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The effects of halothane susceptibility on some economically important traits in pigs 1. Litter productivity

Published online by Cambridge University Press:  02 September 2010

A. E. Carden
Affiliation:
AFRC Animal Breeding Research Organisation, West Mains Road, Edinburgh EH9 3JQ
W. G. Hill
Affiliation:
Institute of Animal Genetics, University of Edinburgh, West Mains Road, Edinburgh EH9 3JN
A. J. Webb
Affiliation:
AFRC Animal Breeding Research Organisation, West Mains Road, Edinburgh EH9 3JQ
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Abstract

The effects of susceptibility to halothane anaesthesia on litter productivity were investigated by comparing susceptible and normal females in two sets of data. The first comprised 206 litters from the first five generations of Pietrain/Hampshire synthetic lines selected for and against halothane susceptibility. Susceptible and normal females were mated to boars of their own type. The second data set consisted of 93 litters from the same susceptible and normal females mated to normal boars. Compared with normal contemporaries, litter sizes of susceptible females were reduced by 1·16 (s.e. 0·40) piglets at birth, and 1-76 (s.e. 0·41) at weaning (ca. 1 weeks). Maximum likelihood estimates of the proportions of piglet deaths from birth to weaning as a trait of susceptible v. normal dams were 0·32 v. 014 (P < 0·001). There were no significant differences in piglet weights or perinatal mortality, and no apparent influence of piglet genotype on any trait. The lower litter size of susceptible females at weaning appeared to result from reductions in both numbers born and survival to weaning. The study bears out previous reports of a reduction in litter productivity due to the halothane gene. However, the present differences could have arisen largely from random genetic differentiation between lines, or linkage disequilibrium in the synthetic foundation population.

Type
Research Article
Copyright
Copyright © British Society of Animal Science 1985

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References

REFERENCES

Andresen, E. and Jensen, P. 1977. Close linkage established between the HAL locus for halothane sensitivity and the PHI (phosphohexose isomerase) locus in pigs of the Danish Landrace breed. Nord. VetMed. 29: 502504.Google ScholarPubMed
Baker, R. J. and Nelder, J. A. 1978. The GLIM System, Release 3, Manual. Numerical Algorithms Group, Oxford.Google Scholar
Carden, A. E. 1982. The genetics of halothane susceptibility in pigs. Ph.D. Thesis, Univ. Edinburgh.CrossRefGoogle Scholar
Carden, A. E. and Webb, A. J. 1984. The effect of age on halothane susceptibility in pigs. Anim. Prod. 38: 469475.Google Scholar
Eikelenboom, G., Minkema, D., Van Eldik, P. and Sybesma, W. 1978. Production characteristics of Dutch Landrace and Dutch Yorkshire pigs as related to their susceptibility for the halothane-induced malignant hyperthermia syndrome. Livest. Prod. Sci. 5: 277284.Google Scholar
Falconer, D. S. 1981. Introduction to Quantitative Genetics. 2nd ed. Longman, London.Google Scholar
Finney, D. J. 1970. Statistical Method in Biological Assay. 2nd ed. Griffin, London.Google Scholar
Hanset, R., Leroy, P., Michaux, C. and Kintaba, K. N. 1983. The Hal locus in the Belgian Pietrain breed. Z. Tierzucht. ZuchtBiol. 100: 123133.Google Scholar
Harvey, W. R. 1977. User's guide Tor LSML76. Mixed model least-squares and maximum likelihood computer program. The Ohio State Univ., Columbus. (Mimeograph).Google Scholar
Hill, W. G. 1980. Design of quantitative genetic selection experiments. In Selection Experiments in Laboratory and Domestic Animals (ed. Robertson, A.), pp. 113. Commonwealth Agricultural Bureaux, Slough.Google Scholar
Hill, W. G. and Webb, A. J. 1982. Genetics of reproduction in the pig. In Control of Pig Reproduction (ed. Cole, D. J. A. and Foxcroft, G. R.), pp. 541564. Butterworth, London.Google Scholar
Imlah, P. and Thompson, S. R. M. 1979. The H blood group locus and meat colour, and using blood groups ot predict halothane reactors. In Muscle Function and Porcine Meat Quality. Ada Agric. scand. Suppl. No. 21, pp. 403410.Google Scholar
Jensen, E. L., Smith, C., Baker, L. N. and Cox, D. F. 1968. Quantitative studies on blood group and serum protein systems in pigs. II. Effects on production and reproduction. J. Anim. Sci. 27: 856862.Google Scholar
Rgensen, P. F. 1978. Halothane sensitivity, the H blood group system and phosphohexose isomerase (PHI) in pigs. A linkage of physiological importance. Ada vet. scand. 19: 458460.CrossRefGoogle Scholar
Rasmusen, B. A. and Hagen, Karen L. 1973. The H blood-group system and reproduction in pigs. J. Anim. Sci. 37: 568573.CrossRefGoogle Scholar
Schneider, A., Schworer, D. and Blum, J. 1980. [Effect of halothane genotype on production and reproduction traits in Swiss Landrace.] Proc. 31st A. Meet. Eur. Ass. Anim. Prod., Munich, Pap. GP 3.9.Google Scholar
Smith, C. 1981. Genetic aspects of PSS and meat quality in pigs: breeding strategies with the halothane gene. In Porcine Stress and Meat Quality (ed. Froystein, T., Slinde, E. and Standal, N.), pp. 251259. Agricultural Food Research Society, As, Norway.Google Scholar
Smith, C. and Bampton, P. R. 1977. Inheritance of reaction to halothane anaesthesia in pigs. Genet. Res 29: 287292.Google Scholar
Webb, A. J., Carden, A. E., Smith, C. and Imlah, P. 1982. Porcine stress syndrome in pig breeding. Proc. 2nd Wld Congr. Genet. Appl. Livest. Prod., Madrid, Vol. 5, pp. 588608. Editorial Garsi, Madrid.Google Scholar
Webb, A. J. and Jordan, C. H. C. 1978. Halothane sensitivity as a field test for stress-susceptibility in pig. Anim. Prod. 26: 157168.Google Scholar