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On Some Theoretical Studies on Gene Differentiation in Natural Populations*

Published online by Cambridge University Press:  01 August 2014

Ranajit Chakraborty
Ranajit Chakraborty*
Affiliation:
Center for Demographic and Population Genetics, University of Texas Health Science Center, Houston, Texas, USA
*
Center for Demographic and Population Genetics, University of Texas Health Science Center, Houston, Texas 77025, USA

Abstract

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Different mathematical approaches to study the extent of genetic variation of natural populations are reviewed. The modern understanding of the gene structure permits new interpretations of existing concepts like fixation or inbreeding. A more recent measure of genie divergence, which at molecular level is designed to measure net codon differences is also seen to be related with gene diversity in a substructed population. It is argued that such variations are produced and preserved possibly by simultaneous action of migration, mutation, selection, and random genetic drift. At the present moment it is very difficult to isolate out the effect of each factor because of varying degrees of variation at the different gene sites and between different sets of populations.

Type
Research Article
Information
Acta geneticae medicae et gemellologiae: twin research , Volume 24 , Issue 1-2 , January 1975 , pp. 111 - 117
Copyright
Copyright © The International Society for Twin Studies 1975

Footnotes

*

Based on the author's presentation in a panel discussion on “Genetic and evolutionary factors in human differentiation” during the Ninth International Congress of Anthropological and Ethnological Sciences held at Chicago, September 1973. Research supported by Grant GM 19513-02 from the U.S. National Institutes of Health.

References

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