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Cholinesterase, Arylesterase, and Lipoprotein Parameters in Twins

Published online by Cambridge University Press:  01 August 2014

Helge Boman
Helge Boman*
Affiliation:
Institute of Medical Genetics, University of Oslo, Norway
*
Institute of Medical Genetics, University of Oslo, PO Box 1036, Blindern, Oslo 3, Norway

Abstract

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A high heritability estimate was obtained for serum arylesterase activity level in a series of 40 male twin pairs (23 MZ, 17 DZ) aged 33–39 years. The heritability estimated for Cholinesterase activity was strikingly lower. In unrelated individuals a positive correlation between arylesterase, Cholinesterase, and various lipoprotein parameters appeared to support the suggestion that these enzymes interact with various lipoproteins at the molecular level. The nature of these associations is not known. It is, however, tempting to speculate that some of the hereditary influence on lipoprotein levels in man may be mediated through the genetic control of one or both of these enzymes.

Keywords

Heritability estimatesCholinesteraseArylesteraseCholesterolTriglyceridesLipoproteinsTwins
Type
Research Article
Information
Acta geneticae medicae et gemellologiae: twin research , Volume 29 , Issue 4 , October 1980 , pp. 281 - 287
Copyright
Copyright © The International Society for Twin Studies 1980

References

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