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Genetic resistance to gastro-intestinal nematode parasites in Red Maasai, Dorper and Red Maasai X Dorper ewes in the sub-humid tropics

Published online by Cambridge University Press:  18 August 2016

R.L. Baker
Affiliation:
International Livestock Research Institute (ILRI), PO Box 30709, Nairobi, Kenya
D.M. Mwamachi
Affiliation:
Kenya Agricultural Research Institute (KARI), PO Box 16, Mtwapa, Kenya
J.O. Audho
Affiliation:
International Livestock Research Institute (ILRI), PO Box 30709, Nairobi, Kenya
E.O. Aduda
Affiliation:
International Livestock Research Institute (ILRI), PO Box 30709, Nairobi, Kenya
W. Thorpe
Affiliation:
International Livestock Research Institute (ILRI), PO Box 30709, Nairobi, Kenya
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Abstract

Resistance to naturally acquired gastro-intestinal (GI) nematode parasite infections (predominantly Haemonchus contortus) was studied in 166 Red Maasai, 230 Dorper and 294 crossbred (Red Maasai Х Dorper) ewes in the sub-humid coastal region of Kenya. Live weights (LWT), blood packed-cell volume (PCV) and faecal egg counts (PEC) were recorded at mating, 3 months post mating, 1 week before lambing and 1, 2 and 3 months post lambing for four separate lambings that took place between 1993 and 1996. The Red Maasai ewes were more resistant to GI nematode infections than Dorper ewes as shown by their significantly lower FEC and significantly higher PCV at most of the sampling times over the reproductive cycle. The breed difference for FEC was significant in the lactating ewes but not in the non-lactating ewes. At most sampling times, the crossbred ewes were as susceptible as the Dorper ewes in terms of both PCV and FEC, particularly at the 1 and 2 month post-lambing samplings. Resistance was also manifested by a lower proportion of ewes having to be treated with an anthelmintic and a lower mortality rate in the Red Maasai than the Dorper. The Red Maasai ewes were significantly lighter by about 1 to 2 kg than the Dorper ewes at all sampling times. There was a significant increase in FEC and decrease in PCV over the first 2 months of lactation in lactating ewes compared with non-lactating ewes. This peri-parturient increase in FEC occurred in both breeds and the crossbreds but was more marked in the susceptible Dorper ewes.

Type
Research Article
Copyright
Copyright © British Society of Animal Science 1999

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References

Baker, R.L. 1998. A review of genetic resistance to gastrointestinal nematode parasites in sheep and goats in the tropics and evidence for resistance in some sheep and goat breeds in sub-humid coastal Kenya. Animal Genetic Resources Information Bulletin 24: 1330.Google Scholar
Baker, R.L., Mwamachi, D.M., Audho, J.O., Aduda, E.O. and Thorpe, W. 1998a. Resistance of Galla and Small East African goats in the sub-humid tropics to gastrointestinal nematode infections and the peri-parturient rise in faecal egg counts. Veterinary Parasitology 79: 5364.CrossRefGoogle ScholarPubMed
Baker, R.L., Mwamachi, D.M., Audho, J.O. and Thorpe, W. 1994. Genetic resistance to gastrointestinal nematode parasites in Red Maasai sheep in Kenya. Proceedings of the fifth world congress on genetics applied to livestock production, Guelph, vol. 20, pp. 277280.Google Scholar
Baker, R.L., Rege, J.E.O., Tembely, S., Mukasa-Mugerwa, E., Anindo, D., Mwamachi, D.M., Thorpe, W. and Lahlou-Kassi, A. 1998b. Genetic resistance to gastrointestinal nematode parasites in some indigenous breeds of sheep and goats in East Africa. Proceedings of the sixth world congress on genetics applied to livestock production, Armidale, vol. 25, pp. 269272.Google Scholar
Barger, I.A. 1993. Influence of sex and reproduction status on susceptibility of ruminants to nematode parasitism. International journal for Parasitology 23: 463469.CrossRefGoogle ScholarPubMed
Bishop, S.C. and Stear, M.J. 1997. Modelling responses to selection for resistance to gastro-intestinal parasites in sheep. Animal Science 64: 469478.Google Scholar
Bullerdiek, P. 1996. Appraisal of various management interventions in a sheep production system with high gastrointestinal parasite challenge in a subhumid tropical environment. Ph.D. thesis, Humboldt University, Berlin, Germany.Google Scholar
Courtney, C.H., Parker, C.F., McClure, K.E. and Herd, R.P. 1984. A comparison of the periparturient rise in faecal egg counts of exotic and domestic ewes. International Journal for Parasitology 14: 377381.Google Scholar
Doligalska, M., Moskwa, B. and Niznikowski, R. 1997. The repeatability of faecal egg counts in Polish Wrzoswka sheep. Veterinary Parasitology 70: 241246.CrossRefGoogle ScholarPubMed
Donald, A.D., Morley, F.W.H., Waller, P.J., Axelson, A., Dobson, R.J. and Donnelly, J. 1982. Effects of reproduction, genotype and anthelmintic treatment of ewes on Ostertagia spp. populations. International Journal for Parasitology 12: 403411.Google Scholar
Gruner, L., Bouix, J., Cabaret, J., Boulard, C, Cornet, J., Sauve, C, Molenat, G. and Calamel, M. 1992. Effect of genetic type, lactation and management on helminth infections of ewes in an intensive grazing system on irrigated pasture. International Journal for Parasitology 22: 919925.Google Scholar
Hansen, J. and Perry, B. 1994. The epidemiology, diagnosis and control of helminth parasites of ruminants, second edition. International Laboratory for Research on Animal Diseases (ILRAD), Nairobi, Kenya.Google Scholar
Harvey, W.R. 1990. Users guide for the PC-2 version of the LSMLMW and MIXMDL mixed model least squares and maximum likelihood computer program. Ohio State University, Columbus, Ohio.Google Scholar
Inyangala, B.A.O., Rege, J.E.O. and Itulya, S. 1992. The performance of Dorper and Dorper Х Red Maasai sheep. Discovery and Innovation 4: 7682.Google Scholar
Jaetzold, R. and Schmidt, H. 1983. Farm management handbook of Kenya. Natural conditions and farm information — part C, East Kenya (eastern and coast provinces), vol. 2. Ministry of Agriculture in cooperation with the German agricultural team of the Germany Agency for Technical Cooperation (GTZ).Google Scholar
Kiriro, P.M. 1994. Estimate of genetic and phenotypic parameters for the Dorper, Red Maasai and their crosses. In Second biennial conference of the African small ruminant research network (ed. Lebbie, S.H.B., Rey, B. and Irungu, E.K.), pp. 229234. International Livestock Centre for Africa, Addis Ababa, Ethiopia.Google Scholar
Ministry of Agriculture, Fisheries and Food. 1977. Manual of veterinary parasitology laboratory technique. Ministry of Agriculture, Fisheries and Food technical bulletin, no. 18. Her Majesty’s Stationery Office, London.Google Scholar
Morris, C.A., Bisset, S.A., Vlassoff, A., West, C.J. and Wheeler, M. 1998. Faecal nematode egg counts in lactating ewes from Romney flocks selectively bred for divergence in lamb faecal egg count. Animal Science 67: 283288.Google Scholar
Morris, C.A., Watson, T.G., Baker, R.L., Hurford, A.P. and Hosking, B.C. 1993. Repeatability estimates and selection flock effects for faecal nematode egg counts in Romney breeding ewes. Proceedings of the New Zealand Society of Animal Production 53: 227229.Google Scholar
Mugambi, J.M., Bain, R.K., Wanyangu, S.W., Ihiga, M. A., Duncan, J.L., Murray, M. and Stear, M.J. 1997. Resistance of four sheep breeds to natural and subsequent artificial Haemonchus contortus infection. Veterinary Parasitology 69: 265273.CrossRefGoogle ScholarPubMed
Mugambi, J.M., Wanyangu, S.W., Bain, R.K., Owango, M.O., Duncan, J.L. and Stear, M.J. 1996. Response of Dorper and Red Maasai lambs to trickle Haemonchus contortus infections. Research in Veterinary Science 61: 218221.Google Scholar
Paris, J., Murray, M. and McOdimba, F.A. 1982. An evaluation of the sensitivity of current parasitological techniques for the diagnosis of bovine African trypanosomiasis. Acta Tropica 39: 307316.Google Scholar
Payne, R.W., Lane, P.W., Digby, P.G.N., Harding, S.A., Leech, P.K., Morgan, G.W., Todd, A., Thompson, R., Tunncliffe Wilson, G., Welham, S.J. and White, R.P. 1997. Genstat 5 release 3 reference manual. Clarendon Press, Oxford.Google Scholar
Preston, J.M. and Allonby, E.W. 1978. The influence of breed on the susceptibility of sheep and goats to a single experimental infection with Haemonchus contortus. Veterinary Record 103: 509512.CrossRefGoogle ScholarPubMed
Preston, J.M. and Allonby, E.W. 1979. The influence of breed on the susceptibility of sheep to Haemonchus contortus infection in Kenya. Research in Veterinary Science 26: 134139.Google Scholar
Romjali, E., Dorny, P., Batubara, A., Pandey, V.S. and Gatenby, R.M. 1997. Peri-parturient rise in faecal strongyle egg counts of different genotypes of sheep in North Sumatra, Indonesia. Veterinary Parasitology 68: 191196.Google Scholar
Statistical Analysis Systems Institute. 1989. SAS/STAT user’s guide, version 6, fourth edition, volume 1. Cary, NC.Google Scholar
Tembely, S., Lahlou-Kassi, A., Rege, J.E.O., Mukasa-Mugerwa, E., Anindo, A., Sovani, S. and Baker, R.L. 1998. Breed and season effects on the peri-parturient rise in nematode egg output in indigenous ewes in a cool tropical environment. Veterinary Parasitology 77: 123132.Google Scholar
Wanyangu, S.W., Mugambi, J.M., Bain, R.K., Duncan, J.L., Murray, M. and Stear, M.J. 1997. Response to artificial and subsequent natural infection with Haemonchus contortus in Red Maasai and Dorper ewes. Veterinary Parasitology 69: 275282.Google Scholar
Woolaston, R.R. 1992. Selection of Merino sheep for increased and decreased resistance to Haemonchus contortus: peri-parturient effects on faecal egg counts. International Journal for Parasitology 22: 947953.Google Scholar
Zajac, A.M., Herd, R.P. and McClure, K.E. 1988. Trichostrongylid parasite population in pregnant or lactating and unmated Florida Native and Dorset Rambouillet ewes. International Journal for Parasitology 18: 981985.CrossRefGoogle ScholarPubMed