Hostname: page-component-cd9895bd7-dk4vv Total loading time: 0 Render date: 2024-12-25T02:53:36.948Z Has data issue: false hasContentIssue false
  • English
  • Français

Determinants of Ridge Counts in MZ Twin Kinships

Published online by Cambridge University Press:  01 August 2014

M. C. Phelan ,
W. E. Nance  and
L. A. Corey
M. C. Phelan
Affiliation:
Department of Human Genetics, Medical College of Virginia, Richmond
W. E. Nance
Affiliation:
Department of Human Genetics, Medical College of Virginia, Richmond
L. A. Corey*
Affiliation:
Department of Human Genetics, Medical College of Virginia, Richmond
*
Department of Human Genetics, MCV Station, Box 33, Richmond, VA 23298, USA

Abstract

Core share and HTML view are not available for this content. However, as you have access to this content, a full PDF is available via the ‘Save PDF’ action button.

The inheritance of total ridge count (TRC) was studied in 967 individuals from the families of 111 pairs of MZ twins. The sample included data on 47 male half-sibships with 227 offspring and 64 female half-sibships with 306 offspring. The males in this sample had a mean ridge count of 135 ± 2 and the females a mean ridge count of 124 ± 2. The distribution of scores for females showed evidence for significant skewness. For this reason, prior to the analysis, the data were corrected for sex and adjusted to normality using a power transformation. Nested analyses of variance were performed on the ridge counts from male and female half-sibships separately to derive estimates of among, between, and within-variance components. These estimates were then used in a nonlinear least squares program to estimate genetic and environmental parameters and to determine the goodness of fit of various models. A model which included additive genetic and dominance effects could not be rejected (P = 0.67) but did not fit the data as well as a simple additive genetic-random environmental model (P = 0.81). The addition of maternal effects to the latter model also provided a satisfactory fit (P = 0.68). However, there was no improvement in the goodness of fit over the simple model, and the estimated magnitude of the maternal effect was not significantly different from zero.

Keywords

Total ridge countMZ twin kinshipsAdditive genetic effects
Type
Research Article
Information
Acta geneticae medicae et gemellologiae: twin research , Volume 30 , Issue 1 , January 1981 , pp. 59 - 66
Copyright
Copyright © The International Society for Twin Studies 1981

References

REFERENCES

1.Armitage, P (1971): “Statistical Methods in Medical Research.” New York: John Wiley and Sons.Google Scholar
2.Cummins, H, Midlo, C (1943): “Finger Prints, Palms and Soles.” New York: Dover.Google Scholar
3.Elston, RC (1975): On the correlation between correlations. Biometrika 62:133–140.Google Scholar
4.Holt, SB (1952): Genetics of dermal ridges: Inheritance of total finger ridge-count. Ann Eugen, Lond 17:140–161.Google ScholarPubMed
5.Holt, SB (1964): Fingerprint patterns in mongolism. Ann Hum Genet, Lond 27:279–282.Google Scholar
6.Holt, SB (1968): “The Genetics of Dermal Ridges.” Springfield, Illinois: Charles C Thomas.Google Scholar
7.Holt, SB, Lindsten, J (1964): Dermatoglyphic anomalies in Turner syndrome. Ann Hum Genet, Lond 28:87–100.CrossRefGoogle Scholar
8.Lints, F, Parisi, P (1980): Variations of heritability as a function of parental age. (Abstract). Acta Genet Med Gamellol 29:46.Google Scholar
9.Nance, WE, Corey, LA (1976): Genetic models for the analysis of data from the families of identical twins. Genetics 83:811–826.CrossRefGoogle ScholarPubMed
10.Nance, WE, Corey, LA, Boughman, JA (1978): Monozygotic twin kinships: A new design for genetic and epidemiological research. In Morton, NE, Chung, CS (eds): “Genetic Epidemiology.” New York: Academic Press, pp 87–132.Google Scholar
11.Ohler, EA, Cummins, H (1942): Sexual differences in breadths of epidermal ridges on the fingertips and palms. Amer J Phys Anthropol 29:341–362.Google Scholar
12.Penrose, LS (1967): Fingerprint pattern and the sex chromosomes. Lancet 1:298–300.Google Scholar
13.Preus, M, Fraser, FC (1972): Dermatoglyphics and syndromes. Am J Dis Child 124:933–943.Google Scholar
14.Spence, MA, Elston, RC, Namboodiri, KK, Pollitzer, WS (1973): Evidence for a possible major gene effect in absolute finger ridge count. Hum Hered 23:414–421.CrossRefGoogle ScholarPubMed
15.Spence, MA, Westlake, J, Lange, K (1977): Estimation of the variance components for dermal ridge count. Ann Hum Genet, Lond 41:111–115.Google Scholar
16.Uchida, IA, Miller, JR, Soltan, HC (1964): Dermatoglyphics associated with the XXYY chromosome complement. Am J Hum Genet 16:284–291.Google Scholar