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Effect of the β-adrenergic agonist cimaterol and dietary protein level on fat young sheep given diets containing submaintenance levels of dietary energy

Published online by Cambridge University Press:  02 September 2010

H. Galbraith ,
B. Minassie  and
J. R. Scaife
H. Galbraith
Affiliation:
Department of Agriculture, University of Aberdeen, 581 King Street, Aberdeen AB24 5UA
B. Minassie
Affiliation:
Department of Agriculture, University of Aberdeen, 581 King Street, Aberdeen AB24 5UA
J. R. Scaife
Affiliation:
Department of Agriculture, University of Aberdeen, 581 King Street, Aberdeen AB24 5UA
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Abstract

Thirty Suffolk cross wether sheep aged about 12 months and weighing 57 kg on average were used. They had been given previously a high energy diet to produce a fat body condition and average condition score of 3·7. Animals were allocated to an initial slaughter group (IS) or to four dietary treatment groups (UL, UH, CL and CH) based on sugar-beet feed (L) or white-fish meal (H) supplemented with chopped straw and pelleted, without (UL and UH) or with (CL and CH) the β-adrenergic agonist cimaterol, to provide an estimated 20 g (L) or 130 g (H) rumen undegradable protein per kg dry matter (DM). The sheep were offered 0·3 kg of the appropriate pelleted diet in addition to 200 to 400 g of chopped barley straw to provide proportionately 0·7 of the estimated metabolizable energy requirement for maintenance and, where appropriate, 2·5 mg cimaterol per day. Comparisons were made for the main effects of dietary protein intake and cimaterol and interactions between dietary protein and cimaterol.

The animals on dietary treatments were slaughtered after 49 days. The animals exhibited variable reductions in live weight and weights of carcass and non-carcass components in comparison with the IS group and in response to restricted dietary energy intake. The only effect due to the elevated dietary protein provision was a smaller loss in live weight compared with the low protein diet. In contrast, compared with responses recorded in its absence, treatment with cimaterol resulted in significantly greater values for weights of cold carcass, cross-sectional area o/m. longissimus dorsi and weights of DM, crude protein and ash in the carcass with significantly smaller weights for raw fleece. In comparison with the IS group, significantly smaller changes due to cimaterol were recorded for the weights of carcass crude protein and ash. Cimaterol treatment significantly increased the weight loss of fat in the carcass and in the perirenal and retroperitoneal, but not omental, depots as components of fleece-free non-carcass fat which was also significantly reduced in total. Interactions suggested that losses in carcass weight and DM in the presence of cimaterol were less and gains in carcass protein and ash greater, on the high than on the low protein diet. The results suggest that under conditions of energy undernutrition cimaterol may induce smaller losses or larger gains in carcass but not non-carcass, crude protein at the expense of fat depletion in carcass and non-carcass fat depots.

Keywords

β-adrenergic agonistcimaterolfat mobilizationsheepunder-nutrition
Type
Research Article
Information
Animal Science , Volume 64 , Issue 2 , April 1997 , pp. 271 - 278
Copyright
Copyright © British Society of Animal Science 1997

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References

Agricultural Research Council. 1980. The nutrient requirements of ruminant livestock. Commonwealth Agricultural Bureaux, Slough, UK.Google Scholar
Beermann, D.Hv Hogue, D. E., Fishell, V. K., Dalrymple, R. H. and Ricks, C. A. 1986. Effects of cimaterol and fishmeal on performance, carcass characteristics and skeletal muscle growth in lambs. Journal of Animal Science 62: 370–380.Google Scholar
Coelho, J. F. S., Galbraith, H. and Topps, J. H. 1981. The effect of a combination of trenbolone acetate and oestradiol- 17β on growth performance and blood, carcass and body characteristics of wether lambs. Animal Production 32: 261–266.Google Scholar
Fattet, I., Hovell, F. D. De B., Ørskov, E. R.Kyle, D. J., Pennie, K. and Smart, R. I. 1984. Undernutrition in sheep. The effect of supplementation with protein on protein accretion. British Journal of Nutrition 52: 561–574.Google Scholar
Galbraith, H., Hatendi, P. R., Alderson, E. M. and Scaife, J. R. 1990. The effect of cimaterol and oestradiol-17β alone or combined on growth and body composition of wether lambs. Animal Production 51: 311–319.Google Scholar
Galbraith, H., McCulloch, T., Scaife, J. R. and Keeling, B. J. 1988. Effect of barley, sugar-beet pulp and protein level in the diet on growth, body composition and blood metabolites and insulin concentration of entire male lambs. Animal Production 46: 514 (abstr.).Google Scholar
Lawes Agricultural Trust. 1977. Genstat V, mark 4.01. Rothamsted Experimental Station, Harpenden, UK.Google Scholar
McNeel, R. L. and Mersmann, H. J. 1995. β-adrenergic receptor subtype transcripts in porcine adipose tissue. Journal of Animal Science 73:1962–1971.CrossRefGoogle ScholarPubMed
MacRae, J. C., Skene, P. A., Connell, A., Buchan, V. and Lobley, G. E. 1988. The action of the β-agonist clenbuterol on protein and energy metabolism in fattening wether lambs. British Journal of Nutrition 59: 457–465.Google Scholar
MacVinish, L. J. and Galbraith, H. 1988. The effect of implantation of trenbolone acetate and oestradiol-17β in wether lambs at two initial live weights on concentrations of steroidal residues and blood glucose, urea and thyroid hormones. Animal Production 47: 75–85.Google Scholar
Maloney, A., Allen, P., Joseph, R. and Tarrant, V. 1991. Influence of beta-adrenergic agonists and similar compounds on growth. In Growth regulation in farm animals (ed. Pearson, A. M. and Dutson, T. R.), pp. 455–574. Elsevier Applied Science, London.Google Scholar
Morand-Fehr, P. and Galbraith, H. 1992. Nutritional characteristics and feeding strategies for fibre-producing goats. In Neiv developments in goat husbandry for quality fibre production (ed. Galbraith, H.), pp. 40–66. University of Aberdeen Studies Committee, Aberdeen.Google Scholar
Nash, J. E., Rocha, H. J. G., Buchan, V., Calder, G. A., Milne, E., Quirke, J. F. and Lobley, G. E. 1994. The effect of acute and chronic administration of the β-agonist cimaterol on protein synthesis in ovine skin and muscle. British journal of Nutrition 71: 501–513.Google Scholar
Newbold, J. R., Garnsworthy, P. C., Buttery, P. J., Cole, D. J. A. and Haresign, W. 1988. Responses of British Friesian steers with or without implants of oestradiol-17β to undegradable dietary protein. Animal Production 46: 181–193.Google Scholar
Rouzbehan, Y., Galbraith, H., Rooke, J. A. and Perrott, J. G. 1994. A note on the effects of dietary inclusion of a yeast culture on growth and ruminal metabolism of lambs given diets containing unground pelleted molassed dried sugar-beet pulp and barley in various proportions. Animal Production 59:147–150.Google Scholar
Russel, A. J. R., Doney, J. M. and Gunn, R. G. 1969. Subjective assessment of body fat in live sheep. Journal of Agricultural Science, Cambridge 72: 451–454.Google Scholar
Shahjalal, Md., Galbraith, H. and Topps, J. H. 1992. The effect of changes in dietary protein and energy on growth, body composition and mohair fibre characteristics of British Angora goats. Animal Production 54: 405–412.Google Scholar
Sinclair, L. A., Galbraith, H. and Scaife, J. R. 1991. Effect of dietary protein concentration and cimaterol on growth and body composition of entire male lambs. Animal Feed Science and Technology 34: 181–192.CrossRefGoogle Scholar
Vipond, J. E., King, M. E., Ørskov, E. R. and Weatherill, G. Z. 1989. Effects of fishmeal supplementation on performance of overfat lambs fed on barley straw to reduce carcass fatness. Animal Production 48: 131–138.Google Scholar