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Cytogenetic Observations in Infertile Men Working with Insecticidal Compounds

Published online by Cambridge University Press:  27 January 2025

Fiorella Shabtai ,
Shlomo Bichacho  and
Isaac Halbrecht
Fiorella Shabtai
Affiliation:
B. Gattegno Research Institute of Human Reproduction and Fetal Development, Hasharon Hospital, Petah-Tiqva Tel Aviv University Sackler School of Medicine, Tel Aviv, Israel
Shlomo Bichacho
Affiliation:
B. Gattegno Research Institute of Human Reproduction and Fetal Development, Hasharon Hospital, Petah-Tiqva Tel Aviv University Sackler School of Medicine, Tel Aviv, Israel
Isaac Halbrecht*
Affiliation:
B. Gattegno Research Institute of Human Reproduction and Fetal Development, Hasharon Hospital, Petah-Tiqva Tel Aviv University Sackler School of Medicine, Tel Aviv, Israel
*
B. Gattegno Research Institute of Human Reproduction and Fetal Development, Hasharon Hospital, Petah-Tiqva, Israel

Abstract

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The negative influence of some insecticides on male fertility has been noted. We report our cytogenetic observations on a group of infertile insecticide workers. Increased chromosomal breakage was a constant finding and the Y chromosome was especially damaged. This may account for impaired spermatogenesis. Furthermore, the involvement of heterochromatic chromosomal variants both in the individual susceptibility to the chemically induced damage and in the reproductive fitness is emphasized.

Type
Research Article
Information
Acta geneticae medicae et gemellologiae: twin research , Volume 27 , January 1978 , pp. 51 - 56
Copyright
Copyright © The International Society for Twin Studies 1978

References

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