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Influences Comparees de l'Age Maternel et de l'Age Paternel sur l'Apparition de la Trisomie G Libre

Published online by Cambridge University Press:  01 August 2014

Y. Ros*
Affiliation:
Laboratoire de Génétique Médicale, Faculté de Médecine et de Pharmacie, Université Libre de Bruxelles, Belgique
*
Laboratoire de Génétique Médicale, Rue aux Laines, 97, 1000 Bruxelles, Belgium

Summary

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In order to study the influence of maternal and of paternal age on the incidence of standard trisomy G, two samples were compared, one of 335 trisomic and one of 330 normal children in the same age range.

The results show an increasing incidence of the anomaly with maternal age, whereas nothing could be concluded concerning paternal age.

Type
Research Article
Copyright
Copyright © The International Society for Twin Studies 1973

References

BIBLIOGRAPHIE

Dagfinn, Aarskog 1969. Down's syndrome transmitted through maternal mosaicism. Acta Paediat. Scand., 58: 609614.Google Scholar
Benda, C.E., Strassmann, G.S. 1965. The thymus in mongolism. J. Ment. Defic. Res., 9: 109117.Google Scholar
Carter, C.O., Evans, K.A., Stewart, A.M. 1961. Maternal radiation and Down's syndrome (mongolism). Lancet, 2: 678680.Google Scholar
Collmann, R.D., Stoller, A. 1962. A survey of mongoloid birth in Victoria, Australia 1942-1957. Am. J. Publ. Health, 52: 813820.Google Scholar
Chitam, R.G., Mac Iver, E. 1965. A cytogenetic and statistical survey of 105 cases of mongolism. Ann. Hum. Genet., 28: 309315.Google Scholar
Evans, H.J. 1967. The nucleolus, virus infection, and trisomy in man. Nature (Lond.), 214: 361363.Google Scholar
Fialkow, P.J. 1966. Autoimmunity and chromosome aberrations. Am. J. Hum. Genet., 18: 93108.Google Scholar
Fialkow, P.J., Uchida, J.A. 1968. Autoantibodies in Down's syndrome and gonadal dysgenesis. Ann. N.Y. Acad. Sci., 155: 759762.Google Scholar
Fialkow, P.J., Thuline, H.C., Hecht, F., Bryant, J. 1971. Familial predisposition to thyroid disease in Down's syndrome. Controlled immunological studies. Am. J. Hum. Genet., 23: 6786.Google Scholar
Gustavson, K.H. 1964. Down's Syndrome. A Clinical and Cytogenetical Investigation. Almqvist. and Wiksells, Uppsala, pp. 196.Google Scholar
Hall, B., Kallen, B. 1964. Chromosome studies in abortuses and stillborn infants. Lancet, 1: 110111.Google Scholar
Hanah, A. 1955. Environment factors affecting elimination of the ring X-chromosome in Drosophila melanogaster. Z. Vererbungslehre Bd., 86: 600621.Google Scholar
Hamerton, J.L., Cowie, V.A., Giannelli, F., Briggs, S.M., Polani, P. 1961. Differential transmission of Down's syndrome (mongolism) through male and female translocation carriers. Lancet, 2: 956958.Google ScholarPubMed
Hamerton, J.L., Giannelli, F., Polani, P. 1965. Cytogenetics of Down's syndrome (mongolism). Cytogenetics, 4: 171185.Google Scholar
Hayashi, T. 1963. Karyotyping analysis of 83 cases of Down's syndrome in Harris Country, Texas. Texas Rep. Biol. Med., 21: 2836.Google Scholar
Huang, S.W., Emmanuel, I., Lo, T., Liao, S.K., Hsu, C. 1967. A cytogenetic study of 77 Chinese children with Down's syndrome. J. Ment. Defic. Res., 11: 147152.Google Scholar
Matsunaga, E. 1967. Mongolism. Ciba Foundation study group no. 25. S. & A. Churchill, London.Google Scholar
Nichols, W., Levan, A., Hall, B., Ostergren, G. 1962. Measles associated chromosome breakage. A preliminary communication. Hereditas, 48: 367370.Google Scholar
Penrose, L.S. 1933. Relative effects of paternal and maternal age in mongolism. J. Genet., 27: 219227.Google Scholar
Penrose, L.S., Ellis, J.R., Delhanty, J.D.A. 1960. Chromosomal translocations in mongolism and in normal relatives. Lancet, 2: 409410.Google Scholar
Penrose, L.S., Smith, F.G. 1966. Down's Anomaly. J. & A. Churchill, London.Google Scholar
Polani, P.E. 1963. Cytogenetics of Down's syndrome. Pediat. Clin. North Am., 10: 423447.Google Scholar
Richards, B.W., Stewart, A., Sylvester, P.E., Jasiewiczv, . 1965. Cytogenetic survey of 225 patients diagnosed clinically as mongols. J. Ment. Defic. Res., 9: 245259.Google Scholar
Sigler, A.T., Lilienfield, A.M. 1965. Parental age in Down's syndrome (mongolism). J. Pediatr., 67: 631642.Google ScholarPubMed
Schuler, D., Koos, R., Siegler, J., Horvath, L. 1970. Thyroid auto antibodies and satellites association in Down's syndrome. Hum. Hered., 20: 1318.Google Scholar
Twiesselmann, F. 1971. Développement Biométrique de l'Enfant à l'Adulte. Presses Universitaires de Bruxelles, Librairie Malone, Paris.Google Scholar
Vanhaelst, L., Hayez, F., Bonnyns, M., Bastenie, P. A. 1970. Thyroid autoimmune disease and thyroid function in families of subjects with Down's syndrome. J. Clin. Endocrinol. Metab., 30: 792797.Google Scholar