Published online by Cambridge University Press: 01 August 2014
Two familial cases (father and son) of Addison disease, occurred after « asian influenza », are reported.
Clinical data suggest tat the pathological basis for adrenal insufficiency could be the so-called « simple fibrosclerosis » and that virus infection has acted as a precipitating factor of an underlying adrenal meyopragy, since both patients as well as other members of the same familyi have a hyperpigmentated skin.
The two patients have shown a Addison syndrome « partially compensate » with incomplete symptomatology for lack of functional adrenal reserve which has been detected only by ACTH stimulation (which was inefficient).
As far as we know, this is the first report of a chronic hypercorticalism occurred in the father and one of his sons.
Il lavoro spetta in parti uguali ai due autori. II Direttore.