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Commercialization of plant-based vaccines from research and development to manufacturing

Published online by Cambridge University Press:  28 February 2007

John A. Howard
John A. Howard*
Affiliation:
Biotechnology Institute, 5819 Stallion Ridge, College Station, TX 77845, USA
*
E-mail: [email protected]
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Abstract

The benefits of using plant-based oral vaccines are discussed. Transgenic maize expressing an antigen of transmissible gastroenteritis virus (TGEV) is reported as a model to demonstrate efficacy. Young pigs that were fed the TGEV corn orally were protected against challenge with virulent TGEV. Additional parameters important in providing a reliable and consistent supply of plant-based vaccines are discussed. Finally, vaccines developed in maize are evaluated for their potential to contaminate either the food supply or the environment.

Keywords

plant-based vaccinescommercialization
Type
Research Article
Information
Animal Health Research Reviews , Volume 5 , Issue 2 , December 2004 , pp. 243 - 245
Copyright
Copyright © CAB International 2004

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