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The Stathmokinetic Agents

Published online by Cambridge University Press:  01 August 2014

L. Gedda  and
G. Cardinali
L. Gedda
Affiliation:
Istituto di Genetica Medica dell'Università di Roma
G. Cardinali
Affiliation:
Istituto di Genetica Medica dell'Università di Roma

Summary

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Stathmokinetic agents are a class of antimitotic agents which possess the ability of arresting cell division at the metaphase stage.

They are also called spindle poisons because they act by inactivating or distructing the mitotic spindle. Some new discovered stathmokinetic compounds, like vinblastine and vincristine, are effective anti-tumour agents. The mechanism of action of spindle poisons is briefly discussed.

Type
Research Article
Information
Acta geneticae medicae et gemellologiae: twin research , Volume 17 , Issue 1 , January 1968 , pp. 185 - 192
Copyright
Copyright © The International Society for Twin Studies 1968

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