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Identification of appropriate measures for the assessment of laboratory mouse welfare

Published online by Cambridge University Press:  11 January 2023

MC Leach ,
PD Thornton  and
DCJ Main
MC Leach*
Affiliation:
University of Newcastle upon Tyne, Comparative Biology Centre, Framlington Place, Newcastle upon Tyne NE2 4HH, UK
PD Thornton
Affiliation:
University of Bristol, Department of Clinical Veterinary Science, Langford House, Langford, Bristol BS40 5DU, UK
DCJ Main
Affiliation:
Home Office, Queen Anne's Gate, London SWIH 9AT, UK
*
* Contact for correspondence and requests for reprints: [email protected]
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Abstract

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A Delphi consultation process was used to examine the validity and feasibility of potential resource-input and animal-based outcome measures of laboratory mouse welfare identified by a comprehensive literature search. The consultation was an iterative two-stage technique that used web and email based questionnaires to gather data. On completion of the second consultation stage a total of 97 measures of mouse welfare, their order of importance, and appropriate sample sizes and sampling times where relevant, were identified. Of these, 55 were resource-input measures that included assessments of the cages, animal rooms environmental conditions, husbandry procedures, provision of food and water, staffing, resources placed into mouse cages, and the establishment policies. The remaining 42 were animal-based outcomes, measures that included assessments of unprovoked behaviour, provoked responses, vocalisations, physical appearance, and health indicators. The measures that were considered by the experts to be appropriate for assessing laboratory mouse welfare measures can be placed into four basic categories: characteristics of the staff, performance of husbandry and care procedures, health and well-being of the mice, and the provision and use of cage resources.

Keywords

animal-based outcome measuresanimal welfareDelphi techniqueexpert opinion and refinementlaboratory miceresource-input measures
Type
Articles
Information
Animal Welfare , Volume 17 , Issue 2 , May 2008 , pp. 161 - 170
Copyright
© 2008 Universities Federation for Animal Welfare

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