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Published online by Cambridge University Press: 01 August 2014
41 children with acute leukemia were treated with Vincristine Sulphate. Total remission was obtained in 17 out of 22 patients (77%) in whom Vincristine was used as the first drug.
19 patients who had been treated previously with other antimitotic drugs and have become resistant to them, received Vincristine: total remission occurred in 7 cases and partial remission in 3 cases within 4-10 weeks of therapy.
A case is reported of a child still surviving three years and seven months from the beginning of the disease and two years and 4 months from completion of therapy with Vincristine.