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The effect of avoparcin on the ileal and faecal digestibility of nitrogen and amino acids in the milk-fed calf

Published online by Cambridge University Press:  02 September 2010

P. J. Moughan ,
E. V. J. Stevens ,
I. D. Reisima  and
J. Rendel
P. J. Moughan
Affiliation:
Department of Animal Science, Massey University, Palmerston North, New Zealand
E. V. J. Stevens
Affiliation:
Department of Animal Science, Massey University, Palmerston North, New Zealand
I. D. Reisima
Affiliation:
Department of Animal Science, Massey University, Palmerston North, New Zealand
J. Rendel
Affiliation:
Department of Animal Science, Massey University, Palmerston North, New Zealand
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Abstract

The study aimed to determine the effect of the growth promotant avoparcin on the digestion and absorption of nitrogen and amino acids from pre-ruminant milk-fed calves. Eighteen male Friesian calves, 45 kg live weight, were allocated to three diets: a commercial high-quality milk replacer compound (control); control with 100 mg zinc bacitracin per kg (positive control) and control with 40 mg avoparcin per kg. The diets were given once-daily at a set rate of intake during a 14-day metabolic study. On the 15th day the calves were fed at 2-h intervals and ileal digesta were sampled (8 h after the start of feeding) from the euthanazed animal. Estimates of apparent ileal digestibility were determined by reference to an indigestible marker, with the comparable faecal estimates determined following the total collection of faeces.

There was no significant effect of avoparcin or zinc bacitracin addition on faecal apparent digestibility of dry matter, nitrogen, gross energy and amino acids or on ileal apparent digestibility of nitrogen and amino acids. Neither was there a significant effect of either additive on nitrogen retention, daily urinary urea and total nitrogen excretions or portal and peripheral plasma urea concentrations. Ileal apparent digestibility coefficients determined on the control diet ranged from 0-82 for glycine to 0-96 for phenylalanine, tyrosine and methionine. The ileal measures of apparent digestibility were more variable than the comparable values determined over the entire digestive tract. Measurements on the faeces compared with measurements on digesta at the terminal ileum gave higher values (P < 0·05) of apparent digestibility for nitrogen and 10 of the 16 amino acids.

Type
Research Article
Information
Animal Production , Volume 49 , Issue 1 , August 1989 , pp. 63 - 71
Copyright
Copyright © British Society of Animal Science 1989

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References

REFERENCES

Association Of Official Analytical Chemists. 1975. Official Methods of Analysis of the Association of Official Analytical Chemists. 12th ed., p. 16. Association of Official Analytical Chemists, Washington, DC.Google Scholar
Badawy, A. M. 1964. Changes in the protein and non-protein nitrogen in the digesta of the sheep. In The Role of the Gastrointestinal Tract in Protein Metabolism (ed. Munro, H. N.), pp. 175–185. Blackwell, Oxford.Google Scholar
Blaxter, K. L. and Wood, W. A. 1951. The nutrition of the young Ayrshire calf. 1. The endogenous nitrogen and basal energy metabolism of the calf. British Journal of Nutrition 5: 11–25.CrossRefGoogle Scholar
Das, T. K. and Waterlow, J. C. 1974. The rate of adaptation of urea cycle enzymes, aminotransferases and glutamic dehydrogenase to changes in dietary protein intake. British Journal of Nutrition 32: 353–373.CrossRefGoogle ScholarPubMed
Davey, A. W. F. 1974. Nutrition of the pre-ruminant calf. Proceedings of the New Zealand Society of Animal Production 34: 133–144.Google Scholar
Edwards, J. R. 1986. Growth-promotion by antibacterial agents. In Laboratory Animals (ed. Ruitenberg, E. J. and Peters, P. W. J.), pp. 291–302. Elsevier, Amsterdam.Google Scholar
Emmons, D. B. and Lister, E. E. 1976. Quality of protein in milk replacers for young calves. I. Factors affecting in vitro curd formation by rennet (chymosin, rennin) from reconstituted skim milk powder. Canadian Journal of Animal Science 56: 317–325.CrossRefGoogle Scholar
Fenton, T. W. and Fenton, M. 1979. An improved procedure for the determination of chromic oxide in feed and feces. Canadian Journal of Animal Science 59: 631–634.CrossRefGoogle Scholar
Ferris, J. A. and Thomas, J. W. 1974. Relationship of immunoglobulin to dairy calf mortality and influence of herd environment. Journal of Dairy Science 57: 641 (Abstr.).Google Scholar
Guilloteau, P., Patureau-Mlrand, P., Toullec, R. and Pruonaud, J. 1980. Digestion of milk protein and methanol-grown bacteria protein in the preruminant calf. 2. Amino acid composition of ileal digesta and faeces and blood levels of free amino acids. Reproduction Nutrition Developpement 20: 615–629.CrossRefGoogle Scholar
Guilloteau, P. and Toullec, R. 1980. Digestion of milk protein and methanol-grown bacteria protein in the preruminant calf. 1. Kinetics and balance in the terminal small intestine and faecal balance. Reproduction Nutrition Développement 20: 601–613.CrossRefGoogle Scholar
Guilloteau, P., Toullec, R., Grongnet, J. F., Patureau-Mirand, P., Prugnaud, J. and Sauvant, D. 1986. Digestion of milk, fish and soya-bean protein in the preruminant calf: flow of digesta, apparent digestibility at the end of the ileum and amino acid composition of ileal digesta. British Journal of Nutrition 55: 571–592.CrossRefGoogle ScholarPubMed
Hellemond, K. K. van and Weerden, E. J. van. 1973. Milk-protein substitutes in rations for veal calves. Proceedings of the Nutrition Society 32: 231–235.CrossRefGoogle ScholarPubMed
Holmes, C. W. and Davey, A. W. F. 1976. The energy metabolism of young Jersey and Friesian calves led fresh milk. Animal Production 23: 43–53.Google Scholar
Jacobson, N. L. 1969. Energy and protein requirements of the calf. Journal of Dairy Science 52: 1316–1321.CrossRefGoogle ScholarPubMed
Jolliffe, I. T. 1972. Discarding variables in a principal component analysis. I. Artificial data. Applied Statistics 21: 160–173.CrossRefGoogle Scholar
Jolliffe, I. T. 1973. Discarding variables in a principal component analysis. II. Real data. Applied Statistics 22: 21–31.CrossRefGoogle Scholar
Just, A. 1980. Ileal digestibility of protein: applied aspects. In Current Concepts of Digestion and Absorption in Pigs (ed. Low, A. G. and Partridge, I. G.), pp. 66–75. National Institute for Research in Dairying, Reading.Google Scholar
Livingstone, R. M., Fowler, V. R. and McWilliam, R. 1982. The effect of two antibacterial agents in a pig diet on the digestibility of protein and organic matter measured at the terminal ileum and over the whole gut. Animal Production 34: 403–404 (Abstr.).Google Scholar
Lodge, G. A. and Lister, E. E. 1973. Effects of increasing the energy value of a whole milk diet for calves. I. Nutrient digestibility and nitrogen retention. Canadian Journal of Animal Science 53: 307–316.CrossRefGoogle Scholar
MacGregok, R. C. 1983. Growth promoters and their importance in ruminant livestock production. In Recent Advances in Animal Nutrition (ed. Haresign, W.). pp. 163–177. Butterworths, London.Google Scholar
MacGregor, R. C. and Armstrong, D. G. 1984. The feed antibiotic Avoparcin and net uptake of amino acids from the small intestine of sheep. Canadian Journal of Animal Science 64: Suppl., pp. 134–135.CrossRefGoogle Scholar
Mancini, G., Carbonara, A. O. and Herman, J. H. 1965. Immuno chemical quantitation of antigen by single radial immuno-diffusion. Immuno Chemistry 2: 235–254.CrossRefGoogle Scholar
Mardia, K. V., Kent, J. T. and Bibby, J. M. 1979. Multivariate Analysis. Academic Press. London.Google Scholar
Marsh, W. H., Finglrhut, B. and Miller, H. 1965. Automated and manual direct methods for the determination of blood urea. Clinical Chemistry 11: 624–627.CrossRefGoogle ScholarPubMed
Morrison, D. F. 1986. Multivariate Statistical Methods. McGraw Hill, Singapore.Google Scholar
Moughan, P. J. and Smith, W. C. 1985. Determination and assessment of apparent ileal amino acid digestibility coefficients for the growing pig. New Zealand Journal of Agricultural Research 28: 365–370.CrossRefGoogle Scholar
Nishimatsu, I. and Kumeno, F. 1965. Nutrition of young dairy calves. I. Study on chromic oxide and polyethylene glycol as index substances of digestion trials with young dairy calves. Journal of Zootechnical Science 36: 544–549.Google Scholar
Parker, D. S., MacGregor, R. C., Finlayson, H. J., Stockill, P. and Balios, J. 1984. The effect of including Avoparcin in the diet on cell turnover and enzyme activity in the mucosa of the rat small intestine. Canadian Journal of Animal Science 64: Suppi, pp. 136–137.CrossRefGoogle Scholar
Radostits, O. M. and Bell, J. M. 1968. Nutrient digestibility by new-born calves fed milk replacer. Canadian Journal of Animal Science 48: 293–302.CrossRefGoogle Scholar
Rayner, I. H., Smith, P. C. and Reid, J. 1970. Energy supplements to skim-milk for young calves. Proceedings of Australian Society of Animal Production 8: 252–257.Google Scholar
Wrong, O. M., Edmonds, C. J. and Chadwick, V. S. 1981. The Large Intestine: Its Role in Mammalian Nutrition and Homeostasis. MTP Press, Lancaster.Google Scholar
Zebrowska, T. 1975. The apparent digestibility of nitrogen and individual amino acids in the large intestine of pigs. Roczniki Nauk Rolniczych, Seria B 97: 117–123.Google Scholar