Hostname: page-component-cd9895bd7-mkpzs Total loading time: 0 Render date: 2024-12-21T21:18:36.256Z Has data issue: false hasContentIssue false
  • English
  • Français

Twins with Acardia and Anencephaly

Published online by Cambridge University Press:  01 August 2014

L. Pavone ,
K.M. Laurence ,
T. Mattina ,
G. Nuciforo  and
F. Mollica
L. Pavone*
Affiliation:
Pediatric Clinic, University of Catania, Italy
K.M. Laurence
Affiliation:
The Welsh National School of Medicine, Cardiff, Wales
T. Mattina
Affiliation:
Pediatric Clinic, University of Catania, Italy
G. Nuciforo
Affiliation:
Institute of Pathologic Anatomy, University of Catania, Italy
F. Mollica
Affiliation:
Pediatric Clinic, University of Catania, Italy
*
Clinica Pediatrica I, Università di Catania, VI. A. Doria. 6, Catania, Italy

Abstract

Core share and HTML view are not available for this content. However, as you have access to this content, a full PDF is available via the ‘Save PDF’ action button.

The authors describe a pair of twins, one of whom showed acardia while the other had severe neural tube defect including anencephaly. This is the first observation of a fetal malformation (anencephaly) in the cotwin of an acardius and confirms the fact that even the cotwin of an acardiac fetus may be at risk of severe congenital malformations.

Keywords

AcardiaCraniorachischisisDiscordant monozygotic twins
Type
Case Report
Information
Acta geneticae medicae et gemellologiae: twin research , Volume 34 , Issue 1-2 , April 1985 , pp. 89 - 93
Copyright
Copyright © The International Society for Twin Studies 1985

References

REFERENCES

1. Alderman, B (1973): Foetus acardius amorphus. Postgrad Med J 49:102–105.Google Scholar
2. Benirschke, K (1981): Lessons from multiple pregnancies in mammals. In Gedda, L, Parisi, P, Nance, WE (eds): Twin Research 3: Part A, Twin Biology and Multiple Pregnancy. New York: Alan R. Liss, p 135–139.Google Scholar
3. Bieber, FR, Nance, WE, Morton, CC, Brown, JA, Redwine, FO (1981): Genetic studies of an acardiac monster: evidence of polar body twinning in man. Science 213:775–777.Google Scholar
4. Boronov, RC, West, RH (1964): Monster acardius parasiticus. Am J Obst Gynecol 88:233–237.Google Scholar
5. Grassi, G, Mitolo, GR (1955): La mostruosità acefalo-acardica (contributo casistico e considerazioni etio patogene tiene). Pathologica 47:335–359.Google Scholar
6. Kaplan, C, Benirschke, K (1979): The acardiac anomaly: New case reports and current status. Acta Genet Med Gemellol 28:51–59.Google Scholar
7. Moerman, P, Fryns, JP, Goddeeris, P, Lauweryns, JM, Van Assche, A (1983): Aberrant twinning (diprosopus) associated with anencephaly. Clin Genet 24:252–256.CrossRefGoogle ScholarPubMed
8. Nance, WA (1981: Malformations unique to the twinning process. In Gedda, L, Parisi, P, Nace, WE (eds): Twin Research 3: Part A, Twin Biology and Multiple Pregnancy. New York: Alan R. Liss, p 123–138.Google Scholar
9. Napolitani, FD, Schreiber, I (1960): The acardiac monster: A review of the world literature and presentation of 2 cases. Am J Obstet Gynecol 80:582–589.Google Scholar
10. Osathanondh, R, Driscoll, SG, Naftolin, F (1975): Discordant severe cranial defects in monozygotic twins. Am I Obstet Gynecol 122:301–305.Google Scholar
11. Rashad, MN, Kerr, MG (1966): Observations on the so-called holoacardius amorphus. J Anat 100: 425.Google Scholar
12. Richart, R, Benirschke, K (1963): Holoacardius Amorphus. Report of a case with chromosome analysis. Am J Obstet Gynecol 86:329–332.Google Scholar
13. Scott, JM, Ferguson-Smith, MA (1973): Heterokaryotypic monozygotic twins and the acardiac moster. J Obstet Gynecol Br Commonw 80:52–59.Google Scholar
14. Severn, CB, Holyoke, EA (1973): Human acardiac anomalies. Am J Obstet Gynecol 116:358–365.Google Scholar
15. Turpin, R, Bocquet, L, Grasset, J (1967): Etude d'une couple monozygote: fille normale-monster acardiacque féminin. Considérations anatomo-pathologiques et cytogénétiques. Ann Génét 10:107–113.Google Scholar
16. Warkany, J (1981): Congenital malformations. In: Year Book of Medical Pathology. Chicago, p. 473–474.Google Scholar