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Assessment of a natural dietary extract, titrated in phenylpropanoid glycosides, on blood parameters and plasma oxidative status in intensively reared Italian hares (Lepus corsicanus)

Published online by Cambridge University Press:  14 January 2011

M. Palazzo ,
F. Vizzarri ,
M. Cinone ,
C. Corino  and
D. Casamassima
M. Palazzo
Affiliation:
Department of Animal Plant and Environmental Science, Faculty of Agriculture, Università degli Studi del Molise, Via De Sanctis, snc, 86100 Campobasso, Italy
F. Vizzarri
Affiliation:
Department of Animal Plant and Environmental Science, Faculty of Agriculture, Università degli Studi del Molise, Via De Sanctis, snc, 86100 Campobasso, Italy
M. Cinone
Affiliation:
Department of Animal Production, Faculty of Veterinary Medicine, Università degli Studi di Bari, Strada provinciale per Casamassima km 3–70010 Valenzano Bari, Italy
C. Corino
Affiliation:
Department of Veterinary Sciences and Technologies for Food Security, Faculty of Veterinary Medicine, Università degli Studi di Milano, Via Celoria, 10–20133 Milano, Italy
D. Casamassima*
Affiliation:
Department of Animal Plant and Environmental Science, Faculty of Agriculture, Università degli Studi del Molise, Via De Sanctis, snc, 86100 Campobasso, Italy
*
†E-mail: [email protected]
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Abstract

Two different doses of a natural extract titrated in phenylpropanoid glycosides (PPGs) were evaluated for their effect on blood parameters and plasma oxidative status in pairs of intensively reared Italian hares. The study lasted 210 days, during which 45 couples of hares were divided into three homogeneous groups. A control group (CON) was fed a control diet while the two experimental groups were fed a diet supplemented with 1 or 2 kg/t of a supplement titrated in PPGs. Blood samples were obtained at 0, 70, 140 and 210 days and assayed for plasma lipid profiles, bilirubin, haematological parameters and indicators of oxidative status (reactive oxygen metabolites (ROMs), thiobarbituric acid reactive substances (TBARS), vitamins A and E). Although dietary treatment did affect the levels of triglycerides, total cholesterol and total bilirubin, all of which decreased markedly (P < 0.05), while significantly increasing the (P < 0.01) HDL cholesterol values, it also significantly improved the oxidative status of the blood, which displayed an increase in both vitamin E (P < 0.01) and vitamin A (P < 0.05) and a decrease in ROMs (P < 0.01) and TBARS (P < 0.05). The improvements in the blood parameters, lipid profile and plasma oxidative status continued to increase significantly as the trial progressed, indicating a positive effect with increased length of treatment. The results of this study demonstrate an important role for feed supplementation with respect to antioxidant activity on some blood parameters, including the lipid profile and the oxidative status of blood.

Keywords

natural extractsverbascosideblood parametershare
Type
Full Paper
Information
animal , Volume 5 , Issue 6 , June 2011 , pp. 844 - 850
Copyright
Copyright © The Animal Consortium 2011

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