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Immune responses, intestinal microbiota, performance and blood characteristics of Japanese quail fed on diets containing camphor

Published online by Cambridge University Press:  23 May 2017

A. Sedaghat  and
M. A. Karimi Torshizi
A. Sedaghat
Affiliation:
Department of Poultry Science, College of Agriculture, Tarbiat Modares University, PO Box 14115-336, Tehran, Iran
M. A. Karimi Torshizi*
Affiliation:
Department of Poultry Science, College of Agriculture, Tarbiat Modares University, PO Box 14115-336, Tehran, Iran
*
†E-mail: [email protected]
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Abstract

This study aimed to investigate the effect of supplemental camphor on the performance and immune functions of Japanese quail by feeding graded levels (0 (control), 250, 500, 750, 1000, 5000 or 10 000 ppm) of camphor during a 42-day feeding trial. In all, 280 1-day-old quail chicks were randomly assigned into 28 cages of 10 chicks each with separate feeders. The results clearly demonstrated that camphor did not have a significant effect on BW, BW gain, total experimental average daily feed intake, feed conversion ratio, internal organ relative weights and biochemical parameters such as uric acid, albumin, total protein and triglyceride; however, plasma cholesterol concentration was significantly different in a linear manner, in which 500 ppm of camphor resulted in a lower level of cholesterol. Alternatively, greater concentrations of glucose and high-density lipoprotein (HDL) were also found in 5000 and 1000 ppm of camphor groups, respectively. Cellular responses to the phytohaemagglutinin-P and 2,4-dinitro 1-chlorobenzene skin test were not influenced by dietary camphor. Humoral responses to secondary sheep red blood cells, avian influenza virus (AIV) and Newcastle disease virus (NDV) immunisations were positively influenced by camphor supplementation, in which greater secondary response to sheep erythrocytes belonged to 750 and 1000 ppm of camphor groups; whereas, diet supplementation with camphor had no significant effect on lymphoid organ weights and heterophil-to-lymphocyte ratio. The greatest AIV antibody titers were seen in groups, which received 1000 and 5000 ppm of camphor (P<0.05) and the values of NDV antibody titers increased with an increase in the camphor consumption. Furthermore, dietary inclusion of 500 ppm of camphor positively decreased coliform populations in the gastrointestinal tract (GIT). In addition, an increase in lactic acid bacteria was also observed in quails, which were fed on the diets containing 750 ppm camphor. Collectively, these data suggest that as a phytogenic feed additive, camphor may effectively act as a modulator of health status (by increasing glucose and HDL), GIT microbiota and immunological responses of the Japanese quail.

Keywords

blood characteristicscamphorimmune responseintestinal microbiotaJapanese quail
Type
Research Article
Information
animal , Volume 11 , Issue 12 , December 2017 , pp. 2139 - 2146
Copyright
© The Animal Consortium 2017 

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References

Abdullah-Al-Mamun, M, Huque, A, Biswas, S, Bhuiyan, JR and Rashid, MHU 2014. Toxicological studies of Karpura Rasa on the basis of lipid profile, liver function and kidney function in rat plasma after chronic administration. Journal of Chemical and Pharmaceutical Research 6, 122–126.Google Scholar
Abu Taleb, AM, Salah, HM, Ezzat, IE and Barkouky, E 2003. Effect of feeding camphor (Eucalyptus globules) levels on some immunity characteristics, growth and gut microflora of Japanese quails. Isotope and Radiation Research 35, 701–711.Google Scholar
Allen, PC, Lydon, J and Danforth, HD 1997. Effects of components of Artemisia annua on coccidia infections in chickens. Poultry Science 76, 1156–1163.Google Scholar
Ben El Hadj Ali, I, Chaouachi, M, Bahri, R, Chaieb, I, Boussaïd, M and Harzallah-Skhiri, F 2015. Chemical composition and antioxidant, antibacterial, allelopathic and insecticidal activities of essential oil of Thymus algeriensis Boiss. et Reut. Industrial Crops and Products 77, 631–639.Google Scholar
Botsoglou, NA, Florou-Paneri, P, Christaki, E, Fletouris, DJ and Spais, AB 2002. Effect of dietary oregano essential oil on performance of chickens and on iron-induced lipid oxidation of breast, thigh and abdominal fat tissues. British Poultry Science 43, 223–230.Google Scholar
Brenes, A and Roura, E 2010. Essential oils in poultry nutrition: main effects and modes of action. Animal Feed Science and Technology 158, 1–14.Google Scholar
Carou, ME, Deguiz, ML, Reynoso, R, Szwarcfarb, B, Carbone, S, Moguilevsky, Ja, Scacchi, P and Ponzo, OJ 2009. Impact of the UV-B filter 4-(Methylbenzylidene)-camphor (4-MBC) during prenatal development in the neuroendocrine regulation of gonadal axis in male and female adult rats. Environmental Toxicology and Pharmacology 27, 410–414.Google Scholar
Chen, W, Vermaak, I and Viljoen, A 2013. Camphor – a fumigant during the black death and a coveted fragrant wood in ancient Egypt and Babylon – a review. Molecules 18, 5434–5454.Google Scholar
Cherneva, E, Pavlovic, V, Smelcerovic, A and Yancheva, D 2012. The effect of camphor and borneol on rat thymocyte viability and oxidative stress. Molecules 17, 10258–10266.Google Scholar
Cross, DE, McDevitt, RM, Hillman, K and Acamovic, T 2007. The effect of herbs and their associated essential oils on performance, dietary digestibility and gut microflora in chickens from 7 to 28 days of age. British Poultry Science 48, 496–506.CrossRefGoogle ScholarPubMed
Denbow, DM 1991. Induction of food intake by a GABAergic mechanism in the turkey. Physiology and Behavior 49, 485–488.Google Scholar
Denbow, DM, Meade, S, Robertson, A, McMurtry, JP, Richards, M and Ashwell, C 2000. Leptin-induced decrease in food intake in chickens. Physiology and Behavior 69, 359–362.Google Scholar
Dridi, S, Swennen, Q, Decuypere, E and Buyse, J 2005. Mode of leptin action in chicken hypothalamus. Brain Research 1047, 214–223.CrossRefGoogle ScholarPubMed
Engeu, PO, Omujal, F, Agwaya, M, Kyakulaga, H and Obua, C 2015. Variations in antimalarial components of Artemisia annua Linn from three regions of Uganda. African Health Sciences 15, 828–834.Google Scholar
Ertas, ON, Güler, T, Çiftçi, M, Dalkiliç, B and Yilmaz, O 2005. The effect of a dietary supplement coriander seeds on the fatty acid composition of breast. Revue de médecine vétérinaire 156, 514–518.Google Scholar
Guenther, A, Hewitt, CN, Erickson, D, Fall, R, Geron, C, Graedel, T and Zimmerman, P 1995. A global model of natural volatile organic compound emissions. Journal of Geophysical Research 100, 8873–8892.Google Scholar
Hammerschmidt, F, Clark, A, Soliman, F, El-Kashoury, ES, Abd El-Kawy, M and El-Fishawy, A 1993. Chemical composition and antimicrobial activity of essential oils of Jasonia candicans and J. montana . Planta Medica 59, 68–70.Google Scholar
Hashemi, SR and Davoodi, H 2011. Herbal plants and their derivatives as growth and health promoters in animal nutrition. Veterinary Research Communications 35, 169–180.Google Scholar
Helander, IM, Alakomi, HL, Latva-Kala, K, Mattila-Sandholm, T, Pol, I, Smid, EJ, Gorris, LGM and von Wright, A 1998. Characterization of the action of selected essential oil components on Gram-negative bacteria. Journal of Agricultural and Food Chemistry 46, 3590–3595.Google Scholar
Herzog, R and Leuschner, J 1997. Reproductive toxicity studies of benzalazine in rats and rabbits. Arzneimittel-Forschung 44, 1368–1370.Google Scholar
Jamshidzadeh, A, Sajedianfard, J, Nekooeian, AA, Tavakoli, F and Omrani, GH 2006. Effects of camphor on sexual behaviors in male rats. Iranian Journal of Pharmaceutical Sciences 2, 209–214.Google Scholar
Jin, LZ, Ho, YW, Abdullah, N and Jalaludin, S 1998. Growth performance, intestinal microbial populations, and serum cholesterol of broilers fed diets containing Lactobacillus cultures. Poultry Science 77, 1259–1265.Google Scholar
Johari, H, Mahjoor, AA, Fallahi, S, Kargar Jahromi, H, Abedini, M, Poor Danesh, MA and Zamani, Z 2013. Effect of camphor on pituitary-gonadal hormonal axis and oogenesis in adult female rats. Journal of Fasa University of Medical Sciences 3, 69–74.Google Scholar
Jonaidi, H, Babapour, V and Denbow, DM 2002. GABAergic control of food intake in the meat-type chickens. Physiology and Behavior 76, 465–468.Google Scholar
Juteau, F, Masotti, V, Bessière, JM, Dherbomez, M and Viano, J 2002. Antibacterial and antioxidant activities of Artemisia annua essential oil. Fitoterapia 73, 532–535.Google Scholar
Kotan, R, Kordali, S, Cakir, A, Kesdek, M, Kaya, Y and Kilic, H 2008. Antimicrobial and insecticidal activities of essential oil isolated from Turkish Salvia hydrangea DC. ex Benth. Biochemical Systematics and Ecology 36, 360–368.CrossRefGoogle Scholar
Lee, HJ, Hyun, EA, Yoon, WJ, Kim, BH, Rhee, MH, Kang, HK, Cho, JY and Yoo, ES 2006. In vitro anti-inflammatory and anti-oxidative effects of Cinnamomum camphora extracts. Journal of Ethnopharmacology 103, 208–216.CrossRefGoogle ScholarPubMed
Magiatis, P, Skaltsounis, AL, Chinou, I and Haroutounian, SA 2002. Chemical composition and in-vitro antimicrobial activity of the essential oils of three Greek Achillea species. Zeitschrift Für Naturforschung C 57, 287–290.Google Scholar
Michiels, J, Missotten, J, Ovyn, A, Dierick, N, Fremaut, D and De Smet, S 2012. Effect of dose of thymol and supplemental flavours or camphor on palatability in a choice feeding study with piglets. Czech Journal of Animal Science 57, 65–74.Google Scholar
National Research Council (NRC) 1994. Nutrient requirements of poultry, 9th revised edition. National Academy Press, Washington, DC, USA.Google Scholar
Schlumpf, M, Jarry, H, Wuttke, W, Ma, R and Lichtensteiger, W 2004a. Estrogenic activity and estrogen receptor β binding of the UV filter 3-benzylidene camphor. Toxicology 199, 109–120.CrossRefGoogle ScholarPubMed
Schlumpf, M, Schmid, P, Durrer, S, Conscience, M, Maerkel, K, Henseler, M, Gruetter, M, Herzog, I, Reolon, S, Ceccatelli, R, Faass, O, Stutz, E, Jarry, H, Wuttke, W and Lichtensteiger, W 2004b. Endocrine activity and developmental toxicity of cosmetic UV filters – an update. Toxicology 205, 113–122.Google Scholar
Setzer, W 2004. Antimicrobial activity of Artemisia douglasiana leaf essential oil. Fitoterapia 75, 192–200.Google Scholar
Shahabi, S, Jorsaraei, SGA, Moghadamnia, AA, Barghi, E, Zabihi, E, Amiri, MG, Maliji, G, Faraji, AS, Boora, MA and Ghazinejad, N 2014. The effect of camphor on sex hormones levels in rats. Cell Journal (Yakhteh) 16, 231–234.Google Scholar
Xu, H 2005. Camphor activates and strongly desensitizes the transient receptor potential vanilloid subtype 1 channel in a vanilloid-independent mechanism. Journal of Neuroscience 25, 8924–8937.Google Scholar
Zendehdel, M, Baghbanzadeh, A, Babapour, V and Cheraghi, J 2009. The effects of bicuculline and muscimol on glutamate-induced feeding behavior in broiler cockerels. Journal of Comparative Physiology A 195, 715–720.Google Scholar
Zeni, LAZR, Seidler, HBK, De Carvalho, NAS, Freitas, CG, Marino-Neto, J and Paschoalini, MA 2000. Glutamatergic control of food intake in pigeons: effects of central injections of glutamate, NMDA, and AMPA receptor agonists and antagonists. Pharmacology Biochemistry and Behavior 65, 67–74.Google Scholar