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The Value of Measurement of Pregnancy-Specific Proteins in Twin Pregnancies

Published online by Cambridge University Press:  01 August 2014

V. Jandial ,
C. H. W. Horne ,
R. G. Glover ,
A. D. Nisbet ,
D. M. Campbell  and
I. MacGillivray
V. Jandial
Affiliation:
Department of Obstetrics and Gynaecology and Department of Pathology, University of Aberdeen, UK
C. H. W. Horne
Affiliation:
Department of Obstetrics and Gynaecology and Department of Pathology, University of Aberdeen, UK
R. G. Glover
Affiliation:
Department of Obstetrics and Gynaecology and Department of Pathology, University of Aberdeen, UK
A. D. Nisbet
Affiliation:
Department of Obstetrics and Gynaecology and Department of Pathology, University of Aberdeen, UK
D. M. Campbell
Affiliation:
Department of Obstetrics and Gynaecology and Department of Pathology, University of Aberdeen, UK
I. MacGillivray
Affiliation:
Department of Obstetrics and Gynaecology and Department of Pathology, University of Aberdeen, UK

Abstract

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In this study of 53 twin pregnancies, the plasma concentrations of the placental proteins, placental lactogen (hPL), and pregnancy-specific glycoprotein (SP1) were measured. Placental lactogen was found to be of more value than SP1 both in the detection of twins and in assessment of fetal growth. Serial measurement of either protein would seem to be more useful in assessment of fetal growth than single measurements. Preliminary studies of the less well known placental protein, PP5, in a small series of twin pregnancies indicate that it may also prove to be of clinical value in the detection and monitoring of twin pregnancies.

Keywords

Placental lactogenPregnancy-specific glycoproteinPlacental protein fivePlasma concentrationsTwin pregnancy
Type
Session III: Management of Twin Pregnancy
Information
Acta geneticae medicae et gemellologiae: twin research , Volume 28 , Issue 4 , October 1979 , pp. 319 - 325
Copyright
Copyright © The International Society for Twin Studies 1979

References

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