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Haemoglobin N of sheep. Age, breed and seasonal distribution

Published online by Cambridge University Press:  02 September 2010

G. Efremov
Affiliation:
Department of Medicine, The Veterinary College of Norway, oslo, Norway
M. Brænd
Affiliation:
Department of Medicine, The Veterinary College of Norway, oslo, Norway
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Extract

The occurrence of Hb N in sheep has been investigated by means of starch gel electrophoresis.

In lambs, Hb N occurred in higher relative amounts than in adults, but not until 9 days of age. One-month-old lambs often showed an Hb N content as high as 10–30%.

Haemoglobin N was observed most in sheep of phenotype AA, less in those of type AB and was found to be absent in BB animals. It was also provoked experimentally by bleedings in sheep of types AA and AB but not in those of type BB.

Comparisons between breeds showed differences in the expression of Hb N. It occurred most regularly in Old Norwegian sheep (Spæl), but usually in concentrations of less than 1%. Hb N was, however, also found in other Norwegian breeds, in Cheviots and in Spanish sheep but not in sheep of the Oxford Down breed.

In two flocks of Spæl and Dala sheep where frequent bleedings were made, Hb N was observed at all times of the year.

Type
Research Article
Copyright
Copyright © British Society of Animal Science 1966

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References

REFERENCES

Baglioni, C. 1963. Correlations between genetics and chemistry of human hemoglobins. Molecular Biology (Acad. Press), 4: 4405.Google Scholar
Blunt, M. H., & Evans, J. V., 1963. Changes in the concentration of potassium in the erythrocytes and in hæmoglobin type in Merino sheep under a severe anaemic stress. Nature, Land., 200: 1215.CrossRefGoogle Scholar
Bræend, M., & Efremov, G., 1965a. Haemoglobin N of sheep. Nature, Land., 205: 205–186.CrossRefGoogle Scholar
Bræend, M., & Efremov, G., 1965b. Haemoglobins, haptoglobins and albumins of horses. Proc. 9th Europ. Anim. Blood Group Conf.: pp. 253259.CrossRefGoogle Scholar
Bræend, M., Efremov, G., & Helle, O., 1964. Abnormal haemoglobin in sheep. Nature, Land., 204: 700.CrossRefGoogle Scholar
Drabktn, D. L., 1946. Spectrophotometric studies. XIV. The crystallographic and optical properties of the hemoglobin of man in comparison with those of other species. J. biol. Chem., 164: 703.Google Scholar
Efremov, G., 1963. Doctoral Thesis. University of Belgrade.Google Scholar
Efremov, G., & Bræend, M., 1965. Haemoglobins, transferrins and albumins of sheep and goats. Proc. 9th Europ. Anim. Blood. Group Conf.: pp. 313320.Google Scholar
Gahne, B., 1961. Studies of transferrins in serum and milk from Swedish cattle. Anim. Prod., 3: 3135.Google Scholar
Huisman, T. H. J., Van Vliet, G., & Sebens, T., 1958. Sheep haemoglobins. Nature, Lond., 182: 182–181.Google Scholar
Jacob, F., & Monod, J., 1961. Genetic regulatory mechanisms in the synthesis of proteins. J. molec. Biol., 3: 3318.CrossRefGoogle ScholarPubMed
Muller, C. J., 1961. Molecular Evolution. 90 pp. Van Gorcum. Assen, The Netherlands.Google Scholar
Shreffler, D. C., & Vinograd, J., 1962. Molecular hybridization between sheephemoglobin variants. Biochim. biophys. Ada., 65: 65101.CrossRefGoogle ScholarPubMed
Ullrey, D. E., Miller, E. R., Long, C. H., & Vincent, B. H., 1965. Sheep hematology from birth to maturity. I. Erythrocyte population, size and hemoglobin concentration. J. Anim. Sci., 24: 24135.Google ScholarPubMed
Van Der Helm, H. J., Van Vliet, G., & Huisman, T. H. J., 1957. Investigations on two different hemoglobins of the sheep. Archs. Biochem. Biophys., 72: 72331.CrossRefGoogle ScholarPubMed
Van Vliet, G., & Huisman, T. H. J., 1964. Changes in the haemoglobin types of sheep as a response to anaemia. Biochem. J., 93: 401409.Google Scholar