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Is Weinberg's Differential Rule Valid?

Published online by Cambridge University Press:  01 August 2014

William H. James
William H. James*
Affiliation:
The Galton Laboratory, University College, London

Abstract

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Weinberg's differential method, whereby the frequency of dizygotic twins in a population is obtained by doubling the number of opposite-sexed pairs, might not be valid. Data are presented indicating a higher frequency of same-sexed than opposite-sexed pairs among samples of dizygotic twins ascertained at birth, thus favoring the hypothesis that, contrary to the method's fundamental assumption, the sexes of the two twin zygotes be not independent.

Keywords

Weinberg's methodSex determinationDizygotic twinningAutosomal markersAscertainment at birth
Type
Brief-Report
Information
Acta geneticae medicae et gemellologiae: twin research , Volume 28 , Issue 1 , January 1979 , pp. 69 - 71
Copyright
Copyright © The International Society for Twin Studies 1979

References

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