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Oestrus in relation to peak oestradiol levels in ovariectomized Galloway cows

Published online by Cambridge University Press:  18 August 2016

A. O. Darwash ,
G. E. Lamming  and
L. M. Hicking
A. O. Darwash
Affiliation:
Cattle Fertility Research Group, School of Biological Sciences, University of Nottingham, Sutton Bonington Campus, Loughborough LE12 5RD, UK
G. E. Lamming
Affiliation:
Cattle Fertility Research Group, School of Biological Sciences, University of Nottingham, Sutton Bonington Campus, Loughborough LE12 5RD, UK
L. M. Hicking
Affiliation:
Cattle Fertility Research Group, School of Biological Sciences, University of Nottingham, Sutton Bonington Campus, Loughborough LE12 5RD, UK
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Abstract

The objective of the present study was to characterize the variation in oestrous behaviour among ovariectomized cows in response to a measured dose of oestradiol benzoate (OB) . In study 1, nine ovariectomized Galloway cows, approximately 10 years old, were challenged with an intramuscular injection of either 0·25, 0·5 or 1·0 mg of OB. Following this, 0·5 mg OB was chosen as the appropriate dose required to induce oestrous behaviour in ovariectomized Galloway cows. In study 2, nine cows injected with 0·5 mg OB were monitored for oestrous behaviour using KAMAR® heat mount detectors. Blood samples for plasma oestradiol-17β (E2) assay were taken every 4 h between 0 to 72 h and once at 96 h, following OB administration. The plasma E2 concentrations between 0 to 96 h following OB administration differed significantly ( P < 0·001) among cows. The interval to peak E2 concentrations averaged 17·42 (s.e. 2·21) h and the mean peak E2 concentration was 5·86 (s.e. 0·57) ng/l. The mean interval from OB administration until onset of mounting activity was 24·57 (s.e.2·38) h and the duration of oestrus averaged 10·5 (s.e. 1·99) h . In all cows, mounting activity occurred following peak E2 concentrations after an average interval of 7·73 (s.e. 1·84) h. There was no significant association between peak E2 concentrations and the interval to onset of mounting activity or its duration. Since the variation among Galloway cows in the manifestation of behavioural oestrus was independent of systemic E2 concentrations, it implies that there are inherent differences between individuals in the sensitivity of the hypothalamus to physiological E2 thresholds. This may help to explain the incidence of silent ovulation in some animals and the occurrence of overt oestrus associated with follicular activity during the luteal phase of the cycle or during the various stages of pregnancy, in the presence of high plasma progesterone concentrations.

Keywords

cowsoestrusoestradiolovariectomized females.
Type
Reproduction
Information
Animal Science , Volume 72 , Issue 2 , April 2001 , pp. 401 - 405
Copyright
Copyright © British Society of Animal Science 2001

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References

Allrich, R. D. 1994. Symposium: estrus, new devices and monitoring. Endocrine and neural control of estrus in dairy cows. Journal of Dairy Science 77: 2738–2744.CrossRefGoogle Scholar
Asdell, S. A., De Alba, J. and Roberts, S. J. 1945. The levels of ovarian hormones required to induce heat and other reactions in the ovariectomized cows. Journal of Animal Science 4: 277–284.CrossRefGoogle Scholar
Barr, H. L. 1975. Influence of estrous detection on days open in dairy herds. Journal of Dairy Science 58: 246–247.CrossRefGoogle ScholarPubMed
Bosworth, R. W., Ward, G., Call, E. P. and Bonewitz, E. R. 1972. Analysis of factors affecting calving intervals of dairy cows. Journal of Dairy Science 55: 334–338.CrossRefGoogle Scholar
Britt, J. H., Scott, R. G., Armstrong, J. D. and Whitcare, M. D. 1986. Determinants of estrus behavior in lactating Holstein cows. Journal of Dairy Science 69: 2195–2202.CrossRefGoogle ScholarPubMed
Carrick, M. J. and Shelton, J. N. 1969. Oestrogen-progesterone relationships in the induction of oestrus in spayed heifers. Journal of Endocrinology 45: 99–109.CrossRefGoogle ScholarPubMed
Chenault, J. R., Thatcher, W. W., Karla, P. S., Abrams, R. M. and Wilcox, C. J. 1975. Transitory changes in plasma progestins, estradiol and luteinizing hormone approaching ovulation in the bovine. Journal of Dairy Science 58: 709–717.CrossRefGoogle ScholarPubMed
Darwash, A. O., Lamming, G. E. and Woolliams, J. A. 1999. The potential for identifying heritable endocrine parameters associated with fertility in post-partum dairy cows. Animal Science 68: 333–347.CrossRefGoogle Scholar
Davidge, S. T., Wiebold, J. L., Senger, P. L. and Hilers, J. K. 1987. Influence of varying levels of blood progesterone upon estrous behavior in cattle. Journal of Animal Science 64: 126–132.CrossRefGoogle ScholarPubMed
Dijkhuizen, T. J. and van Erdenburg, F. C. M. 1997. Behavioural signs of oestrus during pregnancy in lactating dairy cows. Veterinary Quarterly 19: 194–196.CrossRefGoogle ScholarPubMed
Erb, R. E. and Morrison, R. A. 1958. Estrus after conception in a herd of Holstein-Friesian cattle. Journal of Dairy Science 41: 267–274.CrossRefGoogle Scholar
Glencross, R. G., Munro, I. B., Senior, B. E. and Pope, G. S. 1973. Concentrations of oestradiol in jugular venous plasma of cows during the oestrous cycle and in early pregnancy. Acta Endocrinologica 73: 374–384.Google ScholarPubMed
Hansel, W. and Convey, E. 1983. Physiology of the oestrous cycle. Journal of Animal Science 57: (suppl. 2) 404–424.Google Scholar
King, G. J., Hernik, J. F. and Robertson, H. A. 1976. Ovarian function and estrus in dairy cows during early lactation. Journal of Animal Science 42: 688.CrossRefGoogle ScholarPubMed
Lamming, G. E. and Darwash, A. O. 1998. The use of milk progesterone profiles to characterize components of subfertility in milked cows. Animal Reproduction Science 52: 175–190.CrossRefGoogle Scholar
MacMillan, K. L., Lean, I. J. and Westwood, C. T. 1996. The effects of lactation on the fertility of dairy cows. Australian Veterinary Journal 73: 141–147.CrossRefGoogle Scholar
Mann, G. E., Lamming, G. E. and Fry, M. D. 1995. Plasma oestradiol and progesterone during early pregnancy in the cow and the effects of treatment with buserlin. Animal Reproduction Science 37: 121–131.CrossRefGoogle Scholar
Murphee, R. L. and Tsou, R. C. 1975. Blood hormones in ovariectomized heifers. Journal of Animal Science 40: 189 (abstr. ).Google Scholar
Roy, G. P., Singh, A. P., Akhtar, M. H., Prasad, K. M., Singh, R. B. and Sinha, S. N. 1990. Incidence of mid-cycle oestrus in cattle and buffaloes. Indian Journal of Animal Reproduction 11: 158.Google Scholar
Senger, P. L. 1994. The estrus detection problem: new concepts, technologies and possibilities. Journal of Dairy Science 77: 2745–2753.CrossRefGoogle ScholarPubMed
Stevenson, J. S. and Britt, J. H. 1977. Detection of estrus by three methods. Journal of Dairy Science 60: 1994–1998.CrossRefGoogle ScholarPubMed
Stevenson, J. S., Lamb, G. C., Kobayashi, Y. and Hoffman, D. P. 1998. Luteolysis during two stages of the estrous cycle: subsequent endocrine profile associated with radiotelemetrically detected oestrus in heifers. Journal of Dairy Science 81: 2897–2903.CrossRefGoogle ScholarPubMed
Thomas, I. and Dobson, H. 1989. Oestrus during pregnancy in the cow. Veterinary Record 124: 387.CrossRefGoogle ScholarPubMed
Vailes, L. D., Wasburn, S. P. and Britt, J. H. 1992. Effects of various steroid mileus or physiological states on sexual behaviour of Holstein cows. Journal of Animal Science 70: 2094–2103.CrossRefGoogle ScholarPubMed