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The effect of GnRH analogue (buserelin) treatment on day 12 post mating on ovarian structure and plasma progesterone and oestradiol concentration in ewes

Published online by Cambridge University Press:  02 September 2010

N. F. G. Beck ,
M. Jones ,
B. Davies ,
G. E. Mann  and
A. R. Peters
N. F. G. Beck
Affiliation:
Department of Agricultural Sciences, University of Wales, Aberystwyth SY23 3DD
M. Jones
Affiliation:
Department of Agricultural Sciences, University of Wales, Aberystwyth SY23 3DD
B. Davies
Affiliation:
Department of Agricultural Sciences, University of Wales, Aberystwyth SY23 3DD
G. E. Mann
Affiliation:
Department of Physiology and Environmental Science, University of Nottingham, Sutton Bonington LE12 5RD
A. R. Peters
Affiliation:
Department of Animal Health, Royal Veterinary College, Potters Bar EN6 1NB
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Abstract

An investigation was conducted into the effect of buserelin treatment on day 12 post mating on ovarian function and plasma progesterone and oestradiol-17 ji concentration in ewes. Changes in ovarian structures were determined, at laparoscopy or after slaughter, 48 h after treatment in 38 control and 41 ewes given an injection of 4 jig buserelin on day 12 post mating (day 0 = day of oestrus). Ovulation rate was higher in buserelin treated (2·76) than in control (1·87) ewes (P < 0·05). Moreover, 41 of the 113 corpora lutea observed in the buserelin group were the result of ovulations that had occurred within 48 h post treatment, compared with two of 71 in the controls (P < 0·05). Blood samples were collected from 10 ewes in each treatment group for hormone analysis. Mean progesterone concentrations tended to be higher, in samples collected from 2 to 6h post treatment, in the buserelin group (4·31 (s.e. 1·32) p.g/1) compared with the control group (3·71 (s.e. 1·44) fig/l. Furthermore, overall mean oestradiol concentrations were lower, during days 13, 14 and 15 post mating, in buserelin treated (0·72 (s.e. 0·26) ngfl) than in control (0·94 (s.e. 0·50) ng/l) ewes (P < 0·05). The results of this study indicate that buserelin treatment on day 12 post mating changes ovarian function.

Keywords

buserelinewesoestradiolovariesprogesterone
Type
Research Article
Information
Animal Science , Volume 63 , Issue 3 , December 1996 , pp. 407 - 412
Copyright
Copyright © British Society of Animal Science 1996

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