholar
Ivan, M, Rusihan, M, Alimon, AR, Hair-Bejo, M, Jelan, ZA, Jalaludin, S 1999. The efficacy of dietary supplements of bentonite and sulphur plus molybdenum to alleviate chronic copper toxicity in sheep fed palm kernel cake. Czech Journal of Animal Science 44, 125–130.Google Scholar
Jalaludin, S 1995. Feeding systems based on palm oil products and by-products. In Animal science and development: moving towards a new century (ed. M Ivan), pp. 295–306. Centre for Food and Animal Research, Ottawa, Canada.Google Scholar
Jalaludin, S, Jelan, ZA, Abdulah, N, Ho, YW 1991. Recent developments in the oil palm by-product based ruminant feeding system. Proceedings of the 3rd International Symposium on Nutrition of Herbivores, Malaysia, pp. 35–44.Google Scholar
Jin, LZ, Alimon, AR, Abdulah, N, Ho, YW, Jalaludin, S 1995. Minerals released from palm kernel cake (PKC) and corn-soybean concentrate+copper in the rumen of goats. Malaysian Journal of Animal Science 1, 41–44.Google Scholar
Mason, J, Lamand, M, Fressol, JC, Mulryan, G 1988. Studies of the change in systemic copper metabolism and excretion produced by the intravenous administration of thiomolybdate in sheep. British Journal of Nutrition 59, 289–300.Google Scholar
Ott, EA, Smith, WH, Harrington, RB, Beeson, WM 1966. Zinc toxicity in ruminants. I. Effect of high levels of dietary zinc on gains, feed consumption and feed efficiency of lambs. Journal of Animal Science 25, 414–418.CrossRefGoogle Scholar
Phillipo, M, Humphries, WR, Gathwaite, PH 1987. The effect of dietary molybdenum and iron on cupper status and growth of cattle. Journal of Agricultural Science, Cambridge 109, 315–320.Google Scholar
Rahman, AMY, Wong, HK, Zaini, H, Sharif, H 1989. Preliminary observation on the alleviation of copper in sheep fed with palm kernel meal based diet. Proceedings of 12th Malaysian Society of Animal Production Conference, Malaysia, pp. 75–78.Google Scholar
Ross, DB 1966. The diagnosis, prevention and treatment of chronic copper poisoning in housed lambs. British Veterinary Journal 122, 279–284.Google Scholar
Ross, DB 1970. The effect of oral ammonium molybdate and sodium sulphate given to lambs with high liver copper concentrations. Research in Veterinary Science 11, 295–297.Google Scholar
SAS Institute 2004. SAS user's guide. SAS Institute Inc., Cary, NC, USA.Google Scholar
Suttle, NF 1974. Effects of organic and inorganic sulphur on the availability of dietary copper to sheep. British Journal of Nutrition 32, 559–568.CrossRefGoogle ScholarPubMed
Suttle, NF 1975. The role of organic sulphur in the copper-molybdenum-S interrelationship in ruminant nutrition. British Journal of Nutrition 34, 411–420.Google Scholar
Suttle, NF 2010. Mineral nutrition of livestock. CABI Publishing, Wallington, UK.Google Scholar
Underwood, EJ, Suttle, NF 1999. The mineral nutrition of livestock, 3rd edition. CABI Publishing, Wallington, UK.Google Scholar
van Soest, PJ, Robertson, JB, Lewis, BA 1991. Methods for dietary fiber, neutral detergent fiber, and monostarch polysaccharides in relation to animal nutrition. Journal of Dairy Science 74, 3583–3597.Google Scholar
Wooliams, JA, Suttle, NF, Weiner, G, Field, AC, Wooliams, C 1982. The effect of breed of sire on the accumulation of copper in lambs with particular reference to copper toxicity. Animal Production 35, 299–307.Google Scholar