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Report on a Pair of Male Monozygotic Twins Concordant for Schizophrenia

Published online by Cambridge University Press:  01 August 2014

Henry T. Lynch*
Affiliation:
Departments of Preventive Medicine and Public Health, Creighton University School of Medicine, Omaha, Nebraska
Louis Cohen
Affiliation:
Departments of Psychiatry and Neurology, Creighton University School of Medicine, Omaha, Nebraska
Arnold R. Kaplan
Affiliation:
Laboratory of Medical Genetics, Cleveland Psychiatric Institute, Cleveland, Ohio, USA
Jane Lynch
Affiliation:
Laboratory of Medical Genetics, Cleveland Psychiatric Institute, Cleveland, Ohio, USA
*
Department of Preventive Medicine and Public Health, Creighton University School of Medicine, 2500 California Street, Omaha, Nebraska 68131, USA

Summary

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A pair of MZ twins with diagnoses of chronic simple schizophrenia has been studied from the genetic, social, medical, and psychiatric standpoint by members of the several professions. Clinical psychologists studied the patients independently and on the basis of psychometric and projective tests found a remarkable similarity in personality profiles. An in-depth family study failed to reveal any evidence of psychiatric disease in other relatives. Consanguinity was absent. The family unit is typical of that described frequently for a schizophrenogenic household, i.e., dominant mother, passive father. Genetic etiologies are discussed in context with occurrence of schizophrenia in MZ twins in this particular family setting.

Type
Research Article
Copyright
Copyright © The International Society for Twin Studies 1972

References

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