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Intra-Abdominal Transmitter Implantation in Mice: Effects on Behaviour and Body Weight

Published online by Cambridge University Press:  11 January 2023

V Baumans ,
J A Bouwknecht ,
H Boere ,
K Kramer ,
H A van Lith ,
H A van de Weerd  and
H van Herck
V Baumans
Affiliation:
Department of Laboratory Animal Science, Veterinary Faculty, Utrecht University, PO Box 80.166, 3508 TD Utrecht, The Netherlands
J A Bouwknecht
Affiliation:
Department of Psychopharmacology, Faculty of Pharmacy, Utrecht University, The Netherlands
H Boere
Affiliation:
Central Laboratory Animal Institute, Utrecht University, The Netherlands
K Kramer
Affiliation:
LACDR, Department of Pharmacochemistry, Free University, Amsterdam, The Netherlands
H A van Lith
Affiliation:
Department of Laboratory Animal Science, Veterinary Faculty, Utrecht University, PO Box 80.166, 3508 TD Utrecht, The Netherlands
H A van de Weerd
Affiliation:
Department of Laboratory Animal Science, Veterinary Faculty, Utrecht University, PO Box 80.166, 3508 TD Utrecht, The Netherlands
H van Herck
Affiliation:
Central Laboratory Animal Institute, Utrecht University, The Netherlands
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Abstract

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Biotelemetry is a useful tool for the simultaneous measurement of several physiological and behavioural parameters in non-restrained, freely moving animals. However, the weight and volume of the implanted intra-abdominal transmitter may cause discomfort. The aim of this study was to assess body weight and behaviour of BALB/c and 129/Sv mice after implantation of an intra-abdominal transmitter. In order to measure more detailed behaviour, the automated behaviour observation analysis system (LABORAS™) was used. During the first days after surgery, body weight and the behaviours of climbing, locomotion and eating were found to decrease in both strains, whereas grooming and immobility increased. These changes were more pronounced in the transmitter animals than in the sham operated animals, however, indicating a temporary impairment in well-being. Within two weeks after surgery, the animals seemed to have fully recovered.

Keywords

micetelemetrytransmitter implantation
Type
Research Article
Information
Animal Welfare , Volume 10 , Issue 3 , August 2001 , pp. 291 - 302
Copyright
© 2001 Universities Federation for Animal Welfare

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