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Mycoplasma bovis pneumonia in cattle

Published online by Cambridge University Press:  24 January 2008

Jeff L. Caswell  and
Marie Archambault
Jeff L. Caswell*
Affiliation:
Department of Pathobiology, Ontario Veterinary College, University of Guelph, Guelph, ON, N1G 2W1, Canada
Marie Archambault
Affiliation:
Département de pathologie et microbiologie, Faculté de médecine vétérinaire, Université de Montréal, CP 5000, 3200 rue Sicotte, Saint-Hyacinthe, QC, J2S 7C6, Canada
*
*Corresponding author. E-mail: [email protected]
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Abstract

Mycoplasma bovis is an important and emerging cause of respiratory disease and arthritis in feedlot cattle and young dairy and veal calves, and has a variety of other disease manifestations in cattle. M. bovis is certainly capable of causing acute respiratory disease in cattle, yet the attributable fraction has been difficult to estimate. In contrast, M. bovis is more accepted as a cause of chronic bronchopneumonia with caseous and perhaps coagulative necrosis, characterized by persistent infection that seems poorly responsive to many antibiotics. An understanding of the disease has been recently advanced by comparisons of natural and experimentally induced disease, development of molecular diagnostic tools, and understanding some aspects of virulence, yet uncertainties regarding protective immunity, the importance of genotypic diversity, mechanisms of virulence, and the role of co-pathogens have restricted our understanding of pathogenesis and our ability to effectively control the disease. This review critically considers the relationship between M. bovis infection and the various manifestations of the bovine respiratory disease complex, and addresses the pathogenesis, clinical and pathologic sequelae, laboratory diagnosis and control of disease resulting from M. bovis infection in the bovine respiratory tract.

Keywords

Mycoplasma bovispneumoniaarthritisbacteriacattlereview
Type
Review Article
Information
Animal Health Research Reviews , Volume 8 , Issue 2 , December 2007 , pp. 161 - 186
Copyright
Copyright © Cambridge University Press 2008

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