The expected annual selection response is a function of selection intensity (i), generation interval (t) and precision (p) of breeding value estimation. These three parameters may, under certain conditions, be reduced to functions of one variable, y, the mean age of breeding animals at culling, which is a simple function of the annual replacement rate. When the number of breeding males and females are different, i and t become functions of two variables ym and yf, the mean ages of males and females at culling. The values of y (or of ym and yt) giving the maximum selection response are established for different domestic species: for individual selection, where the ratio i/t is to be maximized, for selection on a repeatable criterion connected to female reproduction (prolificacy, milk or egg production), where the maximum of ip/t is to be determined, and for male progeny-testing. The results show that, the more prolific a species is, the more rapid the renewal of breeding animals must be and that the renewal should be more rapid for males than for females, particularly in species of low prolificacy. When selecting on female performances which are repeated in time, the optimum renewal rate of females is lowered relative to individual selection on a criterion measured once. Numerical values have been calculated for different species, with given reproduction parameters for each one.

A line of mice, at its limit to selection for high body weight did not decline in performance over 11 generations of random mating, neither did it respond when selection was renewed. The experiment tested a method of improving body weight by a scheme which had earlier increased litter size under similar circumstances. The scheme was to derive partially inbred lines from the plateaued line, to select during inbreeding and, finally, to cross the best inbreds. Body weight was not increased, but the study allowed further examination of the residual genetic variance in the line.

During inbreeding, the inbred lines became clearly differentiated in body weight, proving that loci controlling body weight had not become fixed. There was also a significant response to selection for a lower body weight during inbreeding. The pattern of results suggested the segregation of recessive genes, detrimental to high body weight but which selection had become inefficient at removing. A genetic model compatible with the results accommodated several such recessives, perhaps as many as 10, each with an effect of about two-thirds of a standard deviation (or some equivalent combination of gene number and effect), and at frequencies of around 0·2. Nevertheless, the total improvement in body weight to be gained by their elimination was only half a gram, or less than 2 %. Thus, substantial genetic effects can occur at individual loci despite trivially low heritabilities and negligible potential gains.

Copper concentrations were determined in whole blood, plasma and caeruloplasmin and calculated for red cells and non-caeruloplasmin copper in plasma in 215 female sheep, 9 months old, belonging to the Scottish Blackface, Cheviot and Welsh Mountain breeds of sheep and their crosses. Copper determinations were also made on red cells and plasma, and calculated for whole blood, of a contemporary group of 107 female sheep of the same breeds at the age of 4 years. Further, plasma copper concentrations were determined for these 107 sheep from samples taken on several occasions some years earlier.

Within breed, sheep of type Hb B had significantly higher levels of copper than sheep of type Hb A in whole blood and most of the blood components. The biggest differences were found in plasma and were 19 ng/100 ml for one group and 37 Jig/100 ml for the other. Type Hb AB sheep were intermediate in copper level. The differences in plasma copper level associated with Hb type were present and of similar magnitude at different ages, seasons and average flock levels of copper.

After adjustment for the effects of Hb type, breed differences in copper levels were significant for whole blood and all components but much less pronounced for red cells than for plasma. Copper levels in plasma and red cells were only moderately correlated (r = 0·23–0·40).

Combined evidence suggests the existence of a gene with a marked effect on copper level which is linked to the locus for Hb type.

The concentrations of maternal immunoglobulin in 2-day-old lambs varied widely. They were significantly correlated with the lengths of pregnancy and the serum protein concentrations of the adult female sheep (ewes), but not with the colostrum immunoglobulin concentrations, nor with the weights or ratios of weights of the lambs and ewes. The mean concentrations were as high in Merino as in Blackface lambs.

Although there was some evidence that colostrum production was higher in ewes with twins than in ewes with single lambs, the immunoglobulin concentrations in the lambs fell significantly as litter size increased. They were significantly higher in male than in female twins, and in twins from litters containing both sexes than in twins from litters of one sex, but the difference between single males and females was not significant. Nor was the difference between the first and second born of each pair of twins. Twins and triplets born to ewes aged 7 years or more had particularly low concentrations. No other effects of the age of the ewe were found. The concentrations fell significantly as the date of lambing during the season advanced, and there were significant annual variations which could not be attributed to the weather. The correlation coefficients for the concentrations in lambs born to the same ewe in successive years were 0·309 and 0·298 (P < 0·001), respectively, for Merino and Blackface lambs.

The mean concentration in lambs which died subsequently from infections was significantly lower than in the surviving lambs, but many lambs with very low concentrations survived.

Competition for oat grain between sheep grazing on scant, poor quality pasture was studied in three flocks of sheep. A daily feed of 450 g per head was fed in troughs with the space per sheep varying from 4 to > 50 cm. Records were taken of sheep behaviour during the first 3 min of feeding.

There was no fighting in the competition for feed, but dominance of individuals and of groups of sheep occurred. With abundant trough space, certain sheep led the way to the feed trough and were termed leaders, but ‘leadership’ was a characteristic unrelated to competitiveness during feeding. With restricted trough space most sheep raced to the feed trough at feeding time. The rate of disturbance of the sheep from the feed trough increased with decreased space per sheep, particularly below 12 cm/sheep. As the rate of disturbance increased a progressively greater proportion of sheep stopped competing for feed and became non-feeders. Neither the rate of disturbance of the sheep nor the proportion not feeding was related to body weight, but these were largely individual characteristics of sheep.

In a flock of mixed age Merino wethers, the 1-year-old and 7-yearold sheep were the least competitive, while in a flock of wether sheep of seven different breeds but of similar age, Merinos were least competitive.

From these experiments it is suggested that a minimum trough space of 16 cm be allowed when daily grain supplements are fed to grazing sheep.

In three experiments housed Greyface (Border Leicester × Scottish Blackface) ewes of mean live weight 68 kg received 0·91 kg hay plus 0·91 kg molassed sugar beet pulp daily during the second half of pregnancy and in the first 3 weeks of lactation. Comparisons were made with additions of crude protein given as urea or groundnut cake either during the whole period or only during early lactation. In one experiment, increasing the daily intake of digestible crude protein from 88 to about 140 g had no effect on the weight of the lamb at birth or at 3 weeks. In the other two experiments, in which the increases were from 58·70 g to 131·161 g or from 80 to about 125 g digestible crude protein per day there were highly significant increases in the weight of the lamb at birth (+0·43 and +0·31 kg) and 3 weeks (+1·44 and +1·46 kg). Introduction of either urea or groundnut cake to the diet on the day after lambing significantly increased the the 3-week weights of the lambs by amounts which were comparable to those found when urea had also been given during pregnancy. Supplementation with either urea or groundnut cake did not significantly increase ewe live weight.

Concentrations of urea in the blood of the ewes were highly significantly increased by either urea or groundnut supplementation. There were indications that a concentration below 10 mg/100 ml in the blood of the ewes in late pregnancy or early lactation was associated with a reduction in lamb growth rates.

Twenty-seven North Country Cheviot ewes, each carrying twin foetuses and having a mean body weight at 6 weeks prior to parturition of 81 kg were individually penned and offered a constant daily intake of 16·75 MJ metabolizable energy during the last 6 weeks of gestation. At parturition the ewes were allocated to one of three dried grass/concentrate diets containing (1) 10·3, (2) 13·6 or (3) 16·9 % crude protein (CP) and 10 MJ metabolizable energy (ME) per kg. The mean daily CP intakes for diets 1 to 3 were 273, 340 and 415 g respectively and the mean daily ME intake was 25 MJ. Within each level of dietary CP intake the lambs were weaned at either 25, 35 or 41 days of age.

There were no significant diet × stage of weaning interactions in milk yield or ewe body-weight change during lactation. The mean daily levels of milk production were 2·4, 2·9 and 3·1 kg for diets 1 to 3 respectively. The corresponding values for ewe body-weight loss were 118, 170 and 265 g per day. When the diet contained 13·8% CP the incremental increase in milk production per unit increase in protein intake was 4·2 g/g. This gave an incremental increase in lamb growth rate of 0·79 g/g and was equivalent to the associated incremental increase in ewe body-weight loss.

A reduction in the concentration of CP in the ewes' diet when the lambs are 3 weeks of age may be a useful practical procedure for decreasing milk production and for reducing the body-weight loss of the ewe in a frequent breeding system.

Two trials were conducted using two breeds of sheep varying in prolificacy but producing high commercial milk yields. In the first, 85 Chios ewes were assigned at 10 weeks before lambing to one of three planes of feeding: L, straw ad libitum; M, straw ad libitum + 0·5 kg concentrates; and H, straw ad libitum +1·0 kg concentrates. Six weeks prior to lambing, treatment L was stopped and all 85 ewes were re-randomized to treatments M and H. They were kept on these treatments until 14 days after lambing. In the second trial, 54 Chios and 56 Awassi ewes were allocated to the M and H treatments 6 weeks prior to lambing. After lambing they were fed ad libitum on straw and concentrates for 28 days.

The mean metabolizable energy intake (Meal/day) over the 6-week period before lambing was 2·78 and 3·96 for Chios ewes in Trial 1, 2·39 and 3·51 for Chios ewes in Trial 2 and 2·66 and 3·72 for Awassi ewes in Trial 2, for the M and H treatments respectively.

In both trials the treatment of the ewes affected the birth v/eight of twin and triplet lambs but not that of singles. In Trial 1, the differences in 14-day milk yield between treatments M and H were highly significant. In Trial 2, however, in which the ewes were fed ad libitum during lactation, no differences in the 14-day or the 28-day milk yields were observed for either breed. It is concluded that milk yields in early lactation are closely related to actual plane of nutrition in lactation but may also be affected by the body condition of the ewe at lambing, which may in turn be influenced by a low level of feeding in pregnancy.

1. A total of sixty, 7-day-old British Friesian male calves, reared on a conventional early-weaning system, were used in two experiments in which dried skim milk was partially replaced by levels of 7, 14 and 21 % cooked potato flour (CPF). In the first experiment the diets were iso-energetic but differed in total nitrogen contents, whilst in the second experiment, casein was used to make the diets iso-nitrogenous.

2. In both experiments, diets containing CPF depressed growth rate from 4 to 18 days on treatment (11 to 25 days of age) and reduced the firmness of the faeces. These effects were correlated with the concentrations of CPF in the diets, live-weight gain being depressed by 20%, and the firmness of the faeces by 14%, for each 10 % inclusion of CPF. After 18 days on treatment (25 days of age) these effects became less pronounced.

3. The overall performance of calves to weaning (after 35 days on treatment) was similar on all diets. Daily live-weight gains from 4 to 56 days and 35 to 56 days did not differ between treatments. 4. It was concluded that whilst the inclusion of CPF in the diets of milk-fed calves was unlikely to have any permanent effect on the live weight of calves at 5 or 8 weeks of age its use in milk diets for calves of less than 3 weeks of age must be limited if loose faeces are to be avoided.

1. A split-plot design was used to study apparent digestibility of dry matter, gross energy and nitrogen of a whole grain wheat diet and processed (hammermilled, rolled or hammermilled and then steam-pelleted) wheat diets by eight small (33·9 ± 0·1 kg) and eight large (70±1·7 kg) pigs. Metabolizable energy and nitrogen retention were also studied with the small pigs.

2. The processed wheat diets were superior to the whole grain wheat diet in all the parameters measured.

3. There were no significant differences between the performance of pigs given the differently processed wheat diets.

4. Apparent digestibility of dietary components particularly in the whole wheat diet was significantly higher when diets were given to small pigs than when given to large pigs.

Female pigs of the Pietrain and Large White breeds, 18 from each, selected to form a logarithmic weight range, were dissected into their major carcass tissues. Relative to carcass growth, fat was the fastest developing tissue in both breeds; fat and muscle grew at a rate higher, and bone at a rate lower, than the carcass. The growth of bone relative to carcass growth was faster in the Large White; differences between breeds in the growth of muscle and fat were not significant. Muscle weights and muscle: bone ratios, estimated at the same empty body weight, were greater for the Pietrain over the entire body weight range studied. There was no significant difference in muscle: bone ratio between the Large Whites used in the present study and those dissected by McMeekan over 30 years previously. The breed difference in the proportion of muscle and bone at the same body weight is attributed to a greater maturity of the Pietrain.

Half carcasses of 18 Pietrain and 18 Large White female pigs were each dissected into 93 muscle units. An allometric analysis of the weight of these units relative to total muscle revealed increasing craniocaudal and distoproximal growth gradients, which were more pronounced in the Pietrain.

The greater total weight of muscle, shown previously for the Pietrain at any given body weight over the range studied, was not due to higher muscle weights in any particular region at birth, but at 60 kg body weight was due to heavier high impetus muscles. Heart weight relative to total muscle weight was higher for the Large White over the entire range.

It is concluded that for the animals studied the changes in muscle distribution are related to the functional demands of an increase in body size, and that the muscle distribution of pigs can differ between breeds.

The appetite and growth of individually-fed, weaned Hampshire and Saddleback piglets and of Hampshire and Large White × Landrace piglets were compared in three experiments from 14 to 49, 28 to 55 and 21 to 45 days of age. There was a reduced rate of growth in the Hampshire piglets, which was not found to be related to any need of Hampshire piglets for a higher quality diet. Neither was there any reduction in the efficiency with which Hampshire piglets used ingested nutrients, nor a differential rate of deposition of any body component. Hampshire piglets ate less food than Saddleback or Large White × Landrace piglets and this reduced appetite was largely accounted for by the lower body size.

The recording of total lactation yield for individual cows can be timeconsuming and costly. Periodic sampling at intervals throughout lactation offers an acceptable alternative, and a single day's production can be made to furnish a useful guide, by using an equation relating total to daily production.

Errors of estimation are affected by the degree of consistency of daily production, parity and individual herd management, so that estimates could be biased and have a standard error of nearly 20% if these effects are disregarded. Coefficients in the prediction equation must therefore be developed for individual herds.