Hostname: page-component-78c5997874-v9fdk Total loading time: 0 Render date: 2024-11-08T07:29:01.650Z Has data issue: false hasContentIssue false

Maternal Factors Associated with Small-for-Dateness Among Twins

Published online by Cambridge University Press:  01 August 2014

Denis Hemon*
Affiliation:
Unité de Recherches Epidémiologiques et Statistiques sur l'Environnement et la Santé, INSERM U 170, Villejuif, France
Colette Berger
Affiliation:
Unité de Recherches Epidémiologiques et Statistiques sur l'Environnement et la Santé, INSERM U 170, Villejuif, France
Philippe Lazar
Affiliation:
Unité de Recherches Epidémiologiques et Statistiques sur l'Environnement et la Santé, INSERM U 170, Villejuif, France
*
INSERM, U 170 Statistiques, 16 Avenue P. V. Couturier, 94807 Villejuif Cedex, France

Abstract

Core share and HTML view are not available for this content. However, as you have access to this content, a full PDF is available via the ‘Save PDF’ action button.

The maternal risk factors that correlate with small-for-dateness among twins have been analyzed using a sample of 659 twin pairs and a matched sample of singletons. Non-marital status, job involvement, and the previous delivery of a low-birth weight (<2,500g) infant present a negative interaction with twinning, as low gestational age-adjusted birth weight does not correlate significantly with these risk factors among twin gestations, while it does among singleton gestations. On the other hand, the effects of parity, habitual maternal weight, smoking during pregnancy, and twinning are additive on gestational age-adjusted birth weight. Indeed, the decrease in adjusted birth weight associated with these risk factors is of the same magnitude among twins and singletons and is statistically significant in both cases. These findings suggest that exposure of twin pregnancies to these latter risk factors, and particularly to smoking during pregnancy, can lead to the delivery of newborns with extremely low birth weights.

Type
Research Article
Copyright
Copyright © The International Society for Twin Studies 1982

References

REFERENCES

1. Asaka, A, Imaizumi, Y, Inouye, E (1980): Analysis of multiple births in Japan. Jpn J Hum Genet 25:213218.Google Scholar
2. Bleker, OP, Kloosterman, GJ, Huidekoper, BL, Breur, W (1977): Intrauterine growth of twins as estimated from birthweight and the fetal biparietal diameter. Eur J Obstet Gynecol 7:8590.Google Scholar
3. Bleker, OP, Breur, W, Huidekoper, BL (1979): A study of birthweight, placental weight and mortality of twins as compared to singletons. Br J Obstet Gynecol 86:111118.Google Scholar
4. Bulmer, MG (1970): “The Biology of Twinning in Man.” Oxford: Clarendon Press.Google Scholar
5. Chanrasia, AR (1980): Perinatal mortality in twins. Acta Genet Med 29:237239.Google Scholar
6. Corey, LA, Nance, WE, Kang, KW, Christian, JC (1979): Effects of type of placentation on birthweight and its variability in monozygotic and dizygotic twins. Acta Genet Med 28:4150.Google Scholar
7. Corney, G, Robson, EB, Strong, SJ (1972): The effect of zygosity on the birthweight of twins. Ann Hum Genet 36:4559.Google Scholar
8. Corney, G, Thompson, B, Campbell, DM, Macgillivray, I, Seedburgh, D, Timlin, D (1979): The effect of zygosity on the birthweight of twins in Aberdeen and Northeast Scotland. Acta Genet Med 28:353360.Google Scholar
9. Fabia, J, Drolette, M (1980): Twin pairs, smoking in pregnancy and perinatal mortality. Am J Epidemiol 112:404408.Google Scholar
10. Gedda, L, Brenchi, G, Gatti, J (1981): Low birthweight in twins versus singletons: Separate entities and different implications for child growth and survival. Acta Genet Med 30:18.Google Scholar
11. Hemon, D, Berger, C, Lazar, P (1979): The epidemiology of human dizygotic twinning with special reference to spontaneous abortions. Acta Genet Med 28:253258.Google Scholar
12. Grennert, L, Persson, PH, Gennser, G, Gullberg, B (1980): Zygosity and intrauterine growth of twins. Obstet Gynecol 55:684687.Google Scholar
13. Houlton, MCC, Marivate, M, Philpott, RH (1981): The prediction of fetal growth retardation in twin pregnancy. Br J Obstet Gynecol 88:264273.Google Scholar
14. Keith, L, Ellis, R, Berger, G, Depp, R, Eilstead, W, Hatcher, R, Keith, DM (1980): The Northwestern University multihospital twin study: 1. A description of 588 twin pregnancies and associated pregnancy loss, 1971 to 1975. Am J Obstet Gynecol 138:781789.Google Scholar
15. MacCarthy, BJ, Sachs, BP, Layde, PM, Burton, A, Terry, JS, Rochat, R (1981): The epidemiology of neonatal deaths in twins. Am J Obstet Gynecol 141:252256.Google Scholar
16. MacGillivray, I, Nylander, PPS, Corney, G (1975): “Human Multiple Reproduction.” London, Philadelphia, Toronto: WB Saunders.Google Scholar
17. Manlan, G, Scott, KE (1978): Contribution of twin pregnancy to perinatal mortality and fetal growth retardation; reversal of growth retardation after birth. Can Med Assoc J 118:365368.Google ScholarPubMed
18. Petersson, F, Smedby, B, Lindmark, G (1976): Outcome of twin births. Review of 1636 children born in twin births. Acta Paedtr Scand 65:473–179.Google Scholar