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Non-antimicrobial approaches at drying-off for treating and preventing intramammary infections in dairy cows. Part 1. Meta-analyses of efficacy of using an internal teat sealant without a concomitant antimicrobial treatment

Published online by Cambridge University Press:  26 November 2019

Simon Dufour ,
Vincent Wellemans ,
Jean-Philippe Roy ,
Pierre Lacasse ,
Alfredo Ordonez-Iturriaga  and
David Francoz
Simon Dufour*
Affiliation:
Département de Pathologie et Microbiologie, Faculté de Médecine Vétérinaire, Université de Montréal, St-Hyacinthe, QC, J2S 2M2, Canada Canadian Bovine Mastitis and Milk Quality Research Network, St-Hyacinthe, QC, J2S 2M2, Canada
Vincent Wellemans
Affiliation:
Département de Sciences Cliniques, Faculté de Médecine Vétérinaire, Université de Montréal, St-Hyacinthe, QC, J2S 2M2, Canada
Jean-Philippe Roy
Affiliation:
Canadian Bovine Mastitis and Milk Quality Research Network, St-Hyacinthe, QC, J2S 2M2, Canada Département de Sciences Cliniques, Faculté de Médecine Vétérinaire, Université de Montréal, St-Hyacinthe, QC, J2S 2M2, Canada
Pierre Lacasse
Affiliation:
Canadian Bovine Mastitis and Milk Quality Research Network, St-Hyacinthe, QC, J2S 2M2, Canada Sherbrooke Research and Development Centre, Agriculture and Agri-Food Canada, 2000 Collège, Sherbrooke, QC, J1M 0C8, Canada
Alfredo Ordonez-Iturriaga
Affiliation:
Département de Sciences Cliniques, Faculté de Médecine Vétérinaire, Université de Montréal, St-Hyacinthe, QC, J2S 2M2, Canada
David Francoz
Affiliation:
Département de Sciences Cliniques, Faculté de Médecine Vétérinaire, Université de Montréal, St-Hyacinthe, QC, J2S 2M2, Canada
*
Author for correspondence: Simon Dufour, Département de Pathologie et Microbiologie, Faculté de Médecine Vétérinaire, Université de Montréal, St-Hyacinthe, QC, J2S 2M2, Canada. E-mail: [email protected]
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Abstract

Use of antimicrobial approaches at drying-off for preventing new intramammary infections (IMI) during the dry period in dairy cows could be replaced by non-antimicrobial approaches. Such approaches would be of interest not only for organic but also for conventional dairy producers. The objective of the current review was to quantify the effect of non-antimicrobial internal teat sealant (ITS)-based approaches at drying-off for treating and preventing IMI, when compared with no treatment or with an antimicrobial-based approach. The protocol for this review was published before initiating the review. A total of 18 trials from 16 articles could be used to investigate the effect of an ITS-based approach. With the available results, we conclude with a high level of confidence that non-antimicrobial ITS-based dry-off approaches are efficient for preventing new IMI during the dry period when compared with no treatment, and would reduce risk of new IMI by 52%. Moreover, we are relatively confident that a bismuth subnitrate-based ITS performed better than an antimicrobial for preventing new IMI during the dry period (a risk reduction of 23%). Similarly, we are relatively confident that an ITS-based approach would only slightly or not at all reduce the prevalence of IMI at calving compared with untreated quarters.

Keywords

Dairy cowsdry-off treatmentefficacyinternal teat sealantmeta-analysis
Type
Systematic Review
Information
Animal Health Research Reviews , Volume 20 , Issue 1 , June 2019 , pp. 86 - 97
Copyright
Copyright © Cambridge University Press 2019

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References

Aghamohammadi, M, Haine, D, Kelton, DF, Barkema, HW, Hogeveen, H, Keefe, GP and Dufour, S (2018) Herd-level mastitis-associated costs on Canadian dairy farms. Frontiers in Veterinary Science 5, 100.CrossRefGoogle ScholarPubMed
Berry, EA and Hillerton, JE (2002) The effect of an intramammary teat seal on new intramammary infections. Journal of Dairy Science 85, 2512–2520.CrossRefGoogle ScholarPubMed
Bhutto, AL, Murray, RD and Woldehiwet, Z (2011) The effect of dry cow therapy and internal teat-sealant on intra-mammary infections during subsequent lactation. Research in Veterinary Science 90, 316–320.CrossRefGoogle ScholarPubMed
Bradley, AJ and Green, MJ (2000) A study of the incidence and significance of intramammary enterobacterial infections acquired during the dry period. Journal of Dairy Science 83, 1957–1965.CrossRefGoogle ScholarPubMed
Bradley, AJ and Green, MJ (2004) The importance of the nonlactating period in the epidemiology of intramammary infection and strategies for prevention. Veterinary Clinic of North America Food Animal Practice 20, 547–568.CrossRefGoogle ScholarPubMed
Cameron, M, Mckenna, SL, Macdonald, KA, Dohoo, IR, Roy, JP and Keefe, GP (2014) Evaluation of selective dry cow treatment following on-farm culture: risk of postcalving intramammary infection and clinical mastitis in the subsequent lactation. Journal of Dairy Science 97, 270–284.CrossRefGoogle ScholarPubMed
Cengiz, M and Bastan, A (2015) Effectiveness of dry cow therapy comprising antibiotic treatment, internal teat sealant, and alpha-tocopherol against new intramammary infections in cows. Bulletin of the Veterinary Institute in Pulawy 59, 71–78.CrossRefGoogle Scholar
Compton, CWR, Emslie, FR and Mcdougall, S (2014) Randomised controlled trials demonstrate efficacy of a novel internal teat sealant to prevent new intramammary infections in dairy cows and heifers. New Zealand Veterinary Journal 62, 258–266.CrossRefGoogle ScholarPubMed
Dufour, S and Dohoo, IR (2013) Short communication: relationship between herd intramammary infection incidence and elimination rate during the dry period. Journal of Dairy Science 96, 1672–1676.CrossRefGoogle ScholarPubMed
Dufour, S, Frechette, A, Barkema, HW, Mussell, A and Scholl, DT (2011) Invited review: effect of udder health management practices on herd somatic cell count. Journal of Dairy Science 94, 563–579.CrossRefGoogle ScholarPubMed
Elecko, J, Federic, F and Vrtiak, OJ (1985) Dry period teat seal in the prevention of intramammary infections. Proceedings of 5th International symposium on mastitis control. pp. 225–234.Google Scholar
Francoz, D, Wellemans, V, Roy, JP, Lacasse, P, Ordonez-Iturriaga, A, Labelle, F and Dufour, S (2016) Non-antibiotic approaches at drying-off for treating and preventing intramammary infections: a protocol for a systematic review and meta-analysis. Animal Health Research Reviews 17, 169–175.CrossRefGoogle ScholarPubMed
Francoz, D, Wellemans, V, Dupre, JP, Roy, JP, Labelle, F, Lacasse, P and Dufour, S (2016) Invited review: a systematic review and qualitative analysis of treatments other than conventional antimicrobials for clinical mastitis in dairy cows. Journal of Dairy Science 100, 7751–7770.CrossRefGoogle Scholar
Guyatt, GH, Oxman, AD, Akl, EA, Kunz, R, Vist, G, Brozek, J, Norris, S, Falck-Ytter, Y, Glasziou, P, Debeer, H, Jaeschke, R, Rind, D, Meerpohl, J, Dahm, P and J, SH (2011 a) GRADE guidelines: 1. Introduction-GRADE evidence profiles and summary of findings tables. Journal of Clinical Epidemiology 64, 383–394.CrossRefGoogle ScholarPubMed
Guyatt, GH, Oxman, AD, Kunz, R, Brozek, J, Alonso-Coello, P, Rind, D, Devereaux, PJ, Montori, VM, Freyschuss, B, Vist, G, Jaeschke, R, Williams, JW Jr, Murad, MH, Sinclair, D, Falck-Ytter, Y, Meerpohl, J, Whittington, C, Thorlund, K, Andrews, J and Schunemann, HJ (2011 b) GRADE guidelines: 6. Rating the quality of evidence – imprecision. Journal of Clinical Epidemiology 64, 1283–1293.CrossRefGoogle ScholarPubMed
Guyatt, GH, Oxman, AD, Kunz, R, Woodcock, J, Brozek, J, Helfand, M, Alonso-Coello, P, Falck-Ytter, Y, Jaeschke, R, Vist, G, Akl, EA, Post, PN, Norris, S, Meerpohl, J, Shukla, VK, Nasser, M, Schunemann, HJ and Group, GW (2011 c) GRADE guidelines: 8. Rating the quality of evidence – indirectness. Journal of Clinical Epidemiology 64, 1303–1310.CrossRefGoogle ScholarPubMed
Guyatt, GH, Oxman, AD, Kunz, R, Woodcock, J, Brozek, J, Helfand, M, Alonso-Coello, P, Glasziou, P, Jaeschke, R, Akl, EA, Norris, S, Vist, G, Dahm, P, Shukla, VK, Higgins, J, Falck-Ytter, Y, Schunemann, HJ and Group, GW (2011 d) GRADE guidelines: 7. Rating the quality of evidence – inconsistency. Journal of Clinical Epidemiology 64, 1294–1302.CrossRefGoogle ScholarPubMed
Guyatt, GH, Oxman, AD, Montori, V, Vist, G, Kunz, R, Brozek, J, Alonso-Coello, P, Djulbegovic, B, Atkins, D, Falck-Ytter, Y, Williams, JW Jr, Meerpohl, J, Norris, SL, Akl, EA and Schunemann, HJ (2011 e) GRADE guidelines: 5. Rating the quality of evidence – publication bias. Journal of Clinical Epidemiology 64, 1277–1282.CrossRefGoogle ScholarPubMed
Guyatt, GH, Oxman, AD, Vist, G, Kunz, R, Brozek, J, Alonso-Coello, P, Montori, V, Akl, EA, Djulbegovic, B, Falck-Ytter, Y, Norris, SL, Williams, JW Jr, Atkins, D, Meerpohl, J and Schunemann, HJ (2011 f) GRADE guidelines: 4. Rating the quality of evidence – study limitations (risk of bias). Journal of Clinical Epidemiology 64, 407–415.CrossRefGoogle Scholar
Halasa, T, Osteras, O, Hogeveen, H, Van Werven, T and Nielen, M (2009) Meta-analysis of dry cow management for dairy cattle. Part 1. Protection against new intramammary infections. Journal of Dairy Science 92, 3134–3149.CrossRefGoogle ScholarPubMed
Huxley, JN, Green, MJ, Green, LE and Bradley, AJ (2002) Evaluation of the efficacy of an internal teat sealer during the dry period. Journal of Dairy Science 85, 551–561.CrossRefGoogle ScholarPubMed
Kabera, F, Dufour, S, Keefe, G and Roy, JP (2018) An observational cohort study on persistency of internal teat sealant residues in milk after calving in dairy cows. Journal of Dairy Science 101, 6399–6412.CrossRefGoogle ScholarPubMed
Klocke, P, Ivemeyer, S, Butler, G, Maeschli, A and Heil, F (2010) A randomized controlled trial to compare the use of homeopathy and internal teat sealers for the prevention of mastitis in organically farmed dairy cows during the dry period and 100 days post-calving. Homeopathy: the Journal of the Faculty of Homeopathy 99, 90–98.CrossRefGoogle ScholarPubMed
Kromker, V, Grabowski, NT and Friedrich, J (2014) New infection rate of bovine mammary glands after application of an internal teat seal at dry-off. Journal of Dairy Research 81, 54–58.CrossRefGoogle ScholarPubMed
Laven, RA and Lawrence, KE (2008) Efficacy of blanket treatment of cows and heifers with an internal teat sealant in reducing the risk of mastitis in dairy cattle calving on pasture. New Zealand Veterinary Journal 56, 171–175.CrossRefGoogle Scholar
Meaney, WJ (1977) Effect of a dry period teat seal on bovine udder infection. Irish Journal of Agricultural Research 16, 293.Google Scholar
Meaney, WJ (1986) Effect of dry period teat seal on bovine udder infection. In O'Shea, J (ed.), Moorepark 25th Anniversary Publication. II. Animal Health and Machine Milking. Dublin: An Foras Taluntais, pp. 249–265.Google Scholar
Mullen, KAE, Anderson, KL and Washburn, SP (2014) Effect of 2 herbal intramammary products on milk quantity and quality compared with conventional and no dry cow therapy. Journal of Dairy Science 97, 3509–3522.CrossRefGoogle ScholarPubMed
Petrovski, KR, Caicedo-Caldas, A, Williamson, NB, Lopez-Villalobos, N, Grinberg, A, Parkinson, TJ and Tucker, IG (2011) Efficacy of a novel internal dry period teat sealant containing 0.5% chlorhexidine against experimental challenge with Streptococcus uberis in dairy cattle. Journal of Dairy Science 94, 3366–3375.CrossRefGoogle ScholarPubMed
Rabiee, AR and Lean, IJ (2013) The effect of internal teat sealant products (Teatseal and Orbeseal) on intramammary infection, clinical mastitis, and somatic cell counts in lactating dairy cows: a meta-analysis. Journal of Dairy Science 96, 6915–6931.CrossRefGoogle ScholarPubMed
Saini, V, Mcclure, JT, Leger, D, Dufour, S, Sheldon, AG, Scholl, DT and Barkema, HW (2012) Antimicrobial use on Canadian dairy farms. Journal of Dairy Science 95, 1209–1221.CrossRefGoogle ScholarPubMed
Sanford, CJ, Keefe, GP, Dohoo, IR, Leslie, KE, Dingwell, RT, Descoteaux, L and Barkema, HW (2006) Efficacy of using an internal teat sealer to prevent new intramammary infections in nonlactating dairy cattle. Journal of the American Veterinary Medical Association 228, 1565–1573.CrossRefGoogle ScholarPubMed
Schaeren, W and Maurer, J (2005) The use of an internal teat sealant, Orbeseal, as a preventive measure fir the dry cow period. Proceedings of the 4th SAFO Workshop. p. 171.Google Scholar
Scherpenzeel, CGM, Den Uijl, IEM, Van Schaik, G, Riekerink, R, Hogeveen, H and Lam, T (2016) Effect of different scenarios for selective dry-cow therapy on udder health, antimicrobial usage, and economics. Journal of Dairy Science 99, 3753–3764.CrossRefGoogle ScholarPubMed
Woolford, MW, Williamson, JH, Day, AM and Copeman, PJA (1998) The prophylactic effect of a teat sealer on bovine mastitis during the dry period and the following lactation. New Zealand Veterinary Journal 46, 12–19.CrossRefGoogle ScholarPubMed
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