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Genetics of the Rh-Hr Locus in Humans

Published online by Cambridge University Press:  01 August 2014

Syed Shane Raza Zaidi ,
Sue Bebon  and
Syed Hasan Hadi Taqvi
Syed Shane Raza Zaidi*
Affiliation:
Department of Pathology, Philadelphia College of Osteopathic Medicine, Philadelphia, Pennsylvania, USA Pakistan Defence Science Organization, Chaklala-Rawalpindi, Pakistan
Sue Bebon
Affiliation:
Department of Pathology, Philadelphia College of Osteopathic Medicine, Philadelphia, Pennsylvania, USA Pakistan Defence Science Organization, Chaklala-Rawalpindi, Pakistan
Syed Hasan Hadi Taqvi
Affiliation:
Department of Pathology, Philadelphia College of Osteopathic Medicine, Philadelphia, Pennsylvania, USA Pakistan Defence Science Organization, Chaklala-Rawalpindi, Pakistan
*
Strahlenbiologisches Institut der Universität, Bavariaring 19, 8 Munich 2, German Federal Republic

Abstract

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An analysis is attempted to throw more light on the inheritance of rhesus factor in humans and the Fisher-Race and Wiener's concepts are respectively evaluated.

It is claimed that the Rh-Hr locus is not comprised of the recombination of C, D, E, c and e genes, much less the help of the auxiliary (d) which merely appears to be a conventional approach derived from an even principle of recombination for a polyhybrid cross.

As for Wiener's rare or common mutants of Rh-Hr in humans and the emergence of different agglutinogens like a sort of genetic proliferation, no such parallel of inheritance has yet been found in experimental plants or animals.

Probably the scarcity of certain genotypes is due to the rare chance of fertilization or embryonic development due to incompatibility between certain mutants of Rh-Hr genes, similar to ABO-Rh incompatibility.

Type
Research Article
Information
Acta geneticae medicae et gemellologiae: twin research , Volume 24 , Issue 1-2 , January 1975 , pp. 137 - 144
Copyright
Copyright © The International Society for Twin Studies 1975

References

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