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The effect of diethylstilboestrol, hexoestrol and testosterone on the growth rate and carcass quality of fattening beef steers

Published online by Cambridge University Press:  01 March 1960

T. D. Burgess  and
G. E. Lamming
T. D. Burgess
Affiliation:
University of Nottingham School of Agriculture, Sutton Bonington
G. E. Lamming
Affiliation:
University of Nottingham School of Agriculture, Sutton Bonington
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Extract

The use of the hormones, diethylstilboestrol, hexoestrol and testosterone propionate, as growth stimulants in beef cattle has been studied.

The subcutaneous implantation of 60 mg. stilboestrol into steers fattening in yards produced a highly significant increase in rate of gain (65%) and little difference in the yield and quality of the carcass. The implantation of 24 nig. or 36 mg. of diethylstilboestrol or 30 mg. hexoestrol into Friesian bullocks fattening on pasture produced highly significant increases in rates of gain (29%, 48% and 33% respectively). No significant difference was found in the rates of gain produced by these three treatments.

The oral administration of 10 mg. diethylstilboestrol per head per day for 168 days or the oral administration of 20 mg. rising to 40 mg. testosterone propionate per head per day for 154 days to dizygotic twin steers on equal feed intake significantly increased rate of gain by 15% and 21% respectively Feed efficiency as measured by the pounds of feed required to produce a pound of gain was significantly improved by both treatments. Carcass yield and carcass quality were not significantly affected by either treatment. No significant differences were found between the two treatments.

Examination of the thyroid and adrenal glands of treated and untreated steers revealed no consistent changes in size due to treatment. The gonadotrophin and thyrotrophin content of the anterior pituitary glands of treated and untreated cattle were compared using the male chick bioassay. The results showed that a lower gonadotrophin content was not a factor associated with the extra growth due to treatment, but in two out of three experiments there was some evidence that sex-hormone treatment leads to a mild hyper-thyroidism which, in turn, resulted in a decrease in the thyrotrophin content of the anterior pituitary gland. It was concluded that hyperactivity of the thyroid gland was probably more important in accounting for the extra growth than hyperactivity of the adrenal cortex.

Type
Research Article
Information
Animal Production , Volume 2 , Issue 1 , March 1960 , pp. 93 - 103
Copyright
Copyright © British Society of Animal Science 1960

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References

REFERENCES

Aitken, J. N., & Crichton, J. A., 1956. The effect of hexoestrol implantation on growth and certain carcass characteristics of fattening steers. Brit. J. Nutr., 10: 220.CrossRefGoogle ScholarPubMed
Andrews, F. N., Beeson, W. M., & Johnson, F. D., 1950. The effect of hormones on the growth and fattening of yearling steers. J. Anim. Sci., 9: 677 (Soc. Proa).Google Scholar
Andrews, F. N., Stob, M., Perry, T. W., & Beeson, W. M., 1956. The oral administration of diethylstilbestrol, dienestrol and hexestrol for fattening calves. J. Anim. Sci., 15: 685.Google Scholar
Burgess, T. D., 1956. The effect of hormones on the growth rate and carcass quality of beef cattle and lambs. Unpublished. Thesis, University of Nottingham Library.Google Scholar
Burgess, T. D., & Lamming, G. E., 1957. The use of hormones in animal nutrition. N.A.A.S. quart. Rev., No. 35.Google Scholar
Burgess, T. D., & Lamming, G. E., 1960. The effect of hormones on growth rate and carcass quality of fattening lambs and hoggets. Anim. Prod., 2: 83.Google Scholar
Burris, M. J., Bogart, R., Oliver, A. W., & Mackay, O. A., 1952. The effect of testosterone propionate on the rate of gain, feed efficiency and carcass quality of beef heifers and steers. J. Anim. Sci., 11: 789 (Soc. Proc).Google Scholar
Burris, M. J., Bogart, R., & Oliver, A. W., 1953. Alteration of daily gain, feed efficiency and carcass characteristics in beef cattle with, male hormones. J. Anim. Sci., 12: 740.Google Scholar
Burroughs, W., Culbertson, C. C., Kastelic, J., Cheng, E., & Hale, W. H., 1954. The effects of trace amounts of diethylstilbestrol in rations of fattening steers. Science, 120: 66.Google Scholar
Burroughs, W., Culbertson, C. C., Cheng, E., Hale, W. H., & Homeyer, P., 1955. The influence of oral administration of diethylstilbestrol to beef cattle. J. Anim. Sci., 14: 1015.CrossRefGoogle Scholar
Cahill, V. R., Kunkle, L. E., Klosterman, E. W., Deatherage, F. E., & Wierbicki, E., 1956. Effect of diethylstilbestrol implantation on carcass composition and the weight of certain endocrine glands of steers and bulls. J. Anim. Sci., 15: 701.Google Scholar
Clegg, M. T., & Cole, H. H., 1954. The action of stilbestrol on the growth response in ruminants. J. Anim. Sci., 13: 108.CrossRefGoogle Scholar
Hammond, J., 1955. Progress in Physiology of Farm Animals. Butterworth Sci. Publications, London.Google Scholar
Klosterman, E. W., Cahill, V. R., Kunkle, L. E., & Moxon, A. L., 1955. The subcutaneous implantation of stilbestrol in fattening bulls and steers. J. Anim. Sci., 14: 1050 (Soc. Proa).Google Scholar
Lamming, G. E., 1957. The use of hormones in meat production. Agric. Progr., 32: 1.Google Scholar
Lamming, G. E., 1958. Recent developments in the use of growth stimulants. J. R. agric. Soc. Engl., 119: 41.Google Scholar
Martin, E. M., & Lamming, G. E., 1958. The effect of hexoestrol on the nucleic-acid content of the anterior pituitary gland of yearling male sheep. Proc. Nutrit. Soc. (Camb.), 17: 48.Google Scholar
O'Mary, C. C., Warren, E. P., Davis, T. J., & Pierce, H. H., 1956. Effects of low level implantations of stilbestrol in steers fattened on dry lot rations. J. Anim. Sci., 15: 52.CrossRefGoogle Scholar
Ontario Agricultural College, 1950. Ontario Advanced Registry for Beef Cattle. Ontario agric. Coll., Quelph, Ontario.Google Scholar
Pieterse, P. J. S., & Andrews, F. N., 1956. The estrogenic activity of alfalfa and other feedstuff's. J. Anim. Sci., 15: 25.CrossRefGoogle Scholar
Robinson, G. E., & Nalbandov, A. V., 1951. Changes in the hormone content of swine pituitaries during the estral cycle. J. Anim. Sci., 10: 469.CrossRefGoogle Scholar
Snedecor, G. W., 1946. Statistical Methods. Iowa State College Press, Ames, la.Google Scholar
Story, G. D., Cheng, E. W., Hale, W. H., & Burroughs, W., 1953. Growth and fattening responses in lambs fed natural estrogenic substances from soya-bean oil meal and certain pasture and hay crops. J. Anim. Sci., 12: 940.Google Scholar