Published online by Cambridge University Press: 01 August 2014
After a historical review of the problem of progressive myoclonic epilepsy, the author makes a detailed clinical and genetic description of 5 families from the Valais canton, affected with the disease. The metabolic disturbances observed in these cases (urinary elimination of mucopolysaccharides) are given particular attention. The author further discusses the various classifications of myoclonic epilepsy which were established on the basis of clinical symptomatology, electroencephalographic tracings, pathological anatomy and biochemical findings.
Travail subventionné par le Fonds National Suisse de la Recherche Scientifique (Crédit No. 4408) et par le Public Health Service, Bethesda, Md., USA (NB 04590-05).
Ce travail est dédié en hommage sincère au Prof. D. Klein pour son soixantième anniversaire.