Hostname: page-component-586b7cd67f-dsjbd Total loading time: 0 Render date: 2024-11-23T20:21:52.970Z Has data issue: false hasContentIssue false

In-Homecage Blood Collection from Conscious Stumptailed Macaques

Published online by Cambridge University Press:  11 January 2023

V Reinhardt
Affiliation:
Wisconsin Regional Primate Research Center, 1223 Capitol Court, Madison, WI 53715, USA
D Cowley
Affiliation:
Wisconsin Regional Primate Research Center, 1223 Capitol Court, Madison, WI 53715, USA
Rights & Permissions [Opens in a new window]

Abstract

Core share and HTML view are not available for this content. However, as you have access to this content, a full PDF is available via the ‘Save PDF’ action button.

Six adult female stumptailed macaques (Macaca arctoides) were trained within a two-week period to actively co-operate during in-homecage venipuncture rather than in a restraint apparatus away from the homecage. The training was based on consistent firmness, gentleness and patience. Total training time per subject ranged from 15 to 45 minutes with a mean of 33.5 minutes. Endocrinological analysis one week after the last training session revealed an insignificant increase (0.49%) in serum Cortisol between venipuncture samples taken 15 minutes apart. It was concluded that training stumptailed macaques to actively co-operate during blood collection in their familiar homecage promotes the animals’ well-being by avoiding undue disturbance; increases the validity of research data collected by minimizing distress, and reduces health risks of the handling personnel by eliminating the need to carry the animals to a special area.

Type
Research Article
Copyright
© 1992 Universities Federation for Animal Welfare

References

Bunyak, S C, Harvey, N C, Rhine, R J, Wilson, MI 1982 Venipuncture and vaginal swabbing in an enclosure occupied by a mixed-sex group of stumptailed macaques (Macaca arctoides). American Journal of Primatology 2: 201204CrossRefGoogle Scholar
Clarke, M R, Phillippi, K M, Falkenstein, J A, Moran, E A, Suomi, S J 1990 Training corral-living rhesus monkeys for fecal and blood sample collection. American Journal of Primatology 20: 181Google Scholar
Line, S W, Clarke, S, Markowitz, H 1989a Plasma Cortisol of female rhesus monkeys in response to restraint. Laboratory Primate Newsletter 26(4): 14Google Scholar
Line, S W, Markowitz, H, Morgan, K N, Strong, S 1991 Effects of cage size and environmental enrichment on behavioral and physiological responses of rhesus macaques to the stress of daily events. In Novak, M A, Petto, A J (eds) Through the Looking Glass. Issues of Psychological Well-being in Captive Non-human Primates, pp 160179. American Psychological Association: Washington DCCrossRefGoogle Scholar
Line, S W, Morgan, K N, Markowitz, H, Strong, S 1989b Heart rate and activity of rhesus monkeys in response to routine events. Laboratory Primate Newsletter 28(2): 14Google Scholar
Priest, G M 1991 Training a diabetic drill (Mandrillus leucophaeus) to accept insulin injections and venipuncture. Laboratory Primate Newsletter 30(1): 14Google Scholar
Reinhardt, V 1991a Impact of venipuncture on physiological research conducted in conscious macaques. Journal of Experimental Animal Science 34: 212217Google ScholarPubMed
Reinhardt, V 1991b Training adult male rhesus monkeys to actively cooperate during in-homecage venipuncture. Animal Technology 42: 1117Google Scholar
Reinhardt, V 1992 Low-stress interactions between scientist and rhesus monkey. In Davis, H, Balfour, D (eds) The Inevitable Bond, pp 171177. Cambridge University Press: New YorkGoogle Scholar
Reinhardt, V, Cowley, D 1990 Training stumptailed monkeys to cooperate during in-homecage treatment. Laboratory Primate Newsletter 29(4) 910Google Scholar
Reinhardt, Y, Pape, R, Zweifel, D 1991a Multifunctional cage for macaques housed in pairs or in small groups. AALAS Bulletin 30(5): 1415Google Scholar
Reinhardt, V, Cowley, D, Eisele, S, Scheffler, J 1991b Avoiding undue Cortisol responses to venipuncture in adult male rhesus macaques. Animal Technology 42: 8386Google Scholar
Reinhardt, V, Cowley, D, Scheffler, J, Vertein, R, Wegner, F 1990 Cortisol response of female rhesus monkeys to venipuncture in homecage versus venipuncture in restraint apparatus. Journal of Medical Primatology 19: 601606CrossRefGoogle ScholarPubMed
Siegel, S 1956 Nonparametric Statistics for the Behavioral Sciences. Plenum Press: New YorkGoogle Scholar
Smith, E O 1981 Device for capture and restraint of nonhuman primates. Laboratory Animal Science 32: 305306Google Scholar
Walker, M L, Gordon, T P, Wilson, M E 1982 Reproductive performance in capture-acclimated female rhesus monkeys (Macaca mulatta). Journal of Medical Primatology 11: 291302CrossRefGoogle ScholarPubMed