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Presence of an Endothelioid Tubelike Structure at the Interface of the Amniotic Membranes in Twins with Single and Double Placenta. Growth Factors Involvement

Published online by Cambridge University Press:  01 August 2014

M. Bondì ,
G. Brenci  and
M. Bondì Jr.
M. Bondì*
Affiliation:
The Gregor Mendel Institute of Medical Genetics and Twin Studies, Rome, Italy
G. Brenci
Affiliation:
The Gregor Mendel Institute of Medical Genetics and Twin Studies, Rome, Italy
M. Bondì Jr.*
Affiliation:
The Gregor Mendel Institute of Medical Genetics and Twin Studies, Rome, Italy
*
Mendel Institute, Piazza Galeno 5, 00162 Rome, Italy
Mendel Institute, Piazza Galeno 5, 00162 Rome, Italy

Abstract

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A histomorphological study of the amniotic membranes in full-term twins with double and single placenta was carried out by means of the silver impregnation staining technique suitably modified. Specimens of interface of amniotic membranes were prepared by means of sections. The constant presence of a tubelike structure was observed. Proceeding from the amniotic cavity, the following histological layers were noted: 1) single layer of amniotic cells; 2) amorphic substance with fibrocytes; 3) single layer of endothelial cells. The same order of single layer is present in the amniotic membrane of the second fetus. This tubelike structure is present only in cases of twins with double placenta. If the placenta is single with two umbilical cords, the tubelike structure is not present and only a central amorphic substance surrounded by two single layers of amniotic cells is observed, to confirm the single embryogenetic derivation (monovular). Therefore, through this histological method, we can recognize the true single placenta of twin pregnancy from the pseudosingle placenta so said for the presence of adherences of adjoining surfaces that make it appear single. On the contrary, by manual dissection it is possible to identify a twin pregnancy with two placentae. From the physiological point of view, the walls of the tubelike structure have probably the function to realize exchanges of amniotic liquids between the two fetuses, so as to obtain a balance of electrolytic ions and of intercavity pressure. Growth factors (vascular endothelial factor) are probably involved in the genesis of the endothelial tubelike structure.

Keywords

Twin placentationEndothelioid tubelike structureGrowth factors
Type
Research Article
Information
Acta geneticae medicae et gemellologiae: twin research , Volume 40 , Issue 1 , January 1991 , pp. 91 - 99
Copyright
Copyright © The International Society for Twin Studies 1991

References

REFERENCES

1.Alderman, EM, Lobb, RR, Fett, JW, Riordan, JF, Bethune, JL, Vallee, BL (1985): Angiogenic activity of human tumor plasma membrane components. Biochemistry 24:7866–7871.CrossRefGoogle ScholarPubMed
2.Bondì, M (1946): Ulteriori contributi alla tecnica della impregnazione argentica per i contorni cellulari. Boll Soc It Sperim 32.Google Scholar
3.Bondì, M (1956): Sulla specificità dei tessuti costituenti le sierose in stato di flogosi. (Studio istomorfologico). Rend Ist Sup Sanità 19:1217–1229.Google Scholar
4.Bondì, M (1957): Sugli endoteli e le cellule di rivestimento delle sierose (Studio istol. e fisiopat.). Rend Ist Sup Sanità 20:39–50.Google Scholar
5.Cameron, AH (1968): The Birmingham twin survey. Proc Roy Soc Med 61:229.CrossRefGoogle ScholarPubMed
6.Cohen, S, Levi-Montalcini, R, Hamburger, V (1954): A nerve growth stimulating factor isolated from sarcoma 37&180. Proc Natur Acad Sci USA 40:1014.Google Scholar
7.Cohen, S, Levi-Montalcini, (1956): Proc Natur Acad Sci USA 42:571.CrossRefGoogle Scholar
8.Folkman, J (1974): Tumor Angiogenesis. Adv Cancer Res 19:331–358.CrossRefGoogle ScholarPubMed
9.Folkman, J, Cotran, R (1976): Relation of vascular proliferation to tumor growth. Int Rev Exp Pathol 16:207–247.Google Scholar
10.Levi-Montalcini, R (1987): The nerve growth factor 35 years later. Science 237:1154–1160.Google Scholar
11.Levi-Montalcini, R (1989): Neuroscience in the XXI Century Proc Congr Washington.Google Scholar
12.Levi-Montalcini, R (1989): NGF: Apertura di una Nuova Frontiera nella Neurobiologia. Roma-Napoli: Ediz. Theoria.Google Scholar
13.Mingeot, R (1980): La grossesse et l'accouchement gémellaires. IX Jour Nat Soc Fran de Medic Perinatale, Paris; Librairie Arnette.Google Scholar
14.Nylander, PPS (1969): The value of the placenta in the determination of zigosity. A study of 1052 Nigerian twin maternities. J Obst Gyn Brit Comm 76:699.CrossRefGoogle Scholar
15.Pledger, WJ, Stiles, CD, Antoniades, HN, Schery, CD (1977): Induction of DNA synthesis in Balb/c cells by serum components: Revaluation of the committent process. Proc Nat Acad Sci USA 74:4481–4485.Google Scholar
16.Shapiro, R, Strydom, DJ, Olson, KA, Vallee, BL (1987): Isolation of angiogenin from normal human plasma. Biochemistry 26:5141–5146.CrossRefGoogle ScholarPubMed
17.Steward, FC (1985): Plant Physiology: A Treatise. New York: Acad. Press.Google Scholar
18.Vrijens, M, Derom, R, Thiery, M (1976): Morfologische studie van de placenta van twe clingen. V Congr Nat SRBGO 60Google Scholar