Hostname: page-component-cd9895bd7-gbm5v Total loading time: 0 Render date: 2024-12-26T18:10:52.147Z Has data issue: false hasContentIssue false
  • English
  • Français

Effects of dietary chromium supplementation on glucose tolerance and primary antibody response against pestedespetitsruminants in dwarf Bengal goats (Capra hircus)

Published online by Cambridge University Press:  15 October 2008

S. Haldar ,
S. Mondal ,
S. Samanta  and
T. K. Ghosh
S. Haldar*
Affiliation:
Department of Animal Nutrition, Faculty of Veterinary and Animal Sciences, West Bengal University of Animal and Fishery Sciences, 37 Kshudiram Bose Sarani, Kolkata 700037, West Bengal, India
S. Mondal
Affiliation:
Department of Animal Nutrition, Faculty of Veterinary and Animal Sciences, West Bengal University of Animal and Fishery Sciences, 37 Kshudiram Bose Sarani, Kolkata 700037, West Bengal, India
S. Samanta
Affiliation:
Department of Animal Nutrition, Faculty of Veterinary and Animal Sciences, West Bengal University of Animal and Fishery Sciences, 37 Kshudiram Bose Sarani, Kolkata 700037, West Bengal, India
T. K. Ghosh
Affiliation:
Department of Animal Nutrition, Faculty of Veterinary and Animal Sciences, West Bengal University of Animal and Fishery Sciences, 37 Kshudiram Bose Sarani, Kolkata 700037, West Bengal, India
*
E-mail: [email protected]
Get access

Abstract

An experiment was conducted to exploit the immune-modulation effect of trivalent chromium (Cr) for augmenting immunity against peste des petits ruminants (PPR) in dwarf black Bengal goats (Capra hircus). The goats (n = 6 per treatment group) either received a basal diet devoid of supplemental Cr (control) or were supplemented with 0.5 mg Cr as chromic chloride (+Cr) for 60 days. Live weight gain and feed conversion efficiency improved (P < 0.05) in the +Cr dietary group. Supplemental Cr did not affect the total number of monocytes, eosinophils and basophils (P > 0.1) although total leukocytes increased (P < 0.05) and the ratio of neutrophils to lymphocytes narrowed down (P < 0.05) in the +Cr dietary group. The effect of Cr supplementation on variables of the intravenous glucose tolerance test (IVGTT) was inconclusive. Compared to the control group, the basal concentration of glucose (P < 0.05) and insulin (P < 0.001) was higher, clearance rate was slower (P < 0.05) and serum half-life was greater (P < 0.05) in the +Cr dietary group during the IVGTT. Over the duration of the experiment, serum concentration of insulin increased (P < 0.001) and that of cortisol decreased (P < 0.01) in the +Cr group, which also showed a relatively higher primary antibody (Ab) response against PPR on days 10 (P < 0.01) and 20 (P < 0.05) post-vaccination. In conclusion, the experiment indicated that supplementation of Cr as CrCl3, in the diet of non-stressed goats, may improve primary Ab response against PPR and help confer an augmented immunity to the disease besides promoting growth and feed conversion.

Keywords

chromiumglucose tolerancegrowthimmunitypeste de petits ruminants
Type
Full Paper
Information
animal , Volume 3 , Issue 2 , February 2009 , pp. 209 - 217
Copyright
Copyright © The Animal Consortium 2008

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Ahmed, N, Haldar, S, Pakhira, MC, Ghosh, TK 2005. Growth performance, nutrient utilization and carcass traits in broiler chickens fed with a normal and a low energy diet supplemented with inorganic chromium (as chromic chloride hexahydrate) and a combination of inorganic chromium and ascorbic acid. Journal of Agricultural Science 143, 427–439.CrossRefGoogle Scholar
Amatya, JL, Haldar, S, Ghosh, TK 2004. Effects of chromium supplementation from inorganic and organic sources on nutrient utilization, mineral metabolism and meat quality in broiler chickens exposed to natural heat stress. Animal Science 79, 241–253.CrossRefGoogle Scholar
Association of Official and Analytical Chemists 1995. Official methods of analysis, 16th edition. AOAC, Arlington, VA, USA.Google Scholar
Biswas, P, Haldar, S, Pakhira, MC, Ghosh, TK, Biswas, C 2006. Efficiency of nutrient utilization and reproductive performances of pre pubertal anestrous dairy heifers supplemented with inorganic and organic chromium compounds. Journal of the Science of Food and Agriculture 86, 804–815.CrossRefGoogle Scholar
Borel, JS, Majeres, TC, Polansky, M, Moser, PB, Anderson, RA 1984. Chromium intake and urinary chromium excretion of trauma patients. Biological Trace Element Research 6, 317–321.CrossRefGoogle ScholarPubMed
Borgs, P, Mallard, BA 1998. Immune-endocrine interactions in agricultural species: chromium and its on health and performance. Domestic Animal Endocrinology 15, 431–438.CrossRefGoogle ScholarPubMed
Bunting, LD, Fernandez, JM, Thompson, DL, Southern, LL 1994. Influence of chromium picolinate on glucose usage and metabolic criteria in growing Holstein calves. Journal of Animal Science 72, 1591–1599.CrossRefGoogle ScholarPubMed
Bunting, LD, Tarifa, TA, Crochet, BT, Fernandez, JM, DePew, CL, Lovejoy, JC 2000. Effects of dietary inclusion of chromium picolinate and calcium propionate on glucose disposal and gastrointestinal development in dairy cows. Journal of Dairy Science 83, 2491–2498.CrossRefGoogle Scholar
Burton, JL 1995. Supplemental chromium: its benefit to the bovine immune system. Animal Feed Science and Technology 53, 117–133.CrossRefGoogle Scholar
Burton, JL, Mallard, BA, Mowat, DN 1993. Effects of supplemental chromium on immune responses of periparturient and early lactation dairy cows. Journal of Animal Science 71, 1532–1539.CrossRefGoogle ScholarPubMed
Burton, JL, Mallard, BA, Mowat, DN 1994. Effects of supplemental chromium on antibody response of newly weaned feedlot calves to immunization with infectious bovine rhinotracheitis and parainfluenza 3 virus. Canadian Journal of Veterinary Research 58, 148–151.Google ScholarPubMed
Chang, X, Mowat, DN 1992. Supplemental chromium for stressed and growing feeder calves. Journal of Animal Science 70, 559–565.CrossRefGoogle ScholarPubMed
Chang, X, Mallard, BA, Mowat, DN 1994. Proliferation of peripheral blood lymphocytes of feeder calves in response to chromium. Nutrition Research 58, 148–151.Google Scholar
Chang, X, Mallard, BA, Mowat, DN 1996. Effects of chromium on health status, blood neutrophil phagocytosis and in vitro lymphocyte blastogenesis of dairy cows. Veterinary Immunology and Immunopathology 52, 37–52.CrossRefGoogle ScholarPubMed
Friend, TH, Dellmeier, GR, Gbur, EE 1985. Comparison of four methods of calf confinement. Journal of Physiology 60, 1095–2000.Google ScholarPubMed
Gentry, LR, Fernandez, JM, Ward TL White, TW, Southern, LL, Bidner, TD, Thompson, DL Jr, Horohov, DW, Chapa, AM, Sahlu, T 1999. Dietary protein and chromium tripicolinate in Suffolk Weather lambs: effects on production characteristics, metabolite and hormonal responses and immune status. Journal of Animal Science 77, 1284–1294.CrossRefGoogle Scholar
Haldar, S, Ghosh, TK, Pakhira, MC, De, K 2006. Effects of incremental dietary chromium (Cr3+) on growth, hormone concentrations and glucose clearance in growing goats (Capra hircus). Journal of Agricultural Science 144, 269–280.CrossRefGoogle Scholar
Haldar, S, Samanta, S, Banarjee, R, Sharma, B, Ghosh, TK 2007. Glucose tolerance and serum concentrations of hormones and metabolites in goats (Capra hircus) fed diets supplemented with inorganic and organic chromium salts. Animal 1, 247–256.CrossRefGoogle ScholarPubMed
Kahn, CR 1978. Insulin resistance, insulin insensitivity and insulin unresponsiveness: a necessary distinction. Metabolism 27, 1893–1902.CrossRefGoogle ScholarPubMed
Kaneko, JJ, Harvey, JW, Bruss, ML 1997InClinical biochemistry of domestic animals (ed. JJ Kaneko), pp. 890–894. Academic Press, New York, USA.Google Scholar
Kegley, EB, Spears, JW, Brown, TT 1997. Effect of shipping and chromium supplementation on performance, immune response, and disease resistance of steers. Journal of Animal Science 75, 1956–1964.CrossRefGoogle ScholarPubMed
Kitchalong, L, Fernandez, JM, Bunting, LD, Southern, LL, Bidner, TD 1995. Influence of chromium tripicolinate on glucose metabolism and nutrient partitioning in growing lambs. Journal of Animal Science 73, 2694–2705.CrossRefGoogle ScholarPubMed
Mertz, W 1993. Chromium in human nutrition: a review. Journal of Nutrition 123, 626–633.CrossRefGoogle ScholarPubMed
Moonsie-Shageer, S, Mowat, DN 1993. Effect of level of supplemental chromium on performance, serum constituents, and immune status of stressed feeder calves. Journal of Animal Science 71, 232–238.CrossRefGoogle ScholarPubMed
Mordenti, A, Piva, A, Piva, G 1997. The European perspective on organic chromium in animal nutrition. In Biotechnology in the Feed Industry: Proceedings of Alltech’s 13th Annual Symposium (ed. TP Lyons and KA Jacques), pp. 227–240. Nottingham University Press, Nottingham, UK.Google Scholar
Mowat, DN, Chang, X, Yang, YZ 1993. Chelated chromium for stressed feeder calves. Canadian Journal of Animal Science 73, 49–55.CrossRefGoogle Scholar
National Research Council 1981. Nutrient requirement of goats: Angora, dairy and meat goats in temperate and tropical countries. NRC, National Academy Press, Washington, D.C., USA.Google Scholar
Paul, TK, Haldar, S, Ghosh, TK 2005. Growth performance and nutrient utilization in black Bengal bucks (Capra hircus) supplemented with graded doses of chromium as chromium chloride hexahydrate. Journal of Veterinary Science 6, 33–40.CrossRefGoogle ScholarPubMed
Pechova, A, Pavlata, L 2007. Chromium as an essential nutrient: a review. Veterinarni Medicina 52, 1–18.CrossRefGoogle Scholar
Sano, H, Nakai, M, Kondo, T, Terashima, Y 1991. Insulin responsiveness to glucose and tissue responsiveness to insulin in lactating, pregnant, and non pregnant, non-lactating beef cows. Journal of Animal Science 69, 1122–1127.CrossRefGoogle Scholar
Singh, RP, Bandopadhyay, SK, Sreenivasa, BP, Dhar, P 2004a. Production and characterization of monoclonal antibodies to peste de petits ruminants (PPR) virus. Veterinary Research Communication 28, 623–639.CrossRefGoogle Scholar
Singh, RP, Sreenivasa, BP, Dhar, P, Shah, LC, Bandopadhyay, SK 2004b. Development of a monoclonal antibody based competitive ELISA for detection and titration of antibodies of peste de petits ruminants (PPR) virus. Veterinary Microbiology 98, 3–15.CrossRefGoogle Scholar
Striffler, SS, Polansky, MM, Anderson, RA 1993. Dietary chromium enhances insulin secretion in perfused rat pancreas. Journal of Trace Elements in Experimental Medicine 6, 75–81.Google Scholar
Subiyatno, A, Mowat, DN, Yang, WZ 1996. Metabolite and hormonal responses to glucose or propionate infusions in periparturient dairy cows supplemented with chromium. Journal of Dairy Science 79, 1436–1445.CrossRefGoogle ScholarPubMed
Swanson, KC, Harmon, DL, Jacques, KA, Larson, BT, Richards, CJ, Bohnert, DW, Paton, SJ 2000. Efficacy of chromium-yeast supplementation for growing beef steers. Animal Feed Science and Technology 86, 95–105.CrossRefGoogle Scholar
Van Soest, PJ, Robertson, JB, Lewis, BA 1991. Methods for dietary fiber, neutral detergent fiber and non-starch polysaccharides in relation to animal nutrition. Journal of Dairy Science 74, 3583–3597.CrossRefGoogle Scholar
Vincent, JB 2000. The biochemistry of chromium. Journal of Nutrition 130, 715–718.CrossRefGoogle ScholarPubMed