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Unusual Vascular Malformation of the Kidney in Both Twins of a Monozygotic Pair: Short Case Report

Published online by Cambridge University Press:  01 August 2014

G. Mastroberardino ,
A. Sciarra ,
R. Gualtieri ,
C. Di Fusco ,
P. Grammatico  and
G. Del Porto
G. Mastroberardino
Affiliation:
Fourth Chair of Clinical Medicine, First University of Rome, Italy
A. Sciarra
Affiliation:
Fourth Chair of Clinical Medicine, First University of Rome, Italy
R. Gualtieri
Affiliation:
Fourth Chair of Clinical Medicine, First University of Rome, Italy
C. Di Fusco
Affiliation:
Chair of Medical Genetics, School of Medicine, First University of Rome, Italy
P. Grammatico
Affiliation:
Chair of Medical Genetics, School of Medicine, First University of Rome, Italy
G. Del Porto*
Affiliation:
Chair of Medical Genetics, School of Medicine, First University of Rome, Italy
*
Via San Calepodio 7, 00152 Rome, Italy

Abstract

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A case of double bilateral renal vessels in both twins of a MZ pair is reported for the first time. Even in non-twins, the anomalies reported so far involved the inferior polar arteries in agreement with the embryological development. The two male twins, examined at the age of 14 years, had simultaneously developed a marked hypertension at the age of 7 years. Zygosity was determined by blood group and HLA analysis and various clinical tests were carried out to diagnose the condition. It is suggested that the anomaly is the result of a genetically induced early block in embryonic development.

Keywords

Vascular malformationTwinsKidney
Type
Research Article
Information
Acta geneticae medicae et gemellologiae: twin research , Volume 36 , Issue 4 , October 1987 , pp. 567 - 570
Copyright
Copyright © The International Society for Twin Studies 1987

References

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