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Maternal Alcohol and Pentazocine Abuse: Neonatal Behavior and Morphology in an Opposite-Sex Twin Pair

Published online by Cambridge University Press:  01 August 2014

Marilyn L. Riese
Marilyn L. Riese*
Affiliation:
Louisville Twin Study, University of Louisville School of Medicine, Kentucky, USA
*
Louisville Twin Study, Department of Pediatrics, University of Louisville, Louisville, KY 40292, USA

Abstract

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A pair of preterm, opposite-sex twins were examined during the lying-in period for behavioral and morphological effects of maternal alcohol and pentazocine abuse during pregnancy. A few morphological features typical of fetal alcohol syndrome were observed in each infant, and the male infant only was above the standardized mean in minor physical anomalies. The male's behavioral scores were more likely to be deviant from the standardized mean than the female's. Specifically, the male was more irritable, both spontaneously and in response to specific stimuli; highly active while awake and handled for the presentation of stimuli; more active than average during sleep; and low on ratings that reflect the attitude of the examiner toward the infant. These findings imply individual and gender differences in behavioral susceptibility to teratogens.

Keywords

TwinsAlcohol abuseDrug abuseNeonatal behaviorSex differences
Type
Research Article
Information
Acta geneticae medicae et gemellologiae: twin research , Volume 38 , Issue 1-2 , April 1989 , pp. 49 - 56
Copyright
Copyright © The International Society for Twin Studies 1989

References

REFERENCES

1. Chasnoff, IJ (1985): Fetal alcohol syndrome in twin pregnancy. Acta Genet Med Gemellol 34:229–232.Google Scholar
2. Christoffel, KK, Salafsky, I (1975): Fetal alcohol syndrome in dizygotic twins. J Pediatrics 87:963–967.CrossRefGoogle ScholarPubMed
3. Dunn, DW, Reynolds, J (1982): Neonatal withdrawal symptoms associated with “T's and Blues” (Pentazocine and Tripelennamine). Child 136:644–645.Google Scholar
4. Finnegan, LP (1982): Outcome of children born to women dependent upon narcotics. In Stimmel, B. (ed.): The Effects of Maternal Alcohol and Drug Abuse on the Newborn, Vol. 1. New York: The Haworth Press, pp. 653–723.Google Scholar
5. Finnegan, LP, O'Brien Fehr, K. (1980): The effects of opiates, sedative-hypnotics, amphetamines, cannabis, and other psychoactive drugs on the fetus and newborn. In Kalant, OJ (ed.): Alcohol and Drug Problems in Women, Vol. 5. New York: Plenum Press, pp.653–723.CrossRefGoogle Scholar
6. Goetz, RL, Bain, RV (1974): Neonatal withdrawal symptoms associated with maternal use of pentazocine. J Pediatrics, 84:887–888.Google Scholar
7. Jones, KL, Smith, DW, Ulleland, CN, Streissguth, AP (1973): Pattern of malformation in offspring of chronic alcoholic mothers. Lancet, 1:1267–1271.Google Scholar
8. Kopelman, AE (1975): Fetal addiction to pentazocine. Pediatrics, 55:888–889.CrossRefGoogle ScholarPubMed
9. Preis, O, Choi, SJ, Rudolph, N (1977): Pentazocine withdrawal syndrome in the newborn infant. Am Obstet Gynecol, 127: 205–206.CrossRefGoogle ScholarPubMed
10. Riese, ML (1982): Procedures and norms for assessing behavioral patterns in full-term and stable pre-term neonates. JSAS Catalog of Selected Documents in Psychology, 12: 6 (MS. No. 2415).Google Scholar
11. Riese, ML (1983): Assessment of behavioral patterns in neonates. Infant Behav Dev, 6: 241–246.Google Scholar
12. Riese, ML (1983): Behavioral patterns in full-term and pre-term twins. Acta Genet Med Gemellol, 32: 209–220.Google Scholar
13. Rosett, HL (1980): The effects of alcohol on the fetus and offspring. In Kalant, OJ (ed.): Alcohol and Drug Problems in Women, Vol. 5. New York: Plenum Press, pp. 595–652.Google Scholar
14. Rosett, HL, Snyder, P, Sander, LW, Lee, A, Cook, P, Weiner, L, Gould, J. (1979): Effects of maternal drinking on neonate state regulation. Dev Med Chil Neurol 21: 464–473.Google Scholar
15. Scanlon, JW (1974): Pentazocine and neonatal withdrawal symptoms. J Pediatrics 85: 735.Google Scholar
16. Schwartz, RH, Yaffe, SJ (eds.) (1980): Drug and Chemical Risks to the Fetus and Newborn. New York: Alan R. Liss, Inc.Google Scholar
17. Singer, JE, Westphal, M, Niswander, KR (1968): Sex differences in the incidence of neonatal abnormalities and abnormal performance in early childhood. Child Dev 39: 103–112.CrossRefGoogle ScholarPubMed
18. Smith, D (1970): Recognizable Patterns of Human Malformation. Philadelphia: Saunders.Google ScholarPubMed
19. Smith, DW (1980): Alcohol effects on the fetus. In Schwartz, RH, Yaffe, SJ (eds.): Drugs and Chemical Risks to the Fetus and Newborn. New York: Alan R. Liss, pp. 73–82.Google Scholar
20. Stimmel, B (ed.) (1982): The Effects of Maternal Alcohol and Drug Abuse on the Newborn, Vol. 1. New York: The Haworth Press.Google Scholar
21. Streissguth, AP (1976): Maternal acoholism and the outcome of pregnancy: A review of the fetal alcohol syndrome. In Greenblatt, M., Schuckit, A. (eds.): Alcoholism Problems in Women and Children. New York: Grune and Stratton, pp. 251–274.Google Scholar
22. Streissguth, AP, Landesman-Dwyer, S, Martin, JC, Smith, DW (1980): Teratogenic effects of alcohol in humans and laboratory animals. Science, 209: 353–361.Google Scholar
23. Waldrop, MF, Halverson, CF Jr, (1971): Minor physical anomalies and hyperactive behavior in young children. In Hellmuth, J. (ed.): The Exceptional Infant, Vol. 2: Studies in Abnormalities. New York: Brunner/Mazel, pp. 343–389.Google Scholar